Risk Factor

Target opponent may have Risk Factor deal 4 damage to them. If that player doesn't, you draw three cards.
Jump-start (You may cast this card from your graveyard by discarding a card in addition to paying its other costs. Then exile this card.)

Misers' Cage

At the beginning of each opponent's upkeep, if that player has five or more cards in hand, this artifact deals 2 damage to that player.

Browbeat

Any player may have Browbeat deal 5 damage to them. If no one does, target player draws three cards.

Valgavoth, Harrower of Souls

Flying
Ward—Pay 2 life.
Whenever an opponent loses life for the first time during each of their turns, put a +1/+1 counter on Valgavoth and draw a card.

Spellshock

Whenever a player casts a spell, this enchantment deals 2 damage to that player.

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Mana Geyser

Add {R} for each tapped land your opponents control.

Pain Distributor

Menace
Whenever a player casts their first spell each turn, they create a Treasure token.
Whenever an artifact an opponent controls is put into a graveyard from the battlefield, this creature deals 1 damage to that player.

Marchesa's Decree

When this enchantment enters, you become the monarch.
Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Ivory Tower

At the beginning of your upkeep, you gain X life, where X is the number of cards in your hand minus 4.

Kazuul, Tyrant of the Cliffs

Whenever a creature an opponent controls attacks, if you're the defending player, create a 3/3 red Ogre creature token unless that creature's controller pays {3}.

Price of Knowledge

Players have no maximum hand size.
At the beginning of each opponent's upkeep, this enchantment deals damage to that player equal to the number of cards in that player's hand.

Calculating Lich

Menace
Whenever a creature attacks one of your opponents, that player loses 1 life.

Lethal Vapors

Whenever a creature enters, destroy it.
{0}: Destroy this enchantment. You skip your next turn. Any player may activate this ability.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Chain Reaction

Chain Reaction deals X damage to each creature, where X is the number of creatures on the battlefield.

Cunning Rhetoric

Whenever an opponent attacks you and/or one or more planeswalkers you control, exile the top card of that player's library. You may play that card for as long as it remains exiled, and you may spend mana as though it were mana of any color to cast it.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Disrupt Decorum

Goad all creatures you don't control. (Until your next turn, those creatures attack each combat if able and attack a player other than you if able.)

Manabarbs

Whenever a player taps a land for mana, this enchantment deals 1 damage to that player.

Roiling Vortex

At the beginning of each player's upkeep, this enchantment deals 1 damage to them.
Whenever a player casts a spell, if no mana was spent to cast that spell, this enchantment deals 5 damage to that player.
{R}: Your opponents can't gain life this turn.

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Gixian Puppeteer

Whenever you draw your second card each turn, each opponent loses 2 life and you gain 2 life.
When this creature dies, return another target creature card with mana value 3 or less from your graveyard to the battlefield.