Congregate

Target player gains 2 life for each creature on the battlefield.

Rottenmouth Viper

As an additional cost to cast this spell, you may sacrifice any number of nonland permanents. This spell costs {1} less to cast for each permanent sacrificed this way.
Whenever Rottenmouth Viper enters or attacks, put a blight counter on it. Then for each blight counter on it, each opponent loses 4 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Caustic Bronco

Whenever Caustic Bronco attacks, reveal the top card of your library and put it into your hand. You lose life equal to that card's mana value if Caustic Bronco isn't saddled. Otherwise, each opponent loses that much life.
Saddle 3 (Tap any number of other creatures you control with total power 3 or more: This Mount becomes saddled until end of turn. Saddle only as a sorcery.)

Massacre Wurm

When this creature enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Wurm's Tooth

Whenever a player casts a green spell, you may gain 1 life.

Serra Paragon

Flying
Once during each of your turns, you may play a land from your graveyard or cast a permanent spell with mana value 3 or less from your graveyard. If you do, it gains "When this permanent is put into a graveyard from the battlefield, exile it and you gain 2 life."

Drag the Canal

Create a 2/2 white and blue Detective creature token. If a creature died this turn, you gain 2 life, surveil 2, then investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Regal Caracal

Other Cats you control get +1/+1 and have lifelink. (Damage dealt by those creatures also causes you to gain that much life.)
When this creature enters, create two 1/1 white Cat creature tokens with lifelink.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Forever Young

Put any number of target creature cards from your graveyard on top of your library.
Draw a card.

Ayara, Furnace Queen

At the beginning of combat on your turn, return up to one target artifact or creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step.

Ayara, Widow of the Realm

{T}, Sacrifice another creature or artifact: Ayara, Widow of the Realm deals X damage to target opponent or battle and you gain X life, where X is the sacrificed permanent's mana value.
{5}{R/P}: Transform Ayara. Activate only as a sorcery. ({R/P} can be paid with either {R} or 2 life.)

Ayara, Widow of the Realm // Ayara, Furnace Queen

Rattleback Apothecary

Deathtouch
Whenever you commit a crime, target creature you control gains your choice of menace or lifelink until end of turn. (Targeting opponents, anything they control, and/or cards in their graveyards is a crime.)

Absorb Vis

Target player loses 4 life and you gain 4 life.
Basic landcycling {1}{B} ({1}{B}, Discard this card: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.)

Glidedive Duo

Flying
When Glidedive Duo enters, each opponent loses 2 life and you gain 2 life.

Shattered Seraph

Flying
When Shattered Seraph enters, you gain 3 life.
{2}, Exile Shattered Seraph from your hand: Target land gains "{T}: Add {W}, {U}, or {B}" until Shattered Seraph is cast from exile. You may cast Shattered Seraph for as long as it remains exiled.

Servant of Tymaret

Inspired — Whenever Servant of Tymaret becomes untapped, each opponent loses 1 life. You gain life equal to the life lost this way.
{2}{B}: Regenerate Servant of Tymaret.

Vein Ripper

Flying
Ward—Sacrifice a creature.
Whenever a creature dies, target opponent loses 2 life and you gain 2 life.

Light of Promise

Enchant creature
Enchanted creature has "Whenever you gain life, put that many +1/+1 counters on this creature."

Essence Channeler

As long as you've lost life this turn, Essence Channeler has flying and vigilance.
Whenever you gain life, put a +1/+1 counter on Essence Channeler.
When Essence Channeler dies, put its counters on target creature you control.

Vampire Scrivener

Flying
Whenever you gain life during your turn, put a +1/+1 counter on Vampire Scrivener.
Whenever you lose life during your turn, put a +1/+1 counter on Vampire Scrivener.

Sorin's Thirst

Sorin's Thirst deals 2 damage to target creature and you gain 2 life.

Cleric Class

(Gain the next level as a sorcery to add its ability.)
If you would gain life, you gain that much life plus 1 instead.
{3}{W}: Level 2
Whenever you gain life, put a +1/+1 counter on target creature you control.
{4}{W}: Level 3
When this Class becomes level 3, return target creature card from your graveyard to the battlefield. You gain life equal to that creature's toughness.

Tribute to Hunger

Target opponent sacrifices a creature of their choice. You gain life equal to that creature's toughness.

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Arbiter of Woe

As an additional cost to cast this spell, sacrifice a creature.
Flying
When this creature enters, each opponent discards a card and loses 2 life. You draw a card and gain 2 life.

Bloodthirsty Conqueror

Flying, deathtouch
Whenever an opponent loses life, you gain that much life. (Damage causes loss of life.)

Famished Paladin

Famished Paladin doesn't untap during your untap step.
Whenever you gain life, untap Famished Paladin.

