Aunt May

Whenever another creature you control enters, you gain 1 life. If it's a Spider, put a +1/+1 counter on it.

Island

Silver Sable, Mercenary Leader

When Silver Sable enters, put a +1/+1 counter on another target creature.
Whenever Silver Sable attacks, target modified creature you control gains lifelink until end of turn. (Equipment, Auras you control, and counters are modifications.)

Biorganic Carapace

When this Equipment enters, attach it to target creature you control.
Equipped creature gets +2/+2 and has "Whenever this creature deals combat damage to a player, draw a card for each modified creature you control." (Equipment, Auras you control, and counters are modifications.)
Equip {2}

Vibrant Cityscape

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Selfless Police Captain

This creature enters with a +1/+1 counter on it.
When this creature leaves the battlefield, put its +1/+1 counters on target creature you control.

Hide on the Ceiling

Exile X target artifacts and/or creatures. Return the exiled cards to the battlefield under their owners' control at the beginning of the next end step.

Araña, Heart of the Spider

Whenever you attack, put a +1/+1 counter on target attacking creature.
Whenever a modified creature you control deals combat damage to a player, exile the top card of your library. You may play that card this turn. (Equipment, Auras you control, and counters are modifications.)

Origin of Spider-Man

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Create a 2/1 green Spider creature token with reach.
II — Put a +1/+1 counter on target creature you control. It becomes a legendary Spider Hero in addition to its other types.
III — Target creature you control gains double strike until end of turn.

Web-Shooters

Equipped creature gets +1/+1 and has reach and "Whenever this creature attacks, tap target creature an opponent controls."
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

University Campus

This land enters tapped.
{T}: Add {W} or {U}.
{4}, {T}: Surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Mountain

Shock

SP//dr, Piloted by Peni

Vigilance
When SP//dr enters, put a +1/+1 counter on target creature.
Whenever a modified creature you control deals combat damage to a player, draw a card. (Equipment, Auras you control, and counters are modifications.)

Daily Bugle Building

{T}: Add {C}.
{1}, {T}: Add one mana of any color.
Smear Campaign — {1}, {T}: Target legendary creature gains menace until end of turn. Activate only as a sorcery.

Costume Closet

This artifact enters with two +1/+1 counters on it.
{T}: Move a +1/+1 counter from this artifact onto target creature you control. Activate only as a sorcery.
Whenever a modified creature you control leaves the battlefield, put a +1/+1 counter on this artifact. (Equipment, Auras you control, and counters are modifications.)

Spider-Man, Web-Slinger

Web-slinging {W} (You may cast this spell for {W} if you also return a tapped creature you control to its owner's hand.)

Spider-Byte, Web Warden

When Spider-Byte enters, return up to one target nonland permanent to its owner's hand.

Ghost-Spider

Flying, vigilance, haste
Whenever you play a land from exile or cast a spell from exile, put a +1/+1 counter on Ghost-Spider.
Remove two counters from Ghost-Spider: Exile the top card of your library. You may play that card this turn.

Gwen Stacy

When Gwen Stacy enters, exile the top card of your library. You may play that card for as long as you control this creature.
{2}{U}{R}{W}: Transform Gwen Stacy. Activate only as a sorcery.

Gwen Stacy // Ghost-Spider

Heroes' Hangout

Choose one —
• Date Night — Exile the top two cards of your library. Choose one of them. Until the end of your next turn, you may play that card.
• Patrol Night — One or two target creatures each get +1/+0 and gain first strike until end of turn.

Spectacular Tactics

Choose one —
• Put a +1/+1 counter on target creature you control. It gains hexproof until end of turn.
• Destroy target creature with power 4 or greater.

Plains

Skyward Spider

Ward {2} (Whenever this creature becomes the target of a spell or ability an opponent controls, counter it unless that player pays {2}.)
This creature has flying as long as it's modified. (Equipment, Auras you control, and counters are modifications.)

Sun-Spider, Nimble Webber

During your turn, Sun-Spider has flying.
When Sun-Spider enters, search your library for an Aura or Equipment card, reveal it, put it into your hand, then shuffle.

Web Up

When this enchantment enters, exile target nonland permanent an opponent controls until this enchantment leaves the battlefield.