Eye of Vecna

When Eye of Vecna enters, you draw a card and you lose 2 life.
At the beginning of your upkeep, you may pay {2}. If you do, you draw a card and you lose 2 life.

Deadly Dispute

As an additional cost to cast this spell, sacrifice an artifact or creature.
Draw two cards and create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Grave Pact

Whenever a creature you control dies, each other player sacrifices a creature of their choice.

Expedition Map

{2}, {T}, Sacrifice this artifact: Search your library for a land card, reveal it, put it into your hand, then shuffle.

Pact Weapon

As long as this Equipment is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Relic Bane

Enchant artifact
Enchanted artifact has "At the beginning of your upkeep, you lose 2 life."

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Dictate of Erebos

Flash
Whenever a creature you control dies, each opponent sacrifices a creature of their choice.

Don't Have

Magus of the Coffers

{2}, {T}: Add {B} for each Swamp you control.

Castle Locthwain

This land enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Have

Marshland Bloodcaster

Flying
{1}{B}, {T}: Rather than pay the mana cost of the next spell you cast this turn, you may pay life equal to that spell's mana value.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Horizon of Progress

{T}, Pay 1 life: Add one mana of any type that a land you control could produce.
{3}, {T}: You may put a land card from your hand onto the battlefield tapped.
{1}, {T}, Sacrifice this land: Draw a card.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Priest of the Blood Rite

When this creature enters, create a 5/5 black Demon creature token with flying.
At the beginning of your upkeep, you lose 2 life.

Gauntlet of Power

As this artifact enters, choose a color.
Creatures of the chosen color get +1/+1.
Whenever a basic land is tapped for mana of the chosen color, its controller adds an additional one mana of that color.

Worthy Cost

As an additional cost to cast this spell, sacrifice a creature.
Exile target creature or planeswalker.

Death Tyrant

Menace
Negative Energy Cone — Whenever an attacking creature you control or a blocking creature an opponent controls dies, create a 2/2 black Zombie creature token.
{5}{B}: Return this card from your graveyard to the battlefield tapped.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Prismatic Vista

{T}, Pay 1 life, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield, then shuffle.

Dark Ritual

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Gix, Yawgmoth Praetor

Whenever a creature deals combat damage to one of your opponents, its controller may pay 1 life. If they do, they draw a card.
{4}{B}{B}{B}, Discard X cards: Exile the top X cards of target opponent's library. You may play lands and cast spells from among cards exiled this way without paying their mana costs.

Viscera Seer

Sacrifice a creature: Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Creeping Bloodsucker

At the beginning of your upkeep, this creature deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Demolition Field

{T}: Add {C}.
{2}, {T}, Sacrifice this land: Destroy target nonbasic land an opponent controls. That land's controller may search their library for a basic land card, put it onto the battlefield, then shuffle. You may search your library for a basic land card, put it onto the battlefield, then shuffle.

Evolving Wilds

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Dark Prophecy

Whenever a creature you control dies, you draw a card and you lose 1 life.

Ambition's Cost

You draw three cards and you lose 3 life.

Darkness

Prevent all combat damage that would be dealt this turn.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Mask of Griselbrand

Equipped creature has flying and lifelink.
Whenever equipped creature dies, you may pay X life, where X is its power. If you do, draw X cards.
Equip {3}

Whip of Erebos

Creatures you control have lifelink.
{2}{B}{B}, {T}: Return target creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step. If it would leave the battlefield, exile it instead of putting it anywhere else. Activate only as a sorcery.

Caged Sun

As this artifact enters, choose a color.
Creatures you control of the chosen color get +1/+1.
Whenever a land's ability causes you to add one or more mana of the chosen color, add one additional mana of that color.

Raiders' Spoils

Creatures you control get +1/+0.
Whenever a Warrior you control deals combat damage to a player, you may pay 1 life. If you do, draw a card.

Dread Return

Return target creature card from your graveyard to the battlefield.
Flashback—Sacrifice three creatures. (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Thrasher Brute

Whenever this creature or another Warrior your team controls enters, target opponent loses 1 life and you gain 1 life.

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Noxious Gearhulk

Menace
When this creature enters, you may destroy another target creature. If a creature is destroyed this way, you gain life equal to its toughness.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Blood Pact

Target player draws two cards and loses 2 life.

Diresight

Surveil 2, then draw two cards. You lose 2 life. (To surveil 2, look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Insatiable Avarice

Spree (Choose one or more additional costs.)
+ {2} — Search your library for a card, then shuffle and put that card on top.
+ {B}{B} — Target player draws three cards and loses 3 life.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

War Room

{T}: Add {C}.
{3}, {T}, Pay life equal to the number of colors in your commanders' color identity: Draw a card.

City of Brass

Whenever this land becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Mortarion, Daemon Primarch

Flying
Primarch of the Death Guard — At the beginning of your end step, you may pay {X}. If you do, create X 2/2 black Astartes Warrior creature tokens with menace. X can't be greater than the amount of life you lost this turn.

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice this enchantment.
{B}: This enchantment deals 1 damage to each creature and each player.

