Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature of their choice.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Roiling Vortex

At the beginning of each player's upkeep, this enchantment deals 1 damage to them.
Whenever a player casts a spell, if no mana was spent to cast that spell, this enchantment deals 5 damage to that player.
{R}: Your opponents can't gain life this turn.

Everlasting Torment

Players can't gain life.
Damage can't be prevented.
All damage is dealt as though its source had wither. (A source with wither deals damage to creatures in the form of -1/-1 counters.)

Quakebringer

Your opponents can't gain life.
At the beginning of your upkeep, Quakebringer deals 2 damage to each opponent. This ability triggers only if Quakebringer is on the battlefield or if Quakebringer is in your graveyard and you control a Giant.
Foretell {2}{R}{R}

Suspended Sentence

Destroy target creature an opponent controls. That player loses 3 life. Exile Suspended Sentence with three time counters on it.
Suspend 3—{1}{B} (Rather than cast this card from your hand, you may pay {1}{B} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

Jet Medallion

Black spells you cast cost {1} less to cast.

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

The Fire Crystal

Red spells you cast cost {1} less to cast.
Creatures you control have haste.
{4}{R}{R}, {T}: Create a token that's a copy of target creature you control. Sacrifice it at the beginning of the next end step.

Sunspine Lynx

Players can't gain life.
Damage can't be prevented.
When this creature enters, it deals damage to each player equal to the number of nonbasic lands that player controls.

Pain Magnification

Whenever an opponent is dealt 3 or more damage by a single source, that player discards a card.

The Lord of Pain

Menace
Your opponents can't gain life.
Whenever a player casts their first spell each turn, choose another target player. The Lord of Pain deals damage equal to that spell's mana value to the chosen player.

The Masamune

As long as equipped creature is attacking, it has first strike and must be blocked if able.
Equipped creature has "If a creature dying causes a triggered ability of this creature or an emblem you own to trigger, that ability triggers an additional time."
Equip {2}

Rampaging Ferocidon

Menace
Players can't gain life.
Whenever another creature enters, this creature deals 1 damage to that creature's controller.

Witch Hunt

Players can't gain life.
At the beginning of your upkeep, this enchantment deals 4 damage to you.
At the beginning of your end step, target opponent chosen at random gains control of this enchantment.

Fate Unraveler

Whenever an opponent draws a card, this creature deals 1 damage to that player.

The Rollercrusher Ride

Delirium — If a source you control would deal noncombat damage to a permanent or player while there are four or more card types among cards in your graveyard, it deals double that damage instead.
When The Rollercrusher Ride enters, it deals X damage to each of up to X target creatures.

Call In a Professional

Players can't gain life this turn. Damage can't be prevented this turn. Call In a Professional deals 3 damage to any target. (Shield counters don't prevent this damage as they're removed.)

Stigma Lasher

Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever this creature deals damage to a player, that player can't gain life for the rest of the game.

Grievous Wound

Enchant player
Enchanted player can't gain life.
Whenever enchanted player is dealt damage, they lose half their life, rounded up.

Giant Cindermaw

Trample (This creature can deal excess combat damage to the player or planeswalker it's attacking.)
Players can't gain life.

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Ruby Medallion

Red spells you cast cost {1} less to cast.

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Screaming Nemesis

Haste
Whenever this creature is dealt damage, it deals that much damage to any other target. If a player is dealt damage this way, they can't gain life for the rest of the game.

Sabotender

Reach
Landfall — Whenever a land you control enters, this creature deals 1 damage to each opponent.

Skullcrack

Players can't gain life this turn. Damage can't be prevented this turn. Skullcrack deals 3 damage to target player or planeswalker.

Havoc Festival

Players can't gain life.
At the beginning of each player's upkeep, that player loses half their life, rounded up.

Gríma Wormtongue

Your opponents can't gain life.
{T}, Sacrifice another creature: Target player loses 1 life. If the sacrificed creature was legendary, amass Orcs 2.

The Darkness Crystal

Black spells you cast cost {1} less to cast.
If a nontoken creature an opponent controls would die, instead exile it and you gain 2 life.
{4}{B}{B}, {T}: Put target creature card exiled with The Darkness Crystal onto the battlefield tapped under your control with two additional +1/+1 counters on it.

Leyline of Punishment

If this card is in your opening hand, you may begin the game with it on the battlefield.
Players can't gain life.
Damage can't be prevented.

Harsh Mentor

Whenever an opponent activates an ability of an artifact, creature, or land on the battlefield, if it isn't a mana ability, this creature deals 2 damage to that player.

Tibalt, Rakish Instigator

Your opponents can't gain life.
−2: Create a 1/1 red Devil creature token with "When this token dies, it deals 1 damage to any target."

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Chandra, Awakened Inferno

This spell can't be countered.
+2: Each opponent gets an emblem with "At the beginning of your upkeep, this emblem deals 1 damage to you."
−3: Chandra deals 3 damage to each non-Elemental creature.
−X: Chandra deals X damage to target creature or planeswalker. If a permanent dealt damage this way would die this turn, exile it instead.

Knight of Dusk's Shadow

Menace (This creature can't be blocked except by two or more creatures.)
Your opponents can't gain life.
{1}{B}: This creature gets +1/+1 until end of turn.

Kederekt Parasite

Whenever an opponent draws a card, if you control a red permanent, you may have this creature deal 1 damage to that player.