Sign in Blood

Target player draws two cards and loses 2 life.

Jhoira's Familiar

Flying
Historic spells you cast cost {1} less to cast. (Artifacts, legendaries, and Sagas are historic.)

Spider-Slayer, Hatred Honed

Whenever Spider-Slayer deals damage to a Spider, destroy that creature.
{6}, Exile this card from your graveyard: Create two tapped 1/1 colorless Robot artifact creature tokens with flying.

Laboratory Maniac

If you would draw a card while your library has no cards in it, you win the game instead.

Gilded Lotus

Prowler, Clawed Thief

Menace (This creature can't be blocked except by two or more creatures.)
Whenever another Villain you control enters, Prowler connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)

Vulture, Scheming Scavenger

Flying
Whenever Vulture attacks, other Villains you control gain flying until end of turn.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Dimir Signet

Dramatic Reversal

Untap all nonland permanents you control.

Grendel, Spawn of Knull

Flying (This creature can't be blocked except by creatures with flying or reach.)
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)

High Fae Trickster

Flash (You may cast this spell any time you could cast an instant.)
Flying
You may cast spells as though they had flash.

Changeling Outcast

Changeling (This card is every creature type.)
This creature can't block and can't be blocked.

Lady Octopus, Inspired Inventor

Whenever you draw your first or second card each turn, put an ingenuity counter on Lady Octopus.
{T}: You may cast an artifact spell from your hand with mana value less than or equal to the number of ingenuity counters on Lady Octopus without paying its mana cost.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. This artifact deals 1 damage to you.

Thran Dynamo

Tombstone, Career Criminal

When Tombstone enters, return target Villain card from your graveyard to your hand.
Villain spells you cast cost {1} less to cast.

The Soul Stone

Indestructible
{T}: Add {B}.
{6}{B}, {T}, Exile a creature you control: Harness The Soul Stone. (Once harnessed, its ∞ ability is active.)
∞ — At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.

Behold the Sinister Six!

Return up to six target creature cards with different names from your graveyard to the battlefield.

Beetle, Legacy Criminal

Flying
{1}{U}, Exile this card from your graveyard: Put a +1/+1 counter on target creature. It gains flying until end of turn. Activate only as a sorcery.

Dark Ritual

Swamp

Swarm, Being of Bees

Flash
Flying
Mayhem {B} (You may cast this card from your graveyard for {B} if you discarded it this turn. Timing rules still apply.)

The Spot's Portal

Put target creature on the bottom of its owner's library. You lose 2 life unless you control a Villain.

Reflections of Littjara

As this enchantment enters, choose a creature type.
Whenever you cast a spell of the chosen type, copy that spell. (A copy of a permanent spell becomes a token.)

Venomized Cat

Deathtouch
When this creature enters, mill two cards. (Put the top two cards of your library into your graveyard.)

Lethal Protection

Destroy target creature. Return up to one target creature card from your graveyard to your hand.

Black Cat, Cunning Thief

When Black Cat enters, look at the top nine cards of target opponent's library, exile two of them face down, then put the rest on the bottom of their library in a random order. You may play the exiled cards for as long as they remain exiled. Mana of any type can be spent to cast spells this way.

Lyla, Holographic Assistant

Whenever you draw a card, put a +1/+1 counter on target creature.

Spider-Sense

Web-slinging {U} (You may cast this spell for {U} if you also return a tapped creature you control to its owner's hand.)
Counter target instant spell, sorcery spell, or triggered ability.

Venom's Hunger

This spell costs {2} less to cast if you control a Villain.
Destroy target creature. You gain 2 life.

Living Brain, Mechanical Marvel

At the beginning of combat on your turn, target non-Equipment artifact you control becomes an artifact creature with base power and toughness 3/3 until end of turn. Untap it.

Venom, Eddie Brock

Menace (This creature can't be blocked except by two or more creatures.)
Whenever another creature dies, put a +1/+1 counter on Venom. If that creature was a Villain, draw a card.

Skirge Familiar

Ominous Seas

Whenever you draw a card, put a foreshadow counter on this enchantment.
Remove eight foreshadow counters from this enchantment: Create an 8/8 blue Kraken creature token.
Cycling {2} ({2}, Discard this card: Draw a card.)

Mysterio's Phantasm

Flying, vigilance
Whenever this creature attacks, mill a card. (Put the top card of your library into your graveyard.)

Mysterio, Master of Illusion

When Mysterio enters, create a 3/3 blue Illusion Villain creature token for each nontoken Villain you control. Exile those tokens when Mysterio leaves the battlefield.

Venom, Evil Unleashed

Deathtouch
{2}{B}, Exile this card from your graveyard: Put two +1/+1 counters on target creature. It gains deathtouch until end of turn. Activate only as a sorcery.

Sol Ring

Symbiote Spawn

When this creature dies, each opponent loses 2 life and you gain 2 life.

Frantic Search

Draw two cards, then discard two cards. Untap up to three lands.

Hedron Archive

{T}: Add {C}{C}.
{2}, {T}, Sacrifice this artifact: Draw two cards.

Doctor Octopus, Master Planner

Other Villains you control get +2/+2.
Your maximum hand size is eight.
At the beginning of your end step, if you have fewer than eight cards in hand, draw cards equal to the difference.

Rite of Replication

Kicker {5} (You may pay an additional {5} as you cast this spell.)
Create a token that's a copy of target creature. If this spell was kicked, create five of those tokens instead.

Morbius the Living Vampire

Flying, vigilance, lifelink
{U}{B}, Exile this card from your graveyard: Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order.

Mechanical Mobster

When this creature enters, exile up to one target card from a graveyard. Target creature you control connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on that creature.)

Palladium Myr

Mob Lookout

When this creature enters, target creature you control connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on that creature.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Flying Octobot

Flying
Whenever another Villain you control enters, put a +1/+1 counter on this creature. This ability triggers only once each turn.

Chameleon, Master of Disguise

You may have Chameleon enter as a copy of a creature you control, except his name is Chameleon, Master of Disguise.
Mayhem {2}{U} (You may cast this card from your graveyard for {2}{U} if you discarded it this turn. Timing rules still apply.)

Scry 1. (Look at the top card of your library. You may put that card on the bottom.)
Draw a card.

Doc Ock's Henchmen

Flash
Whenever this creature attacks, it connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)

Scorpion, Seething Striker

Deathtouch
At the beginning of your end step, if a creature died this turn, target creature you control connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on that creature.)

Common Crook

When this creature dies, create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Midnight Clock

{T}: Add {U}.
{2}{U}: Put an hour counter on this artifact.
At the beginning of each upkeep, put an hour counter on this artifact.
When the twelfth hour counter is put on this artifact, shuffle your hand and graveyard into your library, then draw seven cards. Exile this artifact.

Island

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice this artifact: Draw a card.

Mirror Box

The "legend rule" doesn't apply to permanents you control.
Each legendary creature you control gets +1/+1.
Each nontoken creature you control gets +1/+1 for each other creature you control with the same name as that creature.

Impostor Syndrome

Whenever a nontoken creature you control deals combat damage to a player, create a token that's a copy of it, except it isn't legendary.

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Herald's Horn

As this artifact enters, choose a creature type.
Creature spells you cast of the chosen type cost {1} less to cast.
At the beginning of your upkeep, look at the top card of your library. If it's a creature card of the chosen type, you may reveal it and put it into your hand.