Vibrant Cityscape

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Lizard, Connors's Curse

Trample
Lizard Formula — When Lizard, Connors's Curse enters, up to one other target creature loses all abilities and becomes a green Lizard creature with base power and toughness 4/4.

Black Cat, Cunning Thief

When Black Cat enters, look at the top nine cards of target opponent's library, exile two of them face down, then put the rest on the bottom of their library in a random order. You may play the exiled cards for as long as they remain exiled. Mana of any type can be spent to cast spells this way.

Jackal, Genius Geneticist

Trample
Whenever you cast a creature spell with mana value equal to Jackal's power, copy that spell, except the copy isn't legendary. Then put a +1/+1 counter on Jackal. (The copy becomes a token.)

Oscorp Industries

This land enters tapped.
When this land enters from a graveyard, you lose 2 life.
{T}: Add {U}, {B}, or {R}.
Mayhem (You may play this card from your graveyard if you discarded it this turn. Timing rules still apply.)

Villainous Wrath

Target opponent loses life equal to the number of creatures they control. Then destroy all creatures.

Spinneret and Spiderling

Whenever you attack with two or more Spiders, put a +1/+1 counter on Spinneret and Spiderling.
Whenever Spinneret and Spiderling deals 4 or more damage, exile the top card of your library. Until the end of your next turn, you may play that card.

Spider-Woman, Stunning Savior

Flying
Venom Blast — Artifacts and creatures your opponents control enter tapped.

Strength of Will

Until end of turn, target creature you control gains indestructible and "Whenever this creature is dealt damage, put that many +1/+1 counters on it."

Aunt May

Whenever another creature you control enters, you gain 1 life. If it's a Spider, put a +1/+1 counter on it.

Rocket-Powered Goblin Glider

When this Equipment enters, if it was cast from your graveyard, attach it to target creature you control.
Equipped creature gets +2/+0 and has flying and haste.
Equip {2}
Mayhem {2}

Urban Retreat

This land enters tapped.
{T}: Add {G}, {W}, or {U}.
{2}, Return a tapped creature you control to its owner's hand: Put this card from your hand onto the battlefield. Activate only as a sorcery.

Biorganic Carapace

When this Equipment enters, attach it to target creature you control.
Equipped creature gets +2/+2 and has "Whenever this creature deals combat damage to a player, draw a card for each modified creature you control." (Equipment, Auras you control, and counters are modifications.)
Equip {2}

Behold the Sinister Six!

Return up to six target creature cards with different names from your graveyard to the battlefield.

Mary Jane Watson

Whenever a Spider you control enters, draw a card. This ability triggers only once each turn.

Scarlet Spider, Ben Reilly

Web-slinging {R}{G} (You may cast this spell for {R}{G} if you also return a tapped creature you control to its owner's hand.)
Trample
Sensational Save — If Scarlet Spider was cast using web-slinging, he enters with X +1/+1 counters on him, where X is the mana value of the returned creature.

Spider-Man Noir

Menace
Whenever a creature you control attacks alone, put a +1/+1 counter on it. Then surveil X, where X is the number of counters on it. (Look at the top X cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Arachne, Psionic Weaver

Web-slinging {W} (You may cast this spell for {W} if you also return a tapped creature you control to its owner's hand.)
As Arachne enters, look at an opponent's hand, then choose a card type other than creature.
Spells of the chosen type cost {1} more to cast.

Carnage, Crimson Chaos

Trample
When Carnage enters, return target creature card with mana value 3 or less from your graveyard to the battlefield. It gains "This creature attacks each combat if able" and "When this creature deals combat damage to a player, sacrifice it."
Mayhem {B}{R}

Araña, Heart of the Spider

Whenever you attack, put a +1/+1 counter on target attacking creature.
Whenever a modified creature you control deals combat damage to a player, exile the top card of your library. You may play that card this turn. (Equipment, Auras you control, and counters are modifications.)

Daily Bugle Building

{T}: Add {C}.
{1}, {T}: Add one mana of any color.
Smear Campaign — {1}, {T}: Target legendary creature gains menace until end of turn. Activate only as a sorcery.

Peter Parker's Camera

This artifact enters with three film counters on it.
{2}, {T}, Remove a film counter from this artifact: Copy target activated or triggered ability you control. You may choose new targets for the copy.

Agent Venom

Flash
Menace
Whenever another nontoken creature you control dies, you draw a card and lose 1 life.

Lady Octopus, Inspired Inventor

Whenever you draw your first or second card each turn, put an ingenuity counter on Lady Octopus.
{T}: You may cast an artifact spell from your hand with mana value less than or equal to the number of ingenuity counters on Lady Octopus without paying its mana cost.

Supportive Parents

Tap two untapped creatures you control: Add one mana of any color.

Spider-Slayer, Hatred Honed

Whenever Spider-Slayer deals damage to a Spider, destroy that creature.
{6}, Exile this card from your graveyard: Create two tapped 1/1 colorless Robot artifact creature tokens with flying.