Marina Vendrell's Grimoire

When Marina Vendrell's Grimoire enters, if you cast it, draw five cards.
You have no maximum hand size and don't lose the game for having 0 or less life.
Whenever you gain life, draw that many cards.
Whenever you lose life, discard that many cards. Then if you have no cards in hand, you lose the game.

Swift Justice

Until end of turn, target creature gets +1/+0 and gains first strike and lifelink.

Nadier's Nightblade

Whenever a token you control leaves the battlefield, each opponent loses 1 life and you gain 1 life.

Unscrupulous Contractor

When Unscrupulous Contractor enters, you may sacrifice a creature. When you do, target player draws two cards and loses 2 life.
Plot {2}{B} (You may pay {2}{B} and exile this card from your hand. Cast it as a sorcery on a later turn without paying its mana cost. Plot only as a sorcery.)

It That Rides as One

Lone Rider

First strike, lifelink
At the beginning of the end step, if you gained 3 or more life this turn, transform Lone Rider.

Lone Rider // It That Rides as One

Kokusho, the Evening Star

Flying
When Kokusho, the Evening Star dies, each opponent loses 5 life. You gain life equal to the life lost this way.

Damnation

Destroy all creatures. They can't be regenerated.

Metamorphosis Fanatic

Lifelink
When Metamorphosis Fanatic enters, return up to one target creature card from your graveyard to the battlefield with a lifelink counter on it.
Miracle {1}{B} (You may cast this card for its miracle cost when you draw it if it's the first card you drew this turn.)

Chastise

Destroy target attacking creature. You gain life equal to its power.

Archon of Cruelty

Flying
Whenever Archon of Cruelty enters or attacks, target opponent sacrifices a creature or planeswalker of their choice, discards a card, and loses 3 life. You draw a card and gain 3 life.

Lethal Vapors

Whenever a creature enters, destroy it.
{0}: Destroy Lethal Vapors. You skip your next turn. Any player may activate this ability.

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice Gonti's Machinations: Each opponent loses 3 life. You gain life equal to the life lost this way.

Tymna the Weaver

Lifelink
At the beginning of each of your postcombat main phases, you may pay X life, where X is the number of opponents that were dealt combat damage this turn. If you do, draw X cards.
Partner (You can have two commanders if both have partner.)

MacCready, Lamplight Mayor

Whenever a creature you control with power 2 or less attacks, it gains skulk until end of turn. (It can't be blocked by creatures with greater power.)
Whenever a creature with power 4 or greater attacks you, its controller loses 2 life and you gain 2 life.

Kwain, Itinerant Meddler

{T}: Each player may draw a card, then each player who drew a card this way gains 1 life.

Inspiring Overseer

Flying
When this creature enters, you gain 1 life and draw a card.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Firja, Judge of Valor

Flying, lifelink
Whenever you cast your second spell each turn, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Vampire's Bite

Kicker {2}{B} (You may pay an additional {2}{B} as you cast this spell.)
Target creature gets +3/+0 until end of turn. If this spell was kicked, that creature gains lifelink until end of turn. (Damage dealt by the creature also causes its controller to gain that much life.)

Thrull Parasite

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
{T}, Pay 2 life: Remove a counter from target nonland permanent.

Soured Springs

Soured Springs enters tapped.
When Soured Springs enters, it deals 1 damage to target opponent.
{T}: Add {U} or {B}.

Traveling Minister

{T}: Target creature gets +1/+0 until end of turn. You gain 1 life. Activate only as a sorcery.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

The Gaffer

At the beginning of each end step, if you gained 3 or more life this turn, draw a card.

Athreos, God of Passage

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
Whenever another creature you own dies, return it to your hand unless target opponent pays 3 life.

Sengir, the Dark Baron

Flying
Whenever another creature dies, put two +1/+1 counters on Sengir, the Dark Baron.
Whenever another player loses the game, you gain life equal to that player's life total as the turn began.
Partner (You can have two commanders if both have partner.)

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Case of the Uneaten Feast

Whenever a creature you control enters, you gain 1 life.
To solve — You've gained 5 or more life this turn. (If unsolved, solve at the beginning of your end step.)
Solved — Sacrifice this Case: Creature cards in your graveyard gain "You may cast this card from your graveyard" until end of turn.

Choice of Damnations

Target opponent chooses a number. You may have that player lose that much life. If you don't, that player sacrifices all but that many permanents of their choice.

Ghastly Gloomhunter

Kicker {3}{B} (You may pay an additional {3}{B} as you cast this spell.)
Flying, lifelink
If Ghastly Gloomhunter was kicked, it enters with two +1/+1 counters on it.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Serene Offering

Destroy target enchantment. You gain life equal to its mana value.

Queza, Augur of Agonies

Whenever you draw a card, target opponent loses 1 life and you gain 1 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Kambal, Profiteering Mayor

Whenever one or more tokens your opponents control enter, for each of them, create a tapped token that's a copy of it. This ability triggers only once each turn.
Whenever one or more tokens you control enter, each opponent loses 1 life and you gain 1 life.

