one for multiple

Call Forth the Tempest

Cascade, cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom of your library in a random order. Then do it again.)
Call Forth the Tempest deals damage to each creature your opponents control equal to the total mana value of other spells you've cast this turn.

Extinction

Destroy all creatures of the creature type of your choice.

Unexplained Absence

For each player, exile up to one target nonland permanent that player controls. For each permanent exiled this way, its controller cloaks the top card of their library. (To cloak a card, put it onto the battlefield face down as a 2/2 creature with ward {2}. Turn it face up any time for its mana cost if it's a creature card.)

Luminate Primordial

Vigilance
When this creature enters, for each opponent, exile up to one target creature that player controls and that player gains life equal to its power.

Single target removal

Seal of Removal

Sacrifice this enchantment: Return target creature to its owner's hand.

Casualties of War

Choose one or more —
• Destroy target artifact.
• Destroy target creature.
• Destroy target enchantment.
• Destroy target land.
• Destroy target planeswalker.

Apex Altisaur

When this creature enters, it fights up to one target creature you don't control.
Enrage — Whenever this creature is dealt damage, it fights up to one target creature you don't control.

Guff Rewrites History

For each player, choose target nonenchantment, nonland permanent that player controls. Those permanents' owners shuffle them into their libraries. Each player who controlled one of those permanents exiles cards from the top of their library until they exile a nonland card, then puts the rest on the bottom of their library in a random order. Each player may cast the nonland card they exiled without paying its mana cost.

Plant Tadpoles

Tap X target creatures. They don't untap during their controllers' next untap steps. (Then exile this card. You may cast the creature later from exile.)

Illithid Harvester

Ceremorphosis — When this creature enters, turn any number of target tapped nontoken creatures face down. They're 2/2 Horror creatures.

Illithid Harvester // Plant Tadpoles

Ondu Skyruins

Board wipes

Ondu Inversion

Ondu Inversion // Ondu Skyruins

Planar Cleansing

The Rollercrusher Ride

Delirium — If a source you control would deal noncombat damage to a permanent or player while there are four or more card types among cards in your graveyard, it deals double that damage instead.
When The Rollercrusher Ride enters, it deals X damage to each of up to X target creatures.

Yahenni's Expertise

All creatures get -3/-3 until end of turn.
You may cast a spell with mana value 3 or less from your hand without paying its mana cost.

Tragic Arrogance

For each player, you choose from among the permanents that player controls an artifact, a creature, an enchantment, and a planeswalker. Then each player sacrifices all other nonland permanents they control.

Waltz of Rage

Target creature you control deals damage equal to its power to each other creature. Until end of turn, whenever a creature you control dies, exile the top card of your library. You may play it until the end of your next turn.

Ram Through

Target creature you control deals damage equal to its power to target creature you don't control. If the creature you control has trample, excess damage is dealt to that creature's controller instead.

Void Rend

This spell can't be countered.
Destroy target nonland permanent.

Wave of Vitriol

Each player sacrifices all artifacts, enchantments, and nonbasic lands they control. For each land sacrificed this way, its controller may search their library for a basic land card and put it onto the battlefield tapped. Then each player who searched their library this way shuffles.

Fleshbag Marauder

When this creature enters, each player sacrifices a creature of their choice.

Nature's Ruin

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Crush of Tentacles

Surge {3}{U}{U} (You may cast this spell for its surge cost if you or a teammate has cast another spell this turn.)
Return all nonland permanents to their owners' hands. If this spell's surge cost was paid, create an 8/8 blue Octopus creature token.

Plague Wind

Destroy all creatures you don't control. They can't be regenerated.

Windgrace's Judgment

For any number of opponents, destroy target nonland permanent that player controls.

Beast Within

Destroy target permanent. Its controller creates a 3/3 green Beast creature token.

Volcanic Fallout

This spell can't be countered.
Volcanic Fallout deals 2 damage to each creature and each player.

Culling Ritual

Destroy each nonland permanent with mana value 2 or less. Add {B} or {G} for each permanent destroyed this way.

Return to Dust

Exile target artifact or enchantment. If you cast this spell during your main phase, you may exile up to one other target artifact or enchantment.