Archon of Cruelty

Flying
Whenever this creature enters or attacks, target opponent sacrifices a creature or planeswalker of their choice, discards a card, and loses 3 life. You draw a card and gain 3 life.

Mirkwood Bats

Flying
Whenever you create or sacrifice a token, each opponent loses 1 life.

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

Jet Medallion

Black spells you cast cost {1} less to cast.

Force of Despair

If it's not your turn, you may exile a black card from your hand rather than pay this spell's mana cost.
Destroy all creatures that entered this turn.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle this card, all creatures get -2/-2 until end of turn.

Throne of Eldraine

As Throne of Eldraine enters, choose a color.
{T}: Add four mana of the chosen color. Spend this mana only to cast monocolored spells of that color.
{3}, {T}: Draw two cards. Spend only mana of the chosen color to activate this ability.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice this artifact: Draw a card.

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Demonic Gifts

Until end of turn, target creature gets +2/+0 and gains "When this creature dies, return it to the battlefield under its owner's control."

Infernal Sovereign

Flying, trample
Skip your draw step.
Whenever you play a land or cast a spell, you draw a card and you lose 1 life.

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Grinning Demon

At the beginning of your upkeep, you lose 2 life.
Morph {2}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Tragic Slip

Target creature gets -1/-1 until end of turn.
Morbid — That creature gets -13/-13 until end of turn instead if a creature died this turn.

Tallyman of Nurgle

Lifelink
The Seven-fold Chant — At the beginning of your end step, if a creature died this turn, you draw a card and you lose 1 life. If seven or more creatures died this turn, instead you draw seven cards and you lose 7 life.

Séance Board

Morbid — At the beginning of each end step, if a creature died this turn, put a soul counter on this artifact.
{T}: Add X mana of any one color, where X is the number of soul counters on this artifact. Spend this mana only to cast instant, sorcery, Demon, and Spirit spells.

Calculating Lich

Menace
Whenever a creature attacks one of your opponents, that player loses 1 life.

Curse of Fool's Wisdom

Enchant player
Whenever enchanted player draws a card, they lose 2 life and you gain 2 life.
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap this artifact.

Skemfar Shadowsage

When this creature enters, choose one —
• Each opponent loses X life, where X is the greatest number of creatures you control that have a creature type in common.
• You gain X life, where X is the greatest number of creatures you control that have a creature type in common.

Demon's Horn

Whenever a player casts a black spell, you may gain 1 life.

Devour in Shadow

Destroy target creature. It can't be regenerated. You lose life equal to that creature's toughness.

Shard of the Nightbringer

Flying
Drain Life — When this creature enters, if you cast it, target opponent loses half their life, rounded up. You gain life equal to the life lost this way.

Corrupt

Corrupt deals damage to any target equal to the number of Swamps you control. You gain life equal to the damage dealt this way.

Lashwrithe

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +1/+1 for each Swamp you control.
Equip {B/P}{B/P} ({B/P} can be paid with either {B} or 2 life.)

Wayfarer's Bauble

{2}, {T}, Sacrifice this artifact: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Shire Terrace

{T}: Add {C}.
{1}, {T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Swift End

Destroy target creature or planeswalker. You lose 2 life. (Then exile this card. You may cast the creature later from exile.)

Murderous Rider

Lifelink
When this creature dies, put it on the bottom of its owner's library.

Murderous Rider // Swift End

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Ancient Craving

Malakir Mire

Malakir Rebirth

Choose target creature. You lose 2 life. Until end of turn, that creature gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Malakir Rebirth // Malakir Mire

Rust Elemental

Flying
At the beginning of your upkeep, sacrifice another artifact. If you can't, tap this creature and you lose 4 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

The Golden Throne

Arcane Life-support — If you would lose the game, instead exile The Golden Throne and your life total becomes 1.
A Thousand Souls Die Every Day — {T}, Sacrifice a creature: Add three mana in any combination of colors.

Subversion

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Sanguinary Priest

Lifelink
Blood Chalice — Whenever another creature you control dies, this creature deals 1 damage to any target.

Mutilate

All creatures get -1/-1 until end of turn for each Swamp you control.

Bastion of Remembrance

When this enchantment enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Undying Evil

Target creature gains undying until end of turn. (When it dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)

Staff of the Death Magus

Whenever you cast a black spell or a Swamp you control enters, you gain 1 life.

Temple of Aclazotz

(Transforms from Arguel's Blood Fast.)
{T}: Add {B}.
{T}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Arguel's Blood Fast

{1}{B}, Pay 2 life: Draw a card.
At the beginning of your upkeep, if you have 5 or less life, you may transform Arguel's Blood Fast.

Arguel's Blood Fast // Temple of Aclazotz

The Speed Demon

Flying, trample
Start your engines! (If you have no speed, it starts at 1. It increases once on each of your turns when an opponent loses life. Max speed is 4.)
At the beginning of your end step, you draw X cards and lose X life, where X is your speed.

Bile Blight

Target creature and all other creatures with the same name as that creature get -3/-3 until end of turn.