Anowon, the Ruin Sage

At the beginning of your upkeep, each player sacrifices a non-Vampire creature of their choice.

Descent into Madness

At the beginning of your upkeep, put a despair counter on this enchantment, then each player exiles X permanents they control and/or cards from their hand, where X is the number of despair counters on this enchantment.

Possessed Portal

If a player would draw a card, that player skips that draw instead.
At the beginning of each end step, each player sacrifices a permanent of their choice unless they discard a card.

Molder Slug

At the beginning of each player's upkeep, that player sacrifices an artifact of their choice.

Woebringer Demon

Flying
At the beginning of each player's upkeep, that player sacrifices a creature of their choice. If the player can't, sacrifice this creature.

Smokestack

At the beginning of your upkeep, you may put a soot counter on this artifact.
At the beginning of each player's upkeep, that player sacrifices a permanent of their choice for each soot counter on this artifact.

Magus of the Abyss

At the beginning of each player's upkeep, destroy target nonartifact creature that player controls of their choice. It can't be regenerated.

Mana Vortex

When you cast this spell, counter it unless you sacrifice a land.
At the beginning of each player's upkeep, that player sacrifices a land of their choice.
When there are no lands on the battlefield, sacrifice this enchantment.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Destructive Flow

At the beginning of each player's upkeep, that player sacrifices a nonbasic land of their choice.

Defiler of Souls

Flying
At the beginning of each player's upkeep, that player sacrifices a monocolored creature of their choice.

Braids, Cabal Minion

At the beginning of each player's upkeep, that player sacrifices an artifact, creature, or land of their choice.

World Queller

At the beginning of your upkeep, you may choose a card type. If you do, each player sacrifices a permanent of their choice of that type.

Desolation

At the beginning of each end step, each player who tapped a land for mana this turn sacrifices a land of their choice. This enchantment deals 2 damage to each player who sacrificed a Plains this way.

Porphyry Nodes

At the beginning of your upkeep, destroy the creature with the least power. It can't be regenerated. If two or more creatures are tied for least power, you choose one of them.
When there are no creatures on the battlefield, sacrifice this enchantment.

Call to the Grave

At the beginning of each player's upkeep, that player sacrifices a non-Zombie creature of their choice.
At the beginning of the end step, if no creatures are on the battlefield, sacrifice this enchantment.

The Abyss

Doom Foretold

At the beginning of each player's upkeep, that player sacrifices a nonland, nontoken permanent of their choice. If that player can't, they discard a card, they lose 2 life, you draw a card, you gain 2 life, you create a 2/2 white Knight creature token with vigilance, then you sacrifice this enchantment.

Drop of Honey

Dystopia

Cumulative upkeep—Pay 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
At the beginning of each player's upkeep, that player sacrifices a green or white permanent of their choice.

Culling Scales

At the beginning of your upkeep, destroy target nonland permanent with the lowest mana value. (If two or more permanents are tied for lowest, target any one of them.)

Ruthless Winnower

At the beginning of each player's upkeep, that player sacrifices a non-Elf creature of their choice.