Leyline of Hope

If Leyline of Hope is in your opening hand, you may begin the game with it on the battlefield.
If you would gain life, you gain that much life plus 1 instead.
As long as you have at least 7 life more than your starting life total, creatures you control get +2/+2.

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Archangel of Thune

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Whenever you gain life, put a +1/+1 counter on each creature you control.

City of Brass

Whenever City of Brass becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Soul Warden

Whenever another creature enters, you gain 1 life.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Orzhov Signet

Cradle of Vitality

Whenever you gain life, you may pay {1}{W}. If you do, put a +1/+1 counter on target creature for each 1 life you gained.

Absorb

Serra Avatar

Serra Avatar's power and toughness are each equal to your life total.
When Serra Avatar is put into a graveyard from anywhere, shuffle it into its owner's library.

Swamp

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature of their choice and you return up to one target creature card from your graveyard to your hand.

Arcane Signet

Celestine, the Living Saint

Flying, lifelink
Healing Tears — At the beginning of your end step, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Dovin's Veto

This spell can't be countered.
Counter target noncreature spell.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Essence Channeler

As long as you've lost life this turn, Essence Channeler has flying and vigilance.
Whenever you gain life, put a +1/+1 counter on Essence Channeler.
When Essence Channeler dies, put its counters on target creature you control.

No Mercy

Whenever a creature deals damage to you, destroy it.

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Sol Ring

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Land Tax

At the beginning of your upkeep, if an opponent controls more lands than you, you may search your library for up to three basic land cards, reveal them, put them into your hand, then shuffle.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Lunar Convocation

At the beginning of your end step, if you gained life this turn, each opponent loses 1 life.
At the beginning of your end step, if you gained and lost life this turn, create a 1/1 black Bat creature token with flying.
{1}{B}, Pay 2 life: Draw a card.

Island

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Meathook Massacre II

When Meathook Massacre II enters, each player sacrifices X creatures of their choice.
Whenever a creature you control dies, you may pay 3 life. If you do, return that card under your control with a finality counter on it.
Whenever a creature an opponent controls dies, they may pay 3 life. If they don't, return that card under your control with a finality counter on it.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Ocelot Pride

First strike, lifelink
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your end step, if you gained life this turn, create a 1/1 white Cat creature token. Then if you have the city's blessing, for each token you control that entered this turn, create a token that's a copy of it.

Angelic Accord

At the beginning of each end step, if you gained 4 or more life this turn, create a 4/4 white Angel creature token with flying.

Gloomlake Verge

{T}: Add {U}.
{T}: Add {B}. Activate only if you control an Island or a Swamp.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Felidar Sovereign

Vigilance (Attacking doesn't cause this creature to tap.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Caduceus, Staff of Hermes

Equipped creature has lifelink.
As long as you have 30 or more life, equipped creature gets +5/+5 and has indestructible and "Prevent all damage that would be dealt to this creature."
Equip {W}{W}

The Gaffer

At the beginning of each end step, if you gained 3 or more life this turn, draw a card.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Azorius Signet

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Queza, Augur of Agonies

Whenever you draw a card, target opponent loses 1 life and you gain 1 life.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Counterspell

Ajani's Pridemate

Whenever you gain life, put a +1/+1 counter on Ajani's Pridemate.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is Esper Sentinel's power.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Academy Ruins

{T}: Add {C}.
{1}{U}, {T}: Put target artifact card from your graveyard on top of your library.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Thought Vessel

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Floodfarm Verge

{T}: Add {W}.
{T}: Add {U}. Activate only if you control a Plains or an Island.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Fountain of Renewal

At the beginning of your upkeep, you gain 1 life.
{3}, Sacrifice Fountain of Renewal: Draw a card.

Plains

Hallowed Fountain

({T}: Add {W} or {U}.)
As Hallowed Fountain enters, you may pay 2 life. If you don't, it enters tapped.

The Book of Exalted Deeds

At the beginning of your end step, if you gained 3 or more life this turn, create a 3/3 white Angel creature token with flying.
{W}{W}{W}, {T}, Exile The Book of Exalted Deeds: Put an enlightened counter on target Angel. It gains "You can't lose the game and your opponents can't win the game." Activate only as a sorcery.

Sigarda's Splendor

As Sigarda's Splendor enters, note your life total.
At the beginning of your upkeep, draw a card if your life total is greater than or equal to the last noted life total for Sigarda's Splendor. Then note your life total.
Whenever you cast a white spell, you gain 1 life.

Elenda's Hierophant

Flying
Whenever you gain life, put a +1/+1 counter on Elenda's Hierophant.
When Elenda's Hierophant dies, create X 1/1 white Vampire creature tokens with lifelink, where X is its power.