Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Human

Near-Death Experience

At the beginning of your upkeep, if you have exactly 1 life, you win the game.

Oblivion Ring

When this enchantment enters, exile another target nonland permanent.
When this enchantment leaves the battlefield, return the exiled card to the battlefield under its owner's control.

Death's Shadow

This creature gets -X/-X, where X is your life total.

Last Chance

Take an extra turn after this one. At the beginning of that turn's end step, you lose the game.

Academy Rector

When this creature dies, you may exile it. If you do, search your library for an enchantment card, put that card onto the battlefield, then shuffle.

Cloudsteel Kirin

Flying
Equipped creature has flying and "You can't lose the game and your opponents can't win the game."
Reconfigure {5} ({5}: Attach to target creature you control; or unattach from a creature. Reconfigure only as a sorcery. While attached, this isn't a creature.)

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Enduring Ideal

Search your library for an enchantment card, put it onto the battlefield, then shuffle.
Epic (For the rest of the game, you can't cast spells. At the beginning of each of your upkeeps, copy this spell except for its epic ability.)

One with Nothing

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Tomb of Urami

{T}: Add {B}. Tomb of Urami deals 1 damage to you if you don't control an Ogre.
{2}{B}{B}, {T}, Sacrifice all lands you control: Create Urami, a legendary 5/5 black Demon Spirit creature token with flying.

The Last Ride

The Last Ride gets -X/-X, where X is your life total.
{2}{B}, Pay 2 life: Draw a card.
Crew 2

Chance

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Discard any number of cards, then draw that many cards.

Leave

Return any number of target permanents you own to your hand.

Leave // Chance

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Magus of the Mirror

{T}, Sacrifice this creature: Exchange life totals with target opponent. Activate only during your upkeep.

Break of Day

Creatures you control get +1/+1 until end of turn.
Fateful hour — If you have 5 or less life, those creatures gain indestructible until end of turn. (Damage and effects that say "destroy" don't destroy them.)

Eternity Vessel

This artifact enters with X charge counters on it, where X is your life total.
Landfall — Whenever a land you control enters, you may have your life total become the number of charge counters on this artifact.

Leonin Relic-Warder

When this creature enters, you may exile target artifact or enchantment.
When this creature leaves the battlefield, return the exiled card to the battlefield under its owner's control.

Serra the Benevolent

+2: Creatures you control with flying get +1/+1 until end of turn.
−3: Create a 4/4 white Angel creature token with flying and vigilance.
−6: You get an emblem with "If you control a creature, damage that would reduce your life total to less than 1 reduces it to 1 instead."

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Exquisite Archangel

Flying
If you would lose the game, instead exile this creature and your life total becomes equal to your starting life total.

Lich's Tomb

You don't lose the game for having 0 or less life.
Whenever you lose life, sacrifice a permanent for each 1 life you lost. (Damage causes loss of life.)

Final Fortune

Worship

If you control a creature, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Soul Echo

This enchantment enters with X echo counters on it.
You don't lose the game for having 0 or less life.
At the beginning of your upkeep, sacrifice this enchantment if there are no echo counters on it. Otherwise, target opponent may choose that for each 1 damage that would be dealt to you until your next upkeep, you remove an echo counter from this enchantment instead.

Resilient Wanderer

First strike
Discard a card: This creature gains protection from the color of your choice until end of turn.

Crovax, Ascendant Hero

Other white creatures get +1/+1.
Nonwhite creatures get -1/-1.
Pay 2 life: Return Crovax to its owner's hand.

Skirge Familiar

Decree of Annihilation

Exile all artifacts, creatures, and lands from the battlefield, all cards from all graveyards, and all cards from all hands.
Cycling {5}{R}{R} ({5}{R}{R}, Discard this card: Draw a card.)
When you cycle this card, destroy all lands.

Angelic Enforcer

Flying
You have hexproof.
Angelic Enforcer's power and toughness are each equal to your life total.
Whenever this creature attacks, double your life total.

Enduring Angel

Flying, double strike
You have hexproof.
If your life total would be reduced to 0 or less, instead transform this creature and your life total becomes 3. Then if this creature didn't transform this way, you lose the game.

Enduring Angel // Angelic Enforcer

Infernal Contract

Draw four cards. You lose half your life, rounded up.

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra's power.

Cryptborn Horror

Trample
This creature enters with X +1/+1 counters on it, where X is the total life lost by your opponents this turn.

Loxodon Peacekeeper

At the beginning of your upkeep, the player with the lowest life total gains control of this creature. If two or more players are tied for lowest life total, you choose one of them, and that player gains control of this creature.

Courageous Resolve

Up to one target creature you control gains protection from each of your opponents until end of turn. Draw a card. (It can't be blocked, targeted, dealt damage, enchanted, or equipped by anything controlled by those players.)
Fateful hour — If you have 5 or less life, you can't lose life this turn, you can't lose the game this turn, and your opponents can't win the game this turn.

Gather the Townsfolk

Create two 1/1 white Human creature tokens.
Fateful hour — If you have 5 or less life, create five of those tokens instead.

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Faith's Shield

Target permanent you control gains protection from the color of your choice until end of turn.
Fateful hour — If you have 5 or less life, instead you and each permanent you control gain protection from the color of your choice until end of turn.

Moon-Blessed Cleric

Divine Intervention — When this creature enters, you may search your library for an enchantment card, reveal it, then shuffle and put that card on top.

Tainted Sigil

{T}, Sacrifice this artifact: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Archon of Coronation

Flying
When this creature enters, you become the monarch.
As long as you're the monarch, damage doesn't cause you to lose life. (When a creature deals combat damage to you, its controller still becomes the monarch.)

Vedalken Orrery

You may cast spells as though they had flash.

