Feebleness

Flash
Enchant creature
Enchanted creature gets -2/-1.

Triumph of Cruelty

At the beginning of your upkeep, target opponent discards a card if you control the creature with the greatest power or tied for the greatest power.

Dead Weight

Enchant creature
Enchanted creature gets -2/-2.

Shadows of the Past

Whenever a creature dies, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{4}{B}: Each opponent loses 2 life and you gain 2 life. Activate only if there are four or more creature cards in your graveyard.

Mark of the Vampire

Enchant creature
Enchanted creature gets +2/+2 and has lifelink.

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Rune of Mortality

Enchant permanent
When Rune of Mortality enters, draw a card.
As long as enchanted permanent is a creature, it has deathtouch.
As long as enchanted permanent is an Equipment, it has "Equipped creature has deathtouch."

Vile Requiem

At the beginning of your upkeep, you may put a verse counter on Vile Requiem.
{1}{B}, Sacrifice Vile Requiem: Destroy up to X target nonblack creatures, where X is the number of verse counters on Vile Requiem. They can't be regenerated.

Debilitating Injury

Torment of Scarabs

Enchant player
At the beginning of enchanted player's upkeep, that player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.

Parasitic Implant

Enchant creature
At the beginning of your upkeep, enchanted creature's controller sacrifices it and you create a 1/1 colorless Phyrexian Myr artifact creature token.

Retreat to Hagra

Landfall — Whenever a land you control enters, choose one —
• Target creature gets +1/+0 and gains deathtouch until end of turn.
• Each opponent loses 1 life and you gain 1 life.

Raiders' Spoils

Creatures you control get +1/+0.
Whenever a Warrior you control deals combat damage to a player, you may pay 1 life. If you do, draw a card.

Hissing Miasma

Whenever a creature attacks you, its controller loses 1 life.

Precipitous Drop

Enchant creature
When Precipitous Drop enters, venture into the dungeon. (Enter the first room or advance to the next room.)
Enchanted creature gets -2/-2. It gets -5/-5 instead as long as you've completed a dungeon.

Oubliette

When Oubliette enters, target creature phases out until Oubliette leaves the battlefield. Tap that creature as it phases in this way. (Auras and Equipment phase out with it. While permanents are phased out, they're treated as though they don't exist.)

Crippling Blight

Enchant creature
Enchanted creature gets -1/-1 and can't block.

Relic Putrescence

Enchant artifact
Whenever enchanted artifact becomes tapped, its controller gets a poison counter.

Melancholy

Enchant creature
When Melancholy enters, tap enchanted creature.
Enchanted creature doesn't untap during its controller's untap step.
At the beginning of your upkeep, sacrifice Melancholy unless you pay {B}.

Eternal Thirst

Enchant creature
Enchanted creature has lifelink and "Whenever a creature an opponent controls dies, put a +1/+1 counter on this creature." (Damage dealt by a creature with lifelink also causes its controller to gain that much life.)

Hedonist's Trove

When Hedonist's Trove enters, exile target opponent's graveyard.
You may play lands from among cards exiled with Hedonist's Trove.
You may cast spells from among cards exiled with Hedonist's Trove. You can't cast more than one spell this way each turn.

Underhanded Designs

Whenever an artifact you control enters, you may pay {1}. If you do, each opponent loses 1 life and you gain 1 life.
{1}{B}, Sacrifice Underhanded Designs: Destroy target creature. Activate only if you control two or more artifacts.

Marchesa's Decree

When Marchesa's Decree enters, you become the monarch.
Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Cartouche of Ambition

Enchant creature you control
When Cartouche of Ambition enters, you may put a -1/-1 counter on target creature.
Enchanted creature gets +1/+1 and has lifelink.

Predator's Gambit

Enchant creature
Enchanted creature gets +2/+1.
Enchanted creature has intimidate as long as its controller controls no other creatures. (It can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Greed

Kaya's Ghostform

Enchant creature or planeswalker you control
When enchanted permanent dies or is put into exile, return that card to the battlefield under your control.

Sadistic Obsession

Enchant creature
Enchanted creature has "{B}, {T}: Put a -1/-1 counter on target creature."

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice Gonti's Machinations: Each opponent loses 3 life. You gain life equal to the life lost this way.

Creeping Dread

At the beginning of your upkeep, each player discards a card. Each opponent who discarded a card that shares a card type with the card you discarded loses 3 life. (Players reveal the discarded cards simultaneously.)

Death's Approach

Enchant creature
Enchanted creature gets -X/-X, where X is the number of creature cards in its controller's graveyard.

Trial of Ambition

When Trial of Ambition enters, target opponent sacrifices a creature of their choice.
When a Cartouche you control enters, return Trial of Ambition to its owner's hand.

Elspeth's Nightmare

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Destroy target creature an opponent controls with power 2 or less.
II — Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.
III — Exile target opponent's graveyard.

Aspect of Gorgon

Enchant creature
Enchanted creature gets +1/+3 and has deathtouch. (Any amount of damage it deals to a creature is enough to destroy it.)