SP//dr, Piloted by Peni

Vigilance
When SP//dr enters, put a +1/+1 counter on target creature.
Whenever a modified creature you control deals combat damage to a player, draw a card. (Equipment, Auras you control, and counters are modifications.)

Sandman, Shifting Scoundrel

Sandman's power and toughness are each equal to the number of lands you control.
Sandman can't be blocked by creatures with power 2 or less.
{3}{G}{G}: Return this card and target land card from your graveyard to the battlefield tapped.

Superior Spider-Man

Mind Swap — You may have Superior Spider-Man enter as a copy of any creature card in a graveyard, except his name is Superior Spider-Man and he's a 4/4 Spider Human Hero in addition to his other types. When you do, exile that card.

Doctor Octopus, Master Planner

Other Villains you control get +2/+2.
Your maximum hand size is eight.
At the beginning of your end step, if you have fewer than eight cards in hand, draw cards equal to the difference.

Ultimate Green Goblin

At the beginning of your upkeep, discard a card, then create a Treasure token.
Mayhem {2}{B/R} (You may cast this card from your graveyard for {2}{B/R} if you discarded it this turn. Timing rules still apply.)

Interdimensional Web Watch

When this artifact enters, exile the top two cards of your library. Until the end of your next turn, you may play those cards.
{T}: Add two mana in any combination of colors. Spend this mana only to cast spells from exile.

Comeuppance

Prevent all damage that would be dealt to you and planeswalkers you control this turn by sources you don't control. If damage from a creature source is prevented this way, Comeuppance deals that much damage to that creature. If damage from a noncreature source is prevented this way, Comeuppance deals that much damage to the source's controller.

Rent Is Due

At the beginning of your end step, you may tap two untapped creatures and/or Treasures you control. If you do, draw a card. Otherwise, sacrifice this enchantment.

Pictures of Spider-Man

When this artifact enters, look at the top five cards of your library. You may reveal up to two creature cards from among them and put them into your hand. Put the rest on the bottom of your library in a random order.
{1}, {T}, Sacrifice this artifact: Create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Shadow of the Goblin

Unreliable Visions — At the beginning of your first main phase, discard a card. If you do, draw a card.
Undying Vengeance — Whenever you play a land or cast a spell from anywhere other than your hand, this enchantment deals 1 damage to each opponent.

Spider-Punk

Riot (This creature enters with your choice of a +1/+1 counter or haste.)
Other Spiders you control have riot.
Spells and abilities can't be countered.
Damage can't be prevented.

Kraven's Last Hunt

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Mill five cards. When you do, this Saga deals damage equal to the greatest power among creature cards in your graveyard to target creature.
II — Target creature you control gets +2/+2 until end of turn.
III — Return target creature card from your graveyard to your hand.

J. Jonah Jameson

When J. Jonah Jameson enters, suspect up to one target creature. (A suspected creature has menace and can't block.)
Whenever a creature you control with menace attacks, create a Treasure token.

The Clone Saga

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Surveil 3.
II — When you next cast a creature spell this turn, copy it, except the copy isn't legendary.
III — Choose a card name. Whenever a creature with the chosen name deals combat damage to a player this turn, draw a card.

Ultimate Spider-Man

First strike, haste
Camouflage — {2}: Put a +1/+1 counter on Ultimate Spider-Man. He gains hexproof and becomes colorless until end of turn.
Whenever you attack, double the number of each kind of counter on each Spider and legendary creature you control.

Miles Morales

When Miles Morales enters, put a +1/+1 counter on each of up to two target creatures.
{3}{R}{G}{W}: Transform Miles Morales. Activate only as a sorcery.

Miles Morales // Ultimate Spider-Man

Iron Spider, Stark Upgrade

Vigilance
{T}: Put a +1/+1 counter on each artifact creature and/or Vehicle you control.
{2}, Remove two +1/+1 counters from among artifacts you control: Draw a card.

Silk, Web Weaver

Web-slinging {1}{G}{W} (You may cast this spell for {1}{G}{W} if you also return a tapped creature you control to its owner's hand.)
Whenever you cast a creature spell, create a 1/1 green and white Human Citizen creature token.
{3}{G}{W}: Creatures you control get +2/+2 and gain vigilance until end of turn.

Spider-Sense

Web-slinging {U} (You may cast this spell for {U} if you also return a tapped creature you control to its owner's hand.)
Counter target instant spell, sorcery spell, or triggered ability.

Spider-Verse

The "legend rule" doesn't apply to Spiders you control.
Whenever you cast a spell from anywhere other than your hand, you may copy it. If you do, you may choose new targets for the copy. If the copy is a permanent spell, it gains haste. Do this only once each turn.

Mysterio, Master of Illusion

When Mysterio enters, create a 3/3 blue Illusion Villain creature token for each nontoken Villain you control. Exile those tokens when Mysterio leaves the battlefield.