Chain Reaction

Chain Reaction deals X damage to each creature, where X is the number of creatures on the battlefield.

Damning Verdict

Destroy all creatures with no counters on them.

Crisis of Conscience

Choose one —
• Destroy all tokens.
• Destroy all nonland, nontoken permanents.

Massacre Girl

Menace
When Massacre Girl enters, each other creature gets -1/-1 until end of turn. Whenever a creature dies this turn, each creature other than Massacre Girl gets -1/-1 until end of turn.

Split Up

Choose one —
• Destroy all tapped creatures.
• Destroy all untapped creatures.

Aetherspouts

For each attacking creature, its owner puts it on their choice of the top or bottom of their library.

All Is Dust

Each player sacrifices all permanents they control that are one or more colors.

Perplexing Test

Choose one —
• Return all creature tokens to their owners' hands.
• Return all nontoken creatures to their owners' hands.

Culling Ritual

Destroy each nonland permanent with mana value 2 or less. Add {B} or {G} for each permanent destroyed this way.

Hour of Reckoning

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy all nontoken creatures.

Bane of Progress

When this creature enters, destroy all artifacts and enchantments. Put a +1/+1 counter on this creature for each permanent destroyed this way.

Ruinous Ultimatum

Destroy all nonland permanents your opponents control.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Aether Snap

Remove all counters from all permanents and exile all tokens.

Blasphemous Edict

You may pay {B} rather than pay this spell's mana cost if there are thirteen or more creatures on the battlefield.
Each player sacrifices thirteen creatures of their choice.

Time Wipe

Return a creature you control to its owner's hand, then destroy all creatures.

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Ezuri's Predation

For each creature your opponents control, create a 4/4 green Phyrexian Beast creature token. Each of those tokens fights a different one of those creatures.

Raise the Palisade

Choose a creature type. Return all creatures that aren't of the chosen type to their owners' hands.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Filter Out

Return all noncreature, nonland permanents to their owners' hands.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Aetherize

Return all attacking creatures to their owner's hand.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Wave Goodbye

Return each creature without a +1/+1 counter on it to its owner's hand.

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Mandate of Abaddon

Choose target creature you control. Destroy all creatures with power less than that creature's power.

Everything Comes to Dust

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Exile all creatures except those that share a creature type with a creature that convoked this spell, all artifacts, and all enchantments.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Curse of the Swine

Exile X target creatures. For each creature exiled this way, its controller creates a 2/2 green Boar creature token.

Nuclear Fallout

Each creature gets twice -X/-X until end of turn. Each player gets X rad counters.

Vanquish the Horde

This spell costs {1} less to cast for each creature on the battlefield.
Destroy all creatures.

The Battle of Bywater

Destroy all creatures with power 3 or greater. Then create a Food token for each creature you control. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")

Earthquake

Earthquake deals X damage to each creature without flying and each player.

What Must Be Done

Choose one —
• Let the World Burn — Destroy all artifacts and creatures.
• Release Juno — Return target historic permanent card from your graveyard to the battlefield. It enters with two additional +1/+1 counters on it if it's a creature. (Artifacts, legendaries, and Sagas are historic.)

Black Sun's Zenith

Put X -1/-1 counters on each creature. Shuffle Black Sun's Zenith into its owner's library.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Final Showdown

Spree (Choose one or more additional costs.)
+ {1} — All creatures lose all abilities until end of turn.
+ {1} — Choose a creature you control. It gains indestructible until end of turn.
+ {3}{W}{W} — Destroy all creatures.

Evacuation

Return all creatures to their owners' hands.

Dawn

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Return all creature cards with power 2 or less from your graveyard to your hand.

Dusk

Destroy all creatures with power 3 or greater.

Dusk // Dawn

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.