Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Netherborn Phalanx

When Netherborn Phalanx enters, each opponent loses 1 life for each creature they control.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then then shuffle. Transmute only as a sorcery.)

Utter End

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Sign in Blood

Target player draws two cards and loses 2 life.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Snuff Out

If you control a Swamp, you may pay 4 life rather than pay this spell's mana cost.
Destroy target nonblack creature. It can't be regenerated.

Resolute Archangel

Flying
When Resolute Archangel enters, if your life total is less than your starting life total, it becomes equal to your starting life total.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Near-Death Experience

At the beginning of your upkeep, if you have exactly 1 life, you win the game.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Orzhov Signet

Hatred

As an additional cost to cast this spell, pay X life.
Target creature gets +X/+0 until end of turn.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Star Compass

Star Compass enters tapped.
{T}: Add one mana of any color that a basic land you control could produce.

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Knight of the White Orchid

First strike
When Knight of the White Orchid enters, if an opponent controls more lands than you, you may search your library for a Plains card, put it onto the battlefield, then shuffle.

Burnished Hart

{3}, Sacrifice this creature: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Sol Ring

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Despark

Exile target permanent with mana value 4 or greater.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Thrull Parasite

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
{T}, Pay 2 life: Remove a counter from target nonland permanent.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Tainted Field

{T}: Add {C}.
{T}: Add {W} or {B}. Activate only if you control a Swamp.

Temple of Silence

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {W} or {B}.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Scoured Barrens

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {W} or {B}.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Oketra's Last Mercy

Your life total becomes equal to your starting life total. Lands you control don't untap during your next untap step.

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia, Dark Angel to its owner's hand.

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Hex Parasite

{X}{B/P}: Remove up to X counters from target permanent. For each counter removed this way, Hex Parasite gets +1/+0 until end of turn. ({B/P} can be paid with either {B} or 2 life.)

Plains

Return to Dust

Exile target artifact or enchantment. If you cast this spell during your main phase, you may exile up to one other target artifact or enchantment.

Exquisite Archangel

Flying
If you would lose the game, instead exile Exquisite Archangel and your life total becomes equal to your starting life total.

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Eternity Vessel

Eternity Vessel enters with X charge counters on it, where X is your life total.
Landfall — Whenever a land you control enters, you may have your life total become the number of charge counters on Eternity Vessel.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Mirror Universe

{T}, Sacrifice Mirror Universe: Exchange life totals with target opponent. Activate only during your upkeep.

Arcane Signet

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Orzhov Guildgate

This land enters tapped.
{T}: Add {W} or {B}.

Swamp

Reliquary Tower

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Necrologia

Cast this spell only during your end step.
As an additional cost to cast this spell, pay X life.
Draw X cards.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)