Rankle's Prank

Choose one or more —
• Each player discards two cards.
• Each player loses 4 life.
• Each player sacrifices two creatures of their choice.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with this creature's toughness.

Wretched Confluence

Choose three. You may choose the same mode more than once.
• Target player draws a card and loses 1 life.
• Target creature gets -2/-2 until end of turn.
• Return target creature card from your graveyard to your hand.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Death Cloud

Each player loses X life, discards X cards, sacrifices X creatures of their choice, then sacrifices X lands of their choice.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Bitter Triumph

As an additional cost to cast this spell, discard a card or pay 3 life.
Destroy target creature or planeswalker.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Charcoal Diamond

This artifact enters tapped.
{T}: Add {B}.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Sign in Blood

Target player draws two cards and loses 2 life.

Price of Knowledge

Players have no maximum hand size.
At the beginning of each opponent's upkeep, this enchantment deals damage to that player equal to the number of cards in that player's hand.

Thought Vessel

Temple Bell

Foreboding Fruit

Target player draws two cards and loses 2 life.
Adamant — If at least three black mana was spent to cast this spell, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")

Howling Banshee

Flying
When this creature enters, each player loses 3 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Vendetta

Destroy target nonblack creature. It can't be regenerated. You lose life equal to that creature's toughness.

Scourge of the Skyclaves

Kicker {4}{B}
When you cast this spell, if it was kicked, each player loses half their life, rounded up.
Scourge of the Skyclaves's power and toughness are each equal to 20 minus the highest life total among players.

Dark Ritual

Gray Merchant of Asphodel

When this creature enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Fell Stinger

Deathtouch
Exploit (When this creature enters, you may sacrifice a creature.)
When this creature exploits a creature, target player draws two cards and loses 2 life.

Leaden Myr

Coveted Jewel

When this artifact enters, draw three cards.
{T}: Add three mana of any one color.
Whenever one or more creatures an opponent controls attack you and aren't blocked, that player draws three cards and gains control of this artifact. Untap it.

Emissary of Despair

Flying
Whenever this creature deals combat damage to a player, that player loses 1 life for each artifact they control.

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Sol Ring

Aurora of Emrakul

Flying, deathtouch
Whenever this creature attacks, each opponent loses 3 life.

Cryptolith Fragment

This artifact enters tapped.
{T}: Add one mana of any color. Each player loses 1 life.
At the beginning of your upkeep, if each player has 10 or less life, transform this artifact.

Cryptolith Fragment // Aurora of Emrakul

Kokusho, the Evening Star

Flying
When Kokusho dies, each opponent loses 5 life. You gain life equal to the life lost this way.

Infernal Grasp

Destroy target creature. You lose 2 life.

Dire Fleet Ravager

Menace, deathtouch
When this creature enters, each player loses a third of their life, rounded up.

Scrawling Crawler

At the beginning of your upkeep, each player draws a card.
Whenever an opponent draws a card, that player loses 1 life.

Ornithopter of Paradise

Bellowing Mauler

At the beginning of your end step, each player loses 4 life unless they sacrifice a nontoken creature of their choice.

Skirsdag Supplicant

{B}, {T}, Discard a card: Each player loses 2 life.

Fraying Omnipotence

Each player loses half their life, then discards half the cards in their hand, then sacrifices half the creatures they control of their choice. Round up each time.

Fate Unraveler

Whenever an opponent draws a card, this creature deals 1 damage to that player.

Stronghold Discipline

Each player loses 1 life for each creature they control.

Zenith Chronicler

Whenever a player casts their first multicolored spell each turn, each other player draws a card.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Bad Deal

You draw two cards and each opponent discards two cards. Each player loses 2 life.

Killing Wave

For each creature, its controller sacrifices it unless they pay X life.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Howling Mine

At the beginning of each player's draw step, if this artifact is untapped, that player draws an additional card.

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Rabid Bloodsucker

Flying (This creature can't be blocked except by creatures with flying or reach.)
When this creature enters, each player loses 2 life.

Swamp

Iron Maiden

At the beginning of each opponent's upkeep, this artifact deals X damage to that player, where X is the number of cards in their hand minus 4.

Devour in Shadow

Destroy target creature. It can't be regenerated. You lose life equal to that creature's toughness.

Underworld Dreams

Whenever an opponent draws a card, this enchantment deals 1 damage to that player.

Eldritch Pact

Target player draws X cards and loses X life, where X is the number of cards in their graveyard.

Orcish Bowmasters

Flash
When this creature enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, this creature deals 1 damage to any target. Then amass Orcs 1.

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Gilded Lotus

Bond of Agony

As an additional cost to cast this spell, pay X life.
Each other player loses X life.

Greed

Night's Whisper

Soulcage Fiend

When this creature dies, each player loses 3 life.

Damnable Pact

Target player draws X cards and loses X life.

Blood Pact

Fruit of Tizerus

Target player loses 2 life.
Escape—{3}{B}, Exile three other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)