Leyline of Mutation

If this card is in your opening hand, you may begin the game with it on the battlefield.
You may pay {W}{U}{B}{R}{G} rather than pay the mana cost for spells you cast.

Indominus Rex, Alpha

As Indominus Rex enters, discard any number of creature cards. It enters with a flying counter on it if a card discarded this way has flying. The same is true for first strike, double strike, deathtouch, hexproof, haste, indestructible, lifelink, menace, reach, trample, and vigilance.
When Indominus Rex enters, draw a card for each counter on it.

The Wise Mothman

Flying
Whenever The Wise Mothman enters or attacks, each player gets a rad counter.
Whenever one or more nonland cards are milled, put a +1/+1 counter on each of up to X target creatures, where X is the number of nonland cards milled this way.

Jenova, Ancient Calamity

At the beginning of combat on your turn, put a number of +1/+1 counters equal to Jenova's power on up to one other target creature. That creature becomes a Mutant in addition to its other types.
Whenever a Mutant you control dies during your turn, you draw cards equal to its power.

Mutalith Vortex Beast

Trample
Warp Vortex — When this creature enters, flip a coin for each opponent you have. For each flip you win, draw a card. For each flip you lose, this creature deals 3 damage to that player.

Leonardo, the Balance

Whenever a token you control enters, you may put a +1/+1 counter on each creature you control. Do this only once each turn.
{W}{U}{B}{R}{G}: Creatures you control gain menace, trample, and lifelink until end of turn.
Partner—Character select (You can have two commanders if both have this ability.)

Vigean Graftmage

Graft 2 (This creature enters with two +1/+1 counters on it. Whenever another creature enters, you may move a +1/+1 counter from this creature onto it.)
{1}{U}: Untap target creature with a +1/+1 counter on it.

Hancock, Ghoulish Mayor

Each other creature you control that's a Zombie or Mutant gets +X/+X, where X is the number of counters on Hancock.
Undying (When this creature dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)

Necropanther

Mutate {2}{W/B}{W/B} (If you cast this spell for its mutate cost, put it over or under target non-Human creature you own. They mutate into the creature on top plus all abilities from under it.)
Whenever this creature mutates, return target creature card with mana value 3 or less from your graveyard to the battlefield.

Boneyard Lurker

Mutate {2}{B/G}{B/G} (If you cast this spell for its mutate cost, put it over or under target non-Human creature you own. They mutate into the creature on top plus all abilities from under it.)
Whenever this creature mutates, return target permanent card from your graveyard to your hand.

Raphael, Tag Team Tough

Menace (This creature can't be blocked except by two or more creatures.)
Whenever Raphael deals combat damage to a player for the first time each turn, untap all attacking creatures. After this combat phase, there is an additional combat phase.

Michelangelo, On the Scene

Trample (This creature can deal excess combat damage to the player it's attacking.)
Michelangelo enters with a +1/+1 counter on him for each land you control.
When Michelangelo dies, return this card to your hand.

Raphael, the Muscle

Double all damage that creatures you control with counters on them would deal.
When Raphael enters, create a Mutagen token.
Partner—Character select (You can have two commanders if both have this ability.)

Gemrazer

Mutate {1}{G}{G} (If you cast this spell for its mutate cost, put it over or under target non-Human creature you own. They mutate into the creature on top plus all abilities from under it.)
Reach, trample
Whenever this creature mutates, destroy target artifact or enchantment an opponent controls.

Cytoplast Root-Kin

Graft 4 (This creature enters with four +1/+1 counters on it. Whenever another creature enters, you may move a +1/+1 counter from this creature onto it.)
When this creature enters, put a +1/+1 counter on each other creature you control with a +1/+1 counter on it.
{2}: Move a +1/+1 counter from target creature you control onto this creature.

Repulsive Mutation

Put X +1/+1 counters on target creature you control. Then counter up to one target spell unless its controller pays mana equal to the greatest power among creatures you control.

Indoraptor, the Perfect Hybrid

Bloodthirst X (This creature enters with X +1/+1 counters on it, where X is the damage dealt to your opponents this turn.)
Menace
Enrage — Whenever Indoraptor is dealt damage, choose an opponent at random. Indoraptor deals damage equal to its power to that player unless they sacrifice a nontoken creature of their choice.

Heroes in a Half Shell

Vigilance, menace, trample, haste
Whenever one or more Mutants, Ninjas, and/or Turtles you control deal combat damage to a player, put a +1/+1 counter on each of those creatures and draw a card.

Lumbering Megasloth

This spell costs {1} less to cast for each counter among players and permanents.
Trample
This creature enters tapped.

Nethroi, Apex of Death

Mutate {4}{G/W}{B}{B} (If you cast this spell for its mutate cost, put it over or under target non-Human creature you own. They mutate into the creature on top plus all abilities from under it.)
Deathtouch, lifelink
Whenever this creature mutates, return any number of target creature cards with total power 10 or less from your graveyard to the battlefield.

Artifact Mutation

Destroy target artifact. It can't be regenerated. Create X 1/1 green Saproling creature tokens, where X is that artifact's mana value.

Master Biomancer

Each other creature you control enters with a number of additional +1/+1 counters on it equal to this creature's power and as a Mutant in addition to its other types.

Aether Mutation

Return target creature to its owner's hand. Create X 1/1 green Saproling creature tokens, where X is that creature's mana value.

Vault 87: Forced Evolution

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Gain control of target non-Mutant creature for as long as you control this Saga.
II — Put a +1/+1 counter on target creature you control. It becomes a Mutant in addition to its other types.
III — Draw cards equal to the greatest power among Mutants you control.