Ancient Cellarspawn

Each spell you cast that's a Demon, Horror, or Nightmare costs {1} less to cast.
Whenever you cast a spell, if the amount of mana spent to cast it was less than its mana value, target opponent loses life equal to the difference.

Ukkima, Stalking Shadow

Partner with Cazur, Ruthless Stalker (When this creature enters, target player may put Cazur into their hand from their library, then shuffle.)
Ukkima, Stalking Shadow can't be blocked.
When Ukkima leaves the battlefield, it deals X damage to target player and you gain X life, where X is its power.

Mirkwood Bats

Flying
Whenever you create or sacrifice a token, each opponent loses 1 life.

Hammer of Nazahn

Whenever Hammer of Nazahn or another Equipment you control enters, you may attach that Equipment to target creature you control.
Equipped creature gets +2/+0 and has indestructible.
Equip {4}

Bloodhunter Bat

Flying
When Bloodhunter Bat enters, target player loses 2 life and you gain 2 life.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Bishop's Soldier

Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Exalted Angel

Flying
Whenever Exalted Angel deals damage, you gain that much life.
Morph {2}{W}{W} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Savage Gorger

Flying
At the beginning of your end step, if an opponent lost life this turn, put a +1/+1 counter on Savage Gorger. (Damage causes loss of life.)

Fiendish Panda

Whenever you gain life, put a +1/+1 counter on this creature.
When this creature dies, return another target non-Bear creature card with mana value less than or equal to this creature's power from your graveyard to the battlefield.

Locthwain Scorn

Target creature gets -3/-3 until end of turn. You gain 2 life.

Virtue of Persistence

At the beginning of your upkeep, put target creature card from a graveyard onto the battlefield under your control.

Virtue of Persistence // Locthwain Scorn

Essence Harvest

Target player loses X life and you gain X life, where X is the greatest power among creatures you control.

The Broken Sky

Creature tokens you control get +1/+0 and have lifelink.
At the beginning of your end step, create a 1/1 white and black Spirit creature token with flying.

Invasion of Tolvada

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When Invasion of Tolvada enters, return target nonbattle permanent card from your graveyard to the battlefield.

Invasion of Tolvada // The Broken Sky

Cat Collector

When this creature enters, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")
Whenever you gain life for the first time during each of your turns, create a 1/1 white Cat creature token.

Staff of the Death Magus

Whenever you cast a black spell or a Swamp you control enters, you gain 1 life.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Wispdrinker Vampire

Flying
Whenever another creature you control with power 2 or less enters, each opponent loses 1 life and you gain 1 life.
{5}{W}{B}: Creatures you control with power 2 or less gain deathtouch and lifelink until end of turn.

Malakir Familiar

Flying, deathtouch
Whenever you gain life, Malakir Familiar gets +1/+1 until end of turn.

Kaya, Geist Hunter

+1: Creatures you control gain deathtouch until end of turn. Put a +1/+1 counter on up to one target creature token you control.
−2: Until end of turn, if one or more tokens would be created under your control, twice that many of those tokens are created instead.
−6: Exile all cards from all graveyards, then create a 1/1 white Spirit creature token with flying for each card exiled this way.

Vito, Fanatic of Aclazotz

Flying
Whenever you sacrifice another permanent, you gain 2 life if this is the first time this ability has resolved this turn. If it's the second time, each opponent loses 2 life. If it's the third time, create a 4/3 white and black Vampire Demon creature token with flying.

Agate-Blade Assassin

Whenever Agate-Blade Assassin attacks, defending player loses 1 life and you gain 1 life.

Starseer Mentor

Flying, vigilance
At the beginning of your end step, if you gained or lost life this turn, target opponent loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.

Vraan, Executioner Thane

Whenever one or more other creatures you control die, each opponent loses 2 life and you gain 2 life. This ability triggers only once each turn.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Sunscorch Regent

Flying
Whenever an opponent casts a spell, put a +1/+1 counter on Sunscorch Regent and you gain 1 life.

Fleshtaker

Whenever you sacrifice another creature, you gain 1 life and scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{1}, Sacrifice another creature: Fleshtaker gets +2/+2 until end of turn.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Elenda, Saint of Dusk

Lifelink, hexproof from instants
As long as your life total is greater than your starting life total, Elenda gets +1/+1 and has menace. Elenda gets an additional +5/+5 as long as your life total is at least 10 greater than your starting life total.

Adarkar Wastes

{T}: Add {C}.
{T}: Add {W} or {U}. Adarkar Wastes deals 1 damage to you.

Zoraline, Cosmos Caller

Flying, vigilance
Whenever a Bat you control attacks, you gain 1 life.
Whenever Zoraline enters or attacks, you may pay {W}{B} and 2 life. When you do, return target nonland permanent card with mana value 3 or less from your graveyard to the battlefield with a finality counter on it.