Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Mangara, the Diplomat

Lifelink
Whenever an opponent attacks with creatures, if two or more of those creatures are attacking you and/or planeswalkers you control, draw a card.
Whenever an opponent casts their second spell each turn, draw a card.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Grand Abolisher

During your turn, your opponents can't cast spells or activate abilities of artifacts, creatures, or enchantments.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Lim-Dûl's Vault

Look at the top five cards of your library. As many times as you choose, you may pay 1 life, put those cards on the bottom of your library in any order, then look at the top five cards of your library. Then shuffle and put the last cards you looked at this way on top in any order.

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Dimir Signet

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Greater Auramancy

Other enchantments you control have shroud. (A permanent with shroud can't be the target of spells or abilities.)
Enchanted creatures you control have shroud.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Mystical Tutor

Search your library for an instant or sorcery card, reveal it, then shuffle and put that card on top.

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Mistgate Pathway

Hengegate Pathway

Hengegate Pathway // Mistgate Pathway

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Sea of Clouds

Sea of Clouds enters tapped unless you have two or more opponents.
{T}: Add {W} or {U}.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Pact of Negation

Counter target spell.
At the beginning of your next upkeep, pay {3}{U}{U}. If you don't, you lose the game.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Vile Consumption

All creatures have "At the beginning of your upkeep, sacrifice this creature unless you pay 1 life."

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Counterspell

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Serra's Sanctum

{T}: Add {W} for each enchantment you control.

Mana Drain

Counter target spell. At the beginning of your next main phase, add an amount of {C} equal to that spell's mana value.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Mystic Remora

Cumulative upkeep {1} (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
Whenever an opponent casts a noncreature spell, you may draw a card unless that player pays {4}.

Azorius Signet

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Words of Worship

{1}: The next time you would draw a card this turn, you gain 5 life instead.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Plains

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Volrath's Stronghold

{T}: Add {C}.
{1}{B}, {T}: Put target creature card from your graveyard on top of your library.

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.

Swamp

Talisman of Progress

{T}: Add {C}.
{T}: Add {W} or {U}. Talisman of Progress deals 1 damage to you.

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Island

Swan Song

Counter target enchantment, instant, or sorcery spell. Its controller creates a 2/2 blue Bird creature token with flying.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is Esper Sentinel's power.

Angel of Destiny

Flying, double strike
Whenever a creature you control deals combat damage to a player, you and that player each gain that much life.
At the beginning of your end step, if you have at least 15 life more than your starting life total, each player Angel of Destiny attacked this turn loses the game.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Murkwater Pathway

Clearwater Pathway

Clearwater Pathway // Murkwater Pathway

Ghostly Prison

Flooded Strand

{T}, Pay 1 life, Sacrifice Flooded Strand: Search your library for a Plains or Island card, put it onto the battlefield, then shuffle.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Replenish

Return all enchantment cards from your graveyard to the battlefield. (Auras with nothing to enchant remain in your graveyard.)

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Orzhov Signet

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters, you may pay 2 life. If you don't, it enters tapped.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Hallowed Fountain

({T}: Add {W} or {U}.)
As Hallowed Fountain enters, you may pay 2 life. If you don't, it enters tapped.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Felidar Sovereign

Vigilance (Attacking doesn't cause this creature to tap.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Hall of Heliod's Generosity

{T}: Add {C}.
{1}{W}, {T}: Put target enchantment card from your graveyard on top of your library.

Reliquary Tower

Mirrormade

You may have Mirrormade enter as a copy of any artifact or enchantment on the battlefield.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Fetid Heath

{T}: Add {C}.
{W/B}, {T}: Add {W}{W}, {W}{B}, or {B}{B}.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Dovin's Veto

This spell can't be countered.
Counter target noncreature spell.

Dakkon, Shadow Slayer

Dakkon, Shadow Slayer enters with a number of loyalty counters on him equal to the number of lands you control.
+1: Surveil 2.
−3: Exile target creature.
−6: You may put an artifact card from your hand or graveyard onto the battlefield.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Polluted Delta

{T}, Pay 1 life, Sacrifice Polluted Delta: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Emergence Zone

{T}: Add {C}.
{1}, {T}, Sacrifice Emergence Zone: You may cast spells this turn as though they had flash.

Mystic Gate

{T}: Add {C}.
{W/U}, {T}: Add {W}{W}, {W}{U}, or {U}{U}.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Buried Ruin

{T}: Add {C}.
{2}, {T}, Sacrifice Buried Ruin: Return target artifact card from your graveyard to your hand.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Damnation

Destroy all creatures. They can't be regenerated.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Arcane Signet

Sol Ring

Sunken Ruins

{T}: Add {C}.
{U/B}, {T}: Add {U}{U}, {U}{B}, or {B}{B}.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Grimclimb Pathway

Brightclimb Pathway

Brightclimb Pathway // Grimclimb Pathway

Glacial Fortress

Glacial Fortress enters tapped unless you control a Plains or an Island.
{T}: Add {W} or {U}.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature of their choice and you return up to one target creature card from your graveyard to your hand.