Dead Man's Chest

Enchant creature an opponent controls
When enchanted creature dies, exile cards equal to its power from the top of its owner's library. You may cast spells from among those cards for as long as they remain exiled, and mana of any type can be spent to cast them.

Spiteful Shadows

Enchant creature
Whenever enchanted creature is dealt damage, it deals that much damage to its controller.

Gruesome Deformity

Enchant creature
Enchanted creature has intimidate. (It can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Seal of Doom

Sacrifice Seal of Doom: Destroy target nonblack creature. It can't be regenerated.

Honden of Night's Reach

At the beginning of your upkeep, target opponent discards a card for each Shrine you control.

World-Weary

Enchant creature
Enchanted creature gets -4/-4.
Basic landcycling {1}{B} ({1}{B}, Discard this card: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.)

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Revel in Riches

Whenever a creature an opponent controls dies, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
At the beginning of your upkeep, if you control ten or more Treasures, you win the game.

Quag Sickness

Enchant creature
Enchanted creature gets -1/-1 for each Swamp you control.

Deviant Glee

Enchant creature
Enchanted creature gets +2/+1 and has "{R}: This creature gains trample until end of turn."

Ill-Gotten Inheritance

At the beginning of your upkeep, Ill-Gotten Inheritance deals 1 damage to each opponent and you gain 1 life.
{5}{B}, Sacrifice Ill-Gotten Inheritance: It deals 4 damage to target opponent and you gain 4 life.

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your first main phase, add {B} for each charge counter on Black Market.

Deadly Wanderings

As long as you control exactly one creature, that creature gets +2/+0 and has deathtouch and lifelink.

Ancestral Vengeance

Enchant creature
When Ancestral Vengeance enters, put a +1/+1 counter on target creature you control.
Enchanted creature gets -1/-1.

Viper's Kiss

Enchant creature
Enchanted creature gets -1/-1, and its activated abilities can't be activated.

Sinister Concoction

{B}, Pay 1 life, Mill a card, Discard a card, Sacrifice Sinister Concoction: Destroy target creature.

Torture

Enchant creature
{1}{B}: Put a -1/-1 counter on enchanted creature.

Mire Blight

Enchant creature
When enchanted creature is dealt damage, destroy it.

Sanctum of Stone Fangs

At the beginning of your first main phase, each opponent loses X life and you gain X life, where X is the number of Shrines you control.

Deadly Designs

{2}: Put a plot counter on Deadly Designs. Any player may activate this ability.
When there are five or more plot counters on Deadly Designs, sacrifice it. If you do, destroy up to two target creatures.

Withercrown

Enchant creature
Enchanted creature has base power 0 and has "At the beginning of your upkeep, you lose 1 life unless you sacrifice this creature."

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Helm of the Ghastlord

Enchant creature
As long as enchanted creature is blue, it gets +1/+1 and has "Whenever this creature deals damage to an opponent, draw a card."
As long as enchanted creature is black, it gets +1/+1 and has "Whenever this creature deals damage to an opponent, that player discards a card."

Soul Stair Expedition

Landfall — Whenever a land you control enters, you may put a quest counter on Soul Stair Expedition.
Remove three quest counters from Soul Stair Expedition and sacrifice it: Return up to two target creature cards from your graveyard to your hand.

Night Dealings

Whenever a source you control deals damage to another player, put that many theft counters on Night Dealings.
{2}{B}{B}, Remove X theft counters from Night Dealings: Search your library for a nonland card with mana value X, reveal it, put it into your hand, then shuffle.

Oblivion Crown

Flash (You may cast this spell any time you could cast an instant.)
Enchant creature
Enchanted creature has "Discard a card: This creature gets +1/+1 until end of turn."

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Fear

Enchant creature (Target a creature as you cast this. This card enters attached to that creature.)
Enchanted creature has fear. (It can't be blocked except by artifact creatures and/or black creatures.)

Blood Reckoning

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Scourgemark

Enchant creature
When Scourgemark enters, draw a card.
Enchanted creature gets +1/+0.

Snake Cult Initiation

Enchant creature
Enchanted creature has poisonous 3. (Whenever it deals combat damage to a player, that player gets three poison counters. A player with ten or more poison counters loses the game.)

Behind the Scenes

Creatures you control have skulk. (They can't be blocked by creatures with greater power.)
{4}{W}: Creatures you control get +1/+1 until end of turn.

Grave Peril

When a nonblack creature enters, sacrifice Grave Peril. If you do, destroy that creature.

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Relic Bane

Enchant artifact
Enchanted artifact has "At the beginning of your upkeep, you lose 2 life."

Vampiric Link

Enchant creature
Whenever enchanted creature deals damage, you gain that much life.

Vessel of Malignity

{1}{B}, Sacrifice Vessel of Malignity: Target opponent exiles two cards from their hand. Activate only as a sorcery.

Sultai Runemark

Enchant creature
Enchanted creature gets +2/+2.
Enchanted creature has deathtouch as long as you control a green or blue permanent. (Any amount of damage it deals to a creature is enough to destroy it.)

Homicidal Seclusion

As long as you control exactly one creature, that creature gets +3/+1 and has lifelink.