Wrath of God

Destroy all creatures. They can't be regenerated.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Fell the Mighty

Destroy all creatures with power greater than target creature's power.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Dire Tactics

Exile target creature. If you don't control a Human, you lose life equal to that creature's toughness.

Mortify

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Ruinous Ultimatum

Destroy all nonland permanents your opponents control.

Divine Reckoning

Each player chooses a creature they control. Destroy the rest.
Flashback {5}{W}{W} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Bedevil

Destroy target artifact, creature, or planeswalker.

Kindred Dominance

Choose a creature type. Destroy all creatures that aren't of the chosen type.

Settle the Wreckage

Exile all attacking creatures target player controls. That player may search their library for that many basic land cards, put those cards onto the battlefield tapped, then shuffle.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Hour of Reckoning

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy all nontoken creatures.

Vindicate

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.