Urianger Augurelt

Whenever you play a land from exile or cast a spell from exile, you gain 2 life.
Draw Arcanum — {T}: Look at the top card of your library. You may exile it face down.
Play Arcanum — {T}: Until end of turn, you may play cards exiled with Urianger Augurelt. Spells you cast this way cost {2} less to cast.

Tavern Brawler

Commander creatures you own have "At the beginning of your upkeep, exile the top card of your library. This creature gets +X/+0 until end of turn, where X is that card's mana value. You may play that card this turn."

Craig Boone, Novac Guard

Reach, lifelink
One for My Baby — Whenever you attack with two or more creatures, put two quest counters on Craig Boone. When you do, Craig Boone deals damage equal to the number of quest counters on it to up to one target creature unless that creature's controller has Craig Boone deal that much damage to them.

Eruth, Tormented Prophet

If you would draw a card, exile the top two cards of your library instead. You may play those cards this turn.

Monk Class

(Gain the next level as a sorcery to add its ability.)
The second spell you cast each turn costs {1} less to cast.
{W}{U}: Level 2
When this Class becomes level 2, return up to one target nonland permanent to its owner's hand.
{1}{W}{U}: Level 3
At the beginning of your upkeep, exile the top card of your library. For as long as it remains exiled, it has "You may cast this card from exile as long as you've cast another spell this turn."

Cait Sith, Fortune Teller

Lucky Slots — At the beginning of combat on your turn, scry 1, then exile the top card of your library. You may play that card this turn. When you exile a card this way, target creature you control gets +X/+0 until end of turn, where X is that card's mana value.

Have

Interdimensional Web Watch

When this artifact enters, exile the top two cards of your library. Until the end of your next turn, you may play those cards.
{T}: Add two mana in any combination of colors. Spend this mana only to cast spells from exile.

Silver Sable, Mercenary Leader

When Silver Sable enters, put a +1/+1 counter on another target creature.
Whenever Silver Sable attacks, target modified creature you control gains lifelink until end of turn. (Equipment, Auras you control, and counters are modifications.)

Spider-Man No More

Enchant creature
Enchanted creature is a Citizen with base power and toughness 1/1. It has defender and loses all other abilities. (It also loses all other creature types.)

Heroes' Hangout

Choose one —
• Date Night — Exile the top two cards of your library. Choose one of them. Until the end of your next turn, you may play that card.
• Patrol Night — One or two target creatures each get +1/+0 and gain first strike until end of turn.

Vega, the Watcher

Flying
Whenever you cast a spell from anywhere other than your hand, draw a card.

Professional Face-Breaker

Menace
Whenever one or more creatures you control deal combat damage to a player, create a Treasure token.
Sacrifice a Treasure: Exile the top card of your library. You may play that card this turn.

Commander Liara Portyr

Whenever you attack, spells you cast from exile this turn cost {X} less to cast, where X is the number of players being attacked. Exile the top X cards of your library. Until end of turn, you may cast spells from among those exiled cards.

Self-Destruct

Target creature you control deals X damage to any other target and X damage to itself, where X is its power.

War Squeak

Enchant creature
When this Aura enters, target creature an opponent controls can't block this turn.
Enchanted creature gets +1/+1 and has haste.

Grab the Reins

Choose one —
• Until end of turn, you gain control of target creature and it gains haste.
• Sacrifice a creature. Grab the Reins deals damage equal to that creature's power to any target.
Entwine {2}{R} (Choose both if you pay the entwine cost.)

Aunt May

Whenever another creature you control enters, you gain 1 life. If it's a Spider, put a +1/+1 counter on it.

Spider-Verse

The "legend rule" doesn't apply to Spiders you control.
Whenever you cast a spell from anywhere other than your hand, you may copy it. If you do, you may choose new targets for the copy. If the copy is a permanent spell, it gains haste. Do this only once each turn.

Overseer of Vault 76

First Contact — Whenever Overseer of Vault 76 or another creature you control with power 3 or less enters, put a quest counter on Overseer of Vault 76.
At the beginning of combat on your turn, you may remove three quest counters from among permanents you control. When you do, put a +1/+1 counter on each creature you control and they gain vigilance until end of turn.

Ghost-Spider

Flying, vigilance, haste
Whenever you play a land from exile or cast a spell from exile, put a +1/+1 counter on Ghost-Spider.
Remove two counters from Ghost-Spider: Exile the top card of your library. You may play that card this turn.

Gwen Stacy

When Gwen Stacy enters, exile the top card of your library. You may play that card for as long as you control this creature.
{2}{U}{R}{W}: Transform Gwen Stacy. Activate only as a sorcery.

Gwen Stacy // Ghost-Spider

Skyward Spider

Ward {2} (Whenever this creature becomes the target of a spell or ability an opponent controls, counter it unless that player pays {2}.)
This creature has flying as long as it's modified. (Equipment, Auras you control, and counters are modifications.)