Fiery Confluence

Choose three. You may choose the same mode more than once.
• Fiery Confluence deals 1 damage to each creature.
• Fiery Confluence deals 2 damage to each opponent.
• Destroy target artifact.

Devastation Tide

Return all nonland permanents to their owners' hands.
Miracle {1}{U} (You may cast this card for its miracle cost when you draw it if it's the first card you drew this turn.)

Repeatable single target removal

Kogla, the Titan Ape

When Kogla enters, it fights up to one target creature you don't control.
Whenever Kogla attacks, destroy target artifact or enchantment defending player controls.
{1}{G}: Return target Human you control to its owner's hand. Kogla gains indestructible until end of turn.

Boseiju, Who Endures

{T}: Add {G}.
Channel — {1}{G}, Discard this card: Destroy target artifact, enchantment, or nonbasic land an opponent controls. That player may search their library for a land card with a basic land type, put it onto the battlefield, then shuffle. This ability costs {1} less to activate for each legendary creature you control.

Kitesail Larcenist

Flying, ward {1}
When this creature enters, for each player, choose up to one other target artifact or creature that player controls. For as long as this creature remains on the battlefield, the chosen permanents become Treasure artifacts with "{T}, Sacrifice this artifact: Add one mana of any color" and lose all other abilities.

Reality Shift

Exile target creature. Its controller manifests the top card of their library. (That player puts the top card of their library onto the battlefield face down as a 2/2 creature. If it's a creature card, it can be turned face up any time for its mana cost.)

Curtains' Call

Undaunted (This spell costs {1} less to cast for each opponent.)
Destroy two target creatures.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Dictate of Erebos

Flash
Whenever a creature you control dies, each opponent sacrifices a creature of their choice.

Storm's Wrath

Storm's Wrath deals 4 damage to each creature and each planeswalker.

Ritual of Soot

Destroy all creatures with mana value 3 or less.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Creeping Corrosion

Fade Away

For each creature, its controller sacrifices a permanent of their choice unless they pay {1}.

Terastodon

When this creature enters, you may destroy up to three target noncreature permanents. For each permanent put into a graveyard this way, its controller creates a 3/3 green Elephant creature token.

Seal of Doom

Sacrifice this enchantment: Destroy target nonblack creature. It can't be regenerated.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Rout

You may cast this spell as though it had flash if you pay {2} more to cast it. (You may cast it any time you could cast an instant.)
Destroy all creatures. They can't be regenerated.

Solitude

Flash
Lifelink
When this creature enters, exile up to one other target creature. That creature's controller gains life equal to its power.
Evoke—Exile a white card from your hand.

Biting Rain

All creatures get -2/-2 until end of turn.
Madness {2}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Pyroclasm

Pyroclasm deals 2 damage to each creature.

Slash the Ranks

Destroy all creatures and planeswalkers except for commanders.

Tumble

Tumble deals 6 damage to each creature with flying.

Rough

Rough deals 2 damage to each creature without flying.

Rough // Tumble

Thunderwave

Roll a d20.
1—9 | Thunderwave deals 3 damage to each creature.
10—19 | You may choose a creature. Thunderwave deals 3 damage to each creature not chosen this way.
20 | Thunderwave deals 6 damage to each creature your opponents control.

Structural Assault

Destroy all artifacts, then Structural Assault deals damage to each creature equal to the number of artifacts that were put into graveyards from the battlefield this turn.

Delayed Blast Fireball

Delayed Blast Fireball deals 2 damage to each opponent and each creature they control. If this spell was cast from exile, it deals 5 damage to each opponent and each creature they control instead.
Foretell {4}{R}{R} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Comet Storm

Multikicker {1} (You may pay an additional {1} any number of times as you cast this spell.)
Choose any target, then choose another target for each time this spell was kicked. Comet Storm deals X damage to each of them.

Desynchronization

Return each nonland permanent that's not historic to its owner's hand. (Artifacts, legendaries, and Sagas are historic.)

Primeval Light

Destroy all enchantments target player controls.

