Sign in Blood

Target player draws two cards and loses 2 life.

Bayou

Ezio, Blade of Vengeance

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Whenever an Assassin you control deals combat damage to a player, draw a card.

Callidus Assassin

Flash
Polymorphine — You may have Callidus Assassin enter tapped as a copy of any creature on the battlefield, except it has "When this creature enters, destroy up to one other target creature with the same name as this creature."

Vraska, Golgari Queen

+2: You may sacrifice another permanent. If you do, you gain 1 life and draw a card.
−3: Destroy target nonland permanent with mana value 3 or less.
−9: You get an emblem with "Whenever a creature you control deals combat damage to a player, that player loses the game."

Island

Verdant Catacombs

{T}, Pay 1 life, Sacrifice Verdant Catacombs: Search your library for a Swamp or Forest card, put it onto the battlefield, then shuffle.

Underground Sea

Chrome Mox

Imprint — When Chrome Mox enters, you may exile a nonartifact, nonland card from your hand.
{T}: Add one mana of any of the exiled card's colors.

Honest Rutstein

When Honest Rutstein enters, return target creature card from your graveyard to your hand.
Creature spells you cast cost {1} less to cast.

Cavern of Souls

As Cavern of Souls enters, choose a creature type.
{T}: Add {C}.
{T}: Add one mana of any color. Spend this mana only to cast a creature spell of the chosen type, and that spell can't be countered.

Big Game Hunter

When Big Game Hunter enters, destroy target creature with power 4 or greater. It can't be regenerated.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Forest

Assassin's Trophy

Destroy target permanent an opponent controls. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Kaito Shizuki

At the beginning of your end step, if Kaito Shizuki entered this turn, he phases out.
+1: Draw a card. Then discard a card unless you attacked this turn.
−2: Create a 1/1 blue Ninja creature token with "This creature can't be blocked."
−7: You get an emblem with "Whenever a creature you control deals combat damage to a player, search your library for a blue or black creature card, put it onto the battlefield, then shuffle."

Polluted Delta

{T}, Pay 1 life, Sacrifice Polluted Delta: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Swamp

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Nekrataal

First strike
When Nekrataal enters, destroy target nonartifact, nonblack creature. That creature can't be regenerated.

Vraska, the Silencer

Deathtouch
Whenever a nontoken creature an opponent controls dies, you may pay {1}. If you do, return that card to the battlefield tapped under your control. It's a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color," and it loses all other card types.