Showdown of the Skalds

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Exile the top four cards of your library. Until the end of your next turn, you may play those cards.
II, III — Whenever you cast a spell this turn, put a +1/+1 counter on target creature you control.

Spider-Punk

Riot (This creature enters with your choice of a +1/+1 counter or haste.)
Other Spiders you control have riot.
Spells and abilities can't be countered.
Damage can't be prevented.

Spinneret and Spiderling

Whenever you attack with two or more Spiders, put a +1/+1 counter on Spinneret and Spiderling.
Whenever Spinneret and Spiderling deals 4 or more damage, exile the top card of your library. Until the end of your next turn, you may play that card.

Laelia, the Blade Reforged

Haste
Whenever Laelia attacks, exile the top card of your library. You may play that card this turn.
Whenever one or more cards are put into exile from your library and/or your graveyard, put a +1/+1 counter on Laelia.

Duchess, Wayward Tavernkeep

Hunters for Hire — Whenever a creature you control deals combat damage to a player, put a quest counter on it.
{1}, Remove a quest counter from a permanent you control: Create a Junk token. (It's an artifact with "{T}, Sacrifice this token: Exile the top card of your library. You may play that card this turn. Activate only as a sorcery.")

Spider-Man 2099

From the Future — You can't cast Spider-Man 2099 during your first, second, or third turns of the game.
Double strike, vigilance
At the beginning of your end step, if you've played a land or cast a spell this turn from anywhere other than your hand, Spider-Man 2099 deals damage equal to his power to any target.

Spider-Man, Web-Slinger

Web-slinging {W} (You may cast this spell for {W} if you also return a tapped creature you control to its owner's hand.)

Moira Brown, Guide Author

When Moira Brown enters, create a colorless Equipment artifact token named Wasteland Survival Guide with "Equipped creature gets +1/+1 for each quest counter among permanents you control" and equip {1}.
Whenever you attack, put a quest counter on target nonland permanent you control.

Spider-UK

Web-slinging {2}{W} (You may cast this spell for {2}{W} if you also return a tapped creature you control to its owner's hand.)
At the beginning of your end step, if two or more creatures entered the battlefield under your control this turn, you draw a card and gain 2 life.

Superior Foes of Spider-Man

Trample
Whenever you cast a spell with mana value 4 or greater, you may exile the top card of your library. If you do, you may play that card until you exile another card with this creature.

Pyrrhic Blast

As an additional cost to cast this spell, sacrifice a creature.
Pyrrhic Blast deals damage equal to the sacrificed creature's power to any target. Draw a card.

Madame Web, Clairvoyant

You may look at the top card of your library any time.
You may cast Spider spells and noncreature spells from the top of your library.
Whenever you attack, you may mill a card. (You may put the top card of your library into your graveyard.)

Biorganic Carapace

When this Equipment enters, attach it to target creature you control.
Equipped creature gets +2/+2 and has "Whenever this creature deals combat damage to a player, draw a card for each modified creature you control." (Equipment, Auras you control, and counters are modifications.)
Equip {2}

Impostor Syndrome

Whenever a nontoken creature you control deals combat damage to a player, create a token that's a copy of it, except it isn't legendary.

Thud

As an additional cost to cast this spell, sacrifice a creature.
Thud deals damage equal to the sacrificed creature's power to any target.

SP//dr, Piloted by Peni

Vigilance
When SP//dr enters, put a +1/+1 counter on target creature.
Whenever a modified creature you control deals combat damage to a player, draw a card. (Equipment, Auras you control, and counters are modifications.)

The War Doctor

Whenever one or more other permanents phase out and whenever one or more other cards are put into exile from anywhere, put a time counter on The War Doctor.
Whenever The War Doctor attacks, it deals damage equal to the number of time counters on it to any target. If a creature dealt damage this way would die this turn, exile it instead.

Wraith, Vicious Vigilante

Double strike
Fear Gas — Wraith can't be blocked.

Brion Stoutarm

Lifelink
{R}, {T}, Sacrifice another creature: Brion Stoutarm deals damage equal to the sacrificed creature's power to target player or planeswalker.

Count on Luck

At the beginning of your upkeep, exile the top card of your library. You may play that card this turn.

Fling

As an additional cost to cast this spell, sacrifice a creature.
Fling deals damage equal to the sacrificed creature's power to any target.

Kami of Celebration

Whenever a modified creature you control attacks, exile the top card of your library. You may play that card this turn. (Equipment, Auras you control, and counters are modifications.)
Whenever you cast a spell from exile, put a +1/+1 counter on target creature you control.

Araña, Heart of the Spider

Whenever you attack, put a +1/+1 counter on target attacking creature.
Whenever a modified creature you control deals combat damage to a player, exile the top card of your library. You may play that card this turn. (Equipment, Auras you control, and counters are modifications.)

Sage of the Beyond

Flying
Spells you cast from anywhere other than your hand cost {2} less to cast.
Foretell {4}{U} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)