Convalescent Care

At the beginning of your upkeep, if you have 5 or less life, you gain 3 life and draw a card.

Master of Cruelties

First strike, deathtouch
This creature can only attack alone.
Whenever this creature attacks a player and isn't blocked, that player's life total becomes 1. This creature assigns no combat damage this combat.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Intervention Pact

The next time a source of your choice would deal damage to you this turn, prevent that damage. You gain life equal to the damage prevented this way.
At the beginning of your next upkeep, pay {1}{W}{W}. If you don't, you lose the game.

Emergence Zone

{T}: Add {C}.
{1}, {T}, Sacrifice this land: You may cast spells this turn as though they had flash.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Mirror Universe

{T}, Sacrifice this artifact: Exchange life totals with target opponent. Activate only during your upkeep.

Plunge into Darkness

Choose one —
• Sacrifice any number of creatures. You gain 3 life for each creature sacrificed this way.
• Pay any amount of life, then look at that many cards from the top of your library. Put one of those cards into your hand and exile the rest.
Entwine {B} (Choose both if you pay the entwine cost.)

Renounce

Sacrifice any number of permanents. You gain 2 life for each permanent sacrificed this way.

Fortune Thief

Damage that would reduce your life total to less than 1 reduces it to 1 instead.
Morph {R}{R} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Sustaining Spirit

Cumulative upkeep {1}{W} (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
Damage that would reduce your life total to less than 1 reduces it to 1 instead.

Mages' Contest

You and target spell's controller bid life. You start the bidding with a bid of 1. In turn order, each player may top the high bid. The bidding ends if the high bid stands. The high bidder loses life equal to the high bid. If you win the bidding, counter that spell.

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia to its owner's hand.

Children of Korlis

Sacrifice this creature: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Angel

Kaervek's Spite

As an additional cost to cast this spell, sacrifice all permanents you control and discard your hand.
Target player loses 5 life.

Barren Glory

At the beginning of your upkeep, if you control no permanents other than this enchantment and have no cards in hand, you win the game.

Cruel Bargain

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Avacyn

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: This creature gets +1/+1 until end of turn.

Minion

Glorious End

End the turn. (Exile all spells and abilities from the stack, including this card. The player whose turn it is discards down to their maximum hand size. Damage wears off, and "this turn" and "until end of turn" effects end.)
At the beginning of your next end step, you lose the game.

Transcendence

You don't lose the game for having 0 or less life.
When you have 20 or more life, you lose the game.
Whenever you lose life, you gain 2 life for each 1 life you lost. (Damage dealt to you causes you to lose life.)

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with this creature's toughness.

Greater Gargadon

Suspend 10—{R}
Sacrifice an artifact, creature, or land: Remove a time counter from this card. Activate only if this card is suspended.

Warrior's Oath

Thraben Doomsayer

{T}: Create a 1/1 white Human creature token.
Fateful hour — As long as you have 5 or less life, other creatures you control get +2/+2.

Roiling Horror

Roiling Horror's power and toughness are each equal to your life total minus the life total of an opponent with the most life.
Suspend X—{X}{B}{B}{B}. X can't be 0. (Rather than cast this card from your hand, you may pay {X}{B}{B}{B} and exile it with X time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost. It has haste.)
Whenever a time counter is removed from this card while it's exiled, target player loses 1 life and you gain 1 life.

Fraying Omnipotence

Each player loses half their life, then discards half the cards in their hand, then sacrifices half the creatures they control of their choice. Round up each time.

Platinum Emperion

Your life total can't change. (You can't gain or lose life. You can't pay any amount of life except 0.)

Apocalypse

Exile all permanents. You discard your hand.

Chance for Glory

Creatures you control gain indestructible. Take an extra turn after this one. At the beginning of that turn's end step, you lose the game.

Phyrexian Processor

As this artifact enters, pay any amount of life.
{4}, {T}: Create an X/X black Phyrexian Minion creature token, where X is the life paid as this artifact entered.

Angel of Grace

Flash
Flying
When this creature enters, until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.
{4}{W}{W}, Exile this card from your graveyard: Your life total becomes 10.

Vendetta

Destroy target nonblack creature. It can't be regenerated. You lose life equal to that creature's toughness.

Soulgorger Orgg

Trample
When this creature enters, you lose all but 1 life.
When this creature leaves the battlefield, you gain life equal to the life you lost when it entered.

Horror

Ali from Cairo

Damage that would reduce your life total to less than 1 reduces it to 1 instead.

Hellcarver Demon

Flying
Whenever this creature deals combat damage to a player, sacrifice all other permanents you control and discard your hand. Exile the top six cards of your library. You may cast any number of spells from among cards exiled this way without paying their mana costs.

Worldfire

Exile all permanents. Exile all cards from all hands and graveyards. Each player's life total becomes 1.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Chainer, Nightmare Adept

Discard a card: You may cast a creature spell from your graveyard this turn. Activate only once each turn.
Whenever a nontoken creature you control enters, if you didn't cast it from your hand, it gains haste until your next turn.

The Golden Throne

Arcane Life-support — If you would lose the game, instead exile The Golden Throne and your life total becomes 1.
A Thousand Souls Die Every Day — {T}, Sacrifice a creature: Add three mana in any combination of colors.

Battle at the Helvault

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — For each player, exile up to one target non-Saga, nonland permanent that player controls until this Saga leaves the battlefield.
III — Create Avacyn, a legendary 8/8 white Angel creature token with flying, vigilance, and indestructible.

Gavony Ironwright

Fateful hour — As long as you have 5 or less life, other creatures you control get +1/+4.

Everybody Lives!

All creatures gain hexproof and indestructible until end of turn. Players gain hexproof until end of turn. Players can't lose life this turn and players can't lose the game or win the game this turn.