Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Disciple of Bolas

When Disciple of Bolas enters, sacrifice another creature. You gain X life and draw X cards, where X is that creature's power.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Veinwitch Coven

Menace
Whenever you gain life, you may pay {B}. If you do, return target creature card from your graveyard to your hand.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Sign in Blood

Target player draws two cards and loses 2 life.

Sinister Monolith

At the beginning of combat on your turn, each opponent loses 1 life and you gain 1 life.
{T}, Pay 2 life, Sacrifice Sinister Monolith: Draw two cards. Activate only as a sorcery.

Species Specialist

As Species Specialist enters, choose a creature type.
Whenever a creature of the chosen type dies, you may draw a card.

Vindictive Vampire

Whenever another creature you control dies, Vindictive Vampire deals 1 damage to each opponent and you gain 1 life.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Corrupt

Corrupt deals damage to any target equal to the number of Swamps you control. You gain life equal to the damage dealt this way.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Shard of the Nightbringer

Flying
Drain Life — When Shard of the Nightbringer enters, if you cast it, target opponent loses half their life, rounded up. You gain life equal to the life lost this way.

Consume Spirit

Spend only black mana on X.
Consume Spirit deals X damage to any target and you gain X life.

Gollum, Obsessed Stalker

Skulk (This creature can't be blocked by creatures with greater power.)
At the beginning of your end step, each opponent dealt combat damage this game by a creature named Gollum, Obsessed Stalker loses life equal to the amount of life you gained this turn.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Basilisk Collar

Equipped creature has deathtouch and lifelink.
Equip {2}

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Scion of the Swarm

Flying
Whenever you gain life, put a +1/+1 counter on Scion of the Swarm.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Feast of Blood

Cast this spell only if you control two or more Vampires.
Destroy target creature. You gain 4 life.

Bloodbond Vampire

Whenever you gain life, put a +1/+1 counter on Bloodbond Vampire.

Ancient Craving

You draw three cards and you lose 3 life.

Sun Droplet

Whenever you're dealt damage, put that many charge counters on Sun Droplet.
At the beginning of each upkeep, you may remove a charge counter from Sun Droplet. If you do, you gain 1 life.

Baleful Ammit

Lifelink
When Baleful Ammit enters, put a -1/-1 counter on target creature you control.

Gifted Aetherborn

Damnation

Destroy all creatures. They can't be regenerated.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Prism Ring

As Prism Ring enters, choose a color.
Whenever you cast a spell of the chosen color, you gain 1 life.

Vraan, Executioner Thane

Whenever one or more other creatures you control die, each opponent loses 2 life and you gain 2 life. This ability triggers only once each turn.

Marauding Blight-Priest

Vampiric Rites

{1}{B}, Sacrifice a creature: You gain 1 life and draw a card.

Night's Whisper

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Silversmote Ghoul

At the beginning of your end step, if you gained 3 or more life this turn, return Silversmote Ghoul from your graveyard to the battlefield tapped.
{1}{B}, Sacrifice Silversmote Ghoul: Draw a card.

Ambition's Cost

Vampire Nighthawk

Vault Skirge

({B/P} can be paid with either {B} or 2 life.)
Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Wedding Invitation

When Wedding Invitation enters, draw a card.
{T}, Sacrifice Wedding Invitation: Target creature can't be blocked this turn. If it's a Vampire, it also gains lifelink until end of turn.

Swamp

Mutilate

All creatures get -1/-1 until end of turn for each Swamp you control.

Scrib Nibblers

{T}: Exile the top card of target player's library. If it's a land card, you gain 1 life.
Landfall — Whenever a land you control enters, you may untap Scrib Nibblers.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Infernal Grasp

Destroy target creature. You lose 2 life.

Jet Medallion

Black spells you cast cost {1} less to cast.

Wall of Limbs

Defender (This creature can't attack.)
Whenever you gain life, put a +1/+1 counter on Wall of Limbs.
{5}{B}{B}, Sacrifice Wall of Limbs: Target player loses X life, where X is Wall of Limbs's power.

Indulgent Aristocrat

Lifelink
{2}, Sacrifice a creature: Put a +1/+1 counter on each Vampire you control.

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Syphon Soul

Syphon Soul deals 2 damage to each other player. You gain life equal to the damage dealt this way.

Fell

Gixian Puppeteer

Whenever you draw your second card each turn, each opponent loses 2 life and you gain 2 life.
When Gixian Puppeteer dies, return another target creature card with mana value 3 or less from your graveyard to the battlefield.

Gibbering Barricade

Defender
{2}{B}, Sacrifice a creature: You gain 1 life and draw a card.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Blood Tithe

Each opponent loses 3 life. You gain life equal to the life lost this way.

Kindred Dominance

Choose a creature type. Destroy all creatures that aren't of the chosen type.

Diamond Mare

As Diamond Mare enters, choose a color.
Whenever you cast a spell of the chosen color, you gain 1 life.

Demon's Horn

Whenever a player casts a black spell, you may gain 1 life.

Sanctum Seeker

Whenever a Vampire you control attacks, each opponent loses 1 life and you gain 1 life.

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Breathe Your Last

Destroy target creature or planeswalker. You gain 1 life for each of its colors.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Vampire Cutthroat

Skulk (This creature can't be blocked by creatures with greater power.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Greed

Tavern Swindler

{T}, Pay 3 life: Flip a coin. If you win the flip, you gain 6 life.

Sorin's Vengeance

Sorin's Vengeance deals 10 damage to target player or planeswalker and you gain 10 life.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Withering Torment

Destroy target creature or enchantment. You lose 2 life.

Pristine Talisman

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Kokusho, the Evening Star

Flying
When Kokusho, the Evening Star dies, each opponent loses 5 life. You gain life equal to the life lost this way.