High Synergy Cards

Tasha's Hideous Laughter

Each opponent exiles cards from the top of their library until that player has exiled cards with total mana value 20 or greater.

Top Cards

Fleet Swallower

Whenever this creature attacks, target player mills half their library, rounded up.

Fireshrieker

Equipped creature has double strike. (It deals both first-strike and regular combat damage.)
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Jace's Phantasm

Flying
This creature gets +4/+4 as long as an opponent has ten or more cards in their graveyard.

Fractured Sanity

Each opponent mills fourteen cards.
Cycling {1}{U} ({1}{U}, Discard this card: Draw a card.)
When you cycle this card, each opponent mills four cards.

Memory Erosion

Whenever an opponent casts a spell, that player mills two cards.

Fraying Sanity

Enchant player
At the beginning of each end step, enchanted player mills X cards, where X is the number of cards put into their graveyard from anywhere this turn.

Terisian Mindbreaker

Whenever this creature attacks, defending player mills half their library, rounded up.
Unearth {1}{U}{U}{U} ({1}{U}{U}{U}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Overture

Target opponent mills half their library, rounded down. (Then exile this card. You may play the land later from exile.)

Jidoor, Aristocratic Capital

Jidoor, Aristocratic Capital // Overture

Sapphire Medallion

Blue spells you cast cost {1} less to cast.

Ruin Crab

Landfall — Whenever a land you control enters, each opponent mills three cards. (To mill a card, a player puts the top card of their library into their graveyard.)

Bonehoard

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +X/+X, where X is the number of creature cards in all graveyards.
Equip {2}

Maddening Cacophony

Kicker {3}{U}
Each opponent mills eight cards. If this spell was kicked, instead each opponent mills half their library, rounded up.

Psychic Corrosion

Whenever you draw a card, each opponent mills two cards.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

The Mindskinner

The Mindskinner can't be blocked.
If a source you control would deal damage to an opponent, prevent that damage and each opponent mills that many cards.

Bruvac the Grandiloquent

If an opponent would mill one or more cards, they mill twice that many cards instead. (To mill a card, a player puts the top card of their library into their graveyard.)

Zellix, Sanity Flayer

Hive Mind — Whenever a player mills one or more creature cards, you create a 1/1 black Horror creature token.
{1}, {T}: Target player mills three cards.
Choose a Background (You can have a Background as a second commander.)

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Undead Alchemist

If a Zombie you control would deal combat damage to a player, instead that player mills that many cards.
Whenever a creature card is put into an opponent's graveyard from their library, exile that card and create a 2/2 black Zombie creature token.

Island

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.