Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Sorin, Ravenous Neonate

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
+2: Create a Food token.
−1: Sorin deals damage equal to the amount of life you gained this turn to any target.
−6: Gain control of target creature. It becomes a Vampire in addition to its other types. Put a lifelink counter on it if you control a white permanent other than that creature or Sorin.

Sorin of House Markov

Lifelink
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
At the beginning of each of your postcombat main phases, if you gained 3 or more life this turn, exile Sorin, then return him to the battlefield transformed under his owner's control.

Sorin of House Markov // Sorin, Ravenous Neonate

Breena, the Demagogue

Flying
Whenever a player attacks one of your opponents, if that opponent has more life than another of your opponents, that attacking player draws a card and you put two +1/+1 counters on a creature you control.

Dimir House Guard

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Sacrifice a creature: Regenerate this creature.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Syndicate Heavy

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
At the beginning of each end step, if you gained 4 or more life this turn, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this token: Draw a card.")

Healing Salve

Choose one —
• Target player gains 3 life.
• Prevent the next 3 damage that would be dealt to any target this turn.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with this creature's toughness.

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Tonic Peddler

{W}, {T}, Discard a card: Target player gains 3 life.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Hope Charm

Choose one —
• Target creature gains first strike until end of turn.
• Target player gains 2 life.
• Destroy target Aura.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Orzhov Guildmage

{2}{W}: Target player gains 1 life.
{2}{B}: Each player loses 1 life.

Treasury Thrull

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever this creature attacks, you may return target artifact, creature, or enchantment card from your graveyard to your hand.

Aurora of Emrakul

Flying, deathtouch
Whenever this creature attacks, each opponent loses 3 life.

Cryptolith Fragment

This artifact enters tapped.
{T}: Add one mana of any color. Each player loses 1 life.
At the beginning of your upkeep, if each player has 10 or less life, transform this artifact.

Cryptolith Fragment // Aurora of Emrakul

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Armistice

{3}{W}{W}: You draw a card and target opponent gains 3 life.

Silverquill Command

Choose two —
• Target creature gets +3/+3 and gains flying until end of turn.
• Return target creature card with mana value 2 or less from your graveyard to the battlefield.
• Target player draws a card and loses 1 life.
• Target opponent sacrifices a creature of their choice.

Ayara's Oathsworn

Menace
Whenever this creature deals combat damage to a player, if it has fewer than four +1/+1 counters on it, put a +1/+1 counter on it. Then if it has exactly four +1/+1 counters on it, search your library for a card, put it into your hand, then shuffle.

Insatiable Avarice

Spree (Choose one or more additional costs.)
+ {2} — Search your library for a card, then shuffle and put that card on top.
+ {B}{B} — Target player draws three cards and loses 3 life.

Moon-Blessed Cleric

Divine Intervention — When this creature enters, you may search your library for an enchantment card, reveal it, then shuffle and put that card on top.

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Touch of the Eternal

At the beginning of your upkeep, count the number of permanents you control. Your life total becomes that number.

Rest for the Weary

Target player gains 4 life.
Landfall — If you had a land enter the battlefield under your control this turn, that player gains 8 life instead.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Beseech the Queen

({2/B} can be paid with any two mana or with {B}. This card's mana value is 6.)
Search your library for a card with mana value less than or equal to the number of lands you control, reveal it, put it into your hand, then shuffle.

Soothing Balm

Agent of Masks

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Healing Hands

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Alabaster Potion

Choose one —
• Target player gains X life.
• Prevent the next X damage that would be dealt to any target this turn.

Sign in Blood

Target player draws two cards and loses 2 life.

Pontiff of Blight

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Other creatures you control have extort. (If a creature has multiple instances of extort, each triggers separately.)

Baneful Omen

At the beginning of your end step, you may reveal the top card of your library. If you do, each opponent loses life equal to that card's mana value.

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

God-Pharaoh's Statue

Spells your opponents cast cost {2} more to cast.
At the beginning of your end step, each opponent loses 1 life.

Wretched Confluence

Choose three. You may choose the same mode more than once.
• Target player draws a card and loses 1 life.
• Target creature gets -2/-2 until end of turn.
• Return target creature card from your graveyard to your hand.

Chancellor of the Dross

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent loses 3 life, then you gain life equal to the life lost this way.
Flying, lifelink

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.