Benalish Sleeper

Kicker {B} (You may pay an additional {B} as you cast this spell.)
When this creature enters, if it was kicked, each player sacrifices a creature of their choice.

Decimate

Destroy target artifact, target creature, target enchantment, and target land. (You can't cast this spell unless you have legal choices for all its targets.)

Mizzium Mortars

Mizzium Mortars deals 4 damage to target creature you don't control.
Overload {3}{R}{R}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Terminate

Destroy target creature. It can't be regenerated.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Season of Weaving

Choose up to five {P} worth of modes. You may choose the same mode more than once.
{P} — Draw a card.
{P}{P} — Choose an artifact or creature you control. Create a token that's a copy of it.
{P}{P}{P} — Return each nonland, nontoken permanent to its owner's hand.

Cloudkill

All creatures get -X/-X until end of turn, where X is the greatest mana value of a commander you own on the battlefield or in the command zone.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle this card, all creatures get -2/-2 until end of turn.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Crisis of Conscience

Choose one —
• Destroy all tokens.
• Destroy all nonland, nontoken permanents.

Chain of Vapor

Return target nonland permanent to its owner's hand. Then that permanent's controller may sacrifice a land of their choice. If the player does, they may copy this spell and may choose a new target for that copy.

Infest

All creatures get -2/-2 until end of turn.

Urgent Necropsy

As an additional cost to cast this spell, collect evidence X, where X is the total mana value of the permanents this spell targets.
Destroy up to one target artifact, up to one target creature, up to one target enchantment, and up to one target planeswalker.

Wave Goodbye

Return each creature without a +1/+1 counter on it to its owner's hand.

Play of the Game

Assist (Another player can pay up to {6} of this spell's cost.)
Exile all nonland permanents.

Urza's Ruinous Blast

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Exile all nonland permanents that aren't legendary.

Leadership Vacuum

Target player returns each commander they control from the battlefield to the command zone.
Draw a card.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice this enchantment.
{B}: This enchantment deals 1 damage to each creature and each player.

Flame Sweep

Flame Sweep deals 2 damage to each creature except for creatures you control with flying.

Cry of the Carnarium

All creatures get -2/-2 until end of turn. Exile all creature cards in all graveyards that were put there from the battlefield this turn. If a creature would die this turn, exile it instead.

Virtue's Ruin

The Curse of Fenric

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — For each player, destroy up to one target creature that player controls. For each creature destroyed this way, its controller creates a 3/3 green Mutant creature token with deathtouch.
II — Target nontoken creature becomes a 6/6 legendary Horror creature named Fenric and loses all abilities.
III — Target Mutant fights another target creature named Fenric.

Seal of Cleansing

Sacrifice this enchantment: Destroy target artifact or enchantment.

Aura of Silence

Artifact and enchantment spells your opponents cast cost {2} more to cast.
Sacrifice this enchantment: Destroy target artifact or enchantment.

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

Infernal Grasp

Destroy target creature. You lose 2 life.

Bane of the Living

Morph {X}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)
When this creature is turned face up, all creatures get -X/-X until end of turn.

Setessan Tactics

Strive — This spell costs {G} more to cast for each target beyond the first.
Until end of turn, any number of target creatures each get +1/+1 and gain "{T}: This creature fights another target creature."

Stroke of Midnight

Destroy target nonland permanent. Its controller creates a 1/1 white Human creature token.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Elspeth, Sun's Champion

+1: Create three 1/1 white Soldier creature tokens.
−3: Destroy all creatures with power 4 or greater.
−7: You get an emblem with "Creatures you control get +2/+2 and have flying."

Dawn

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Return all creature cards with power 2 or less from your graveyard to your hand.

Dusk

Destroy all creatures with power 3 or greater.

Dusk // Dawn

Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)

Windstorm

Windstorm deals X damage to each creature with flying.

Their Name Is Death

Reality Spasm

Choose one —
• Tap X target permanents.
• Untap X target permanents.

Reign of Terror

Destroy all green creatures or all white creatures. They can't be regenerated. You lose 2 life for each creature that died this way.

Delete

Delete deals X damage to each nonartifact creature and each player.