Alpha Deathclaw

Menace, trample
When this creature enters or becomes monstrous, destroy target permanent.
{5}{B}{G}: Monstrosity 4. (If this creature isn't monstrous, put four +1/+1 counters on it and it becomes monstrous.)

Illuna, Apex of Wishes

Mutate {3}{R/G}{U}{U} (If you cast this spell for its mutate cost, put it over or under target non-Human creature you own. They mutate into the creature on top plus all abilities from under it.)
Flying, trample
Whenever this creature mutates, exile cards from the top of your library until you exile a nonland permanent card. Put that card onto the battlefield or into your hand.

Chaos Mutation

Exile any number of target creatures controlled by different players. For each creature exiled this way, its controller reveals cards from the top of their library until they reveal a creature card, puts that card onto the battlefield, then puts the rest on the bottom of their library in a random order.

Evolution Witness

{1}{G}: Adapt 2. (If this creature has no +1/+1 counters on it, put two +1/+1 counters on it.)
Whenever one or more +1/+1 counters are put on this creature, return target permanent card from your graveyard to your hand.

Michelangelo, the Heart

Trample
Raid (the Fridge) — At the beginning of your second main phase, if you attacked this turn, put a +1/+1 counter on target creature and create a Food token.
Partner—Character select (You can have two commanders if both have this ability.)

Mutated Cultist

Devoid (This card has no color.)
When you cast this spell, remove all counters from up to one target permanent or opponent. The next spell you cast this turn costs {1} less to cast for each counter removed this way.
Deathtouch

Leonardo, Sewer Samurai

Sneak {2}{W}{W}
Double strike
During your turn, you may cast creature spells with power or toughness 1 or less from your graveyard. If you cast a spell this way, that creature enters with a finality counter on it. (If a creature with a finality counter on it would die, exile it instead.)

Migratory Greathorn

Mutate {2}{G} (If you cast this spell for its mutate cost, put it over or under target non-Human creature you own. They mutate into the creature on top plus all abilities from under it.)
Whenever this creature mutates, search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Donatello, the Brains

If one or more tokens would be created under your control, those tokens plus a Mutagen token are created instead.
Partner—Character select (You can have two commanders if both have this ability.)

Vexing Radgull

Flying
Whenever this creature deals combat damage to a player, that player gets two rad counters if they don't have any rad counters. Otherwise, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Agent Frank Horrigan

Trample
Agent Frank Horrigan has indestructible as long as it attacked this turn.
Whenever Agent Frank Horrigan enters or attacks, proliferate twice. (To proliferate, choose any number of permanents and/or players, then give each another counter of each kind already there.)

Experiment Kraj

Experiment Kraj has all activated abilities of each other creature with a +1/+1 counter on it.
{T}: Put a +1/+1 counter on target creature.

Splinter, the Mentor

Menace
Whenever Splinter or another nontoken creature you control leaves the battlefield, create a Mutagen token.
Partner—Character select (You can have two commanders if both have this ability.)

Death Mutation

Destroy target nonblack creature. It can't be regenerated. Create X 1/1 green Saproling creature tokens, where X is that creature's mana value.

Biomass Mutation

Creatures you control have base power and toughness X/X until end of turn.

Mutational Advantage

Permanents you control with counters on them gain hexproof and indestructible until end of turn. Prevent all damage that would be dealt to those permanents this turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Elvish Soultiller

When this creature dies, choose a creature type. Shuffle all creature cards of that type from your graveyard into your library.

Aura Mutation

Destroy target enchantment. Create X 1/1 green Saproling creature tokens, where X is that enchantment's mana value.

Roalesk, Apex Hybrid

Flying, trample
When Roalesk enters, put two +1/+1 counters on another target creature you control.
When Roalesk dies, proliferate, then proliferate again. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Young Deathclaws

Menace (This creature can't be blocked except by two or more creatures.)
Each creature card in your graveyard has scavenge. The scavenge cost is equal to its mana cost. (Exile a creature card from your graveyard and pay its mana cost: Put a number of +1/+1 counters equal to that card's power on target creature. Scavenge only as a sorcery.)

Merfolk Skydiver

Flying
When this creature enters, put a +1/+1 counter on target creature you control.
{3}{G}{U}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Marcus, Mutant Mayor

Vigilance, trample
Whenever a creature you control deals combat damage to a player, draw a card if that creature has a +1/+1 counter on it. If it doesn't, put a +1/+1 counter on it.

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

Plaxcaster Frogling

Graft 3 (This creature enters with three +1/+1 counters on it. Whenever another creature enters, you may move a +1/+1 counter from this creature onto it.)
{2}: Target creature with a +1/+1 counter on it gains shroud until end of turn. (It can't be the target of spells or abilities.)

Jason Bright, Glowing Prophet

Whenever a Zombie or Mutant you control dies, if its power was different from its base power, draw a card.
Come Fly With Me — {2}, Sacrifice a creature: Put a +1/+1 counter on target creature you control. It gains flying until end of turn.

The Master, Transcendent

When The Master enters, target player gets two rad counters.
{T}: Put target creature card in a graveyard that was milled this turn onto the battlefield under your control. It's a green Mutant with base power and toughness 3/3. (It loses its other colors and creature types.)

Aberrant

Ravenous (This creature enters with X +1/+1 counters on it. If X is 5 or more, draw a card when it enters.)
Trample
Heavy Power Hammer — Whenever this creature deals combat damage to a player, destroy target artifact or enchantment that player controls.

Wolverine, Best There Is

Unrivaled Lethality — Double all damage Wolverine would deal.
At the beginning of each end step, if Wolverine dealt damage to another creature this turn, put a +1/+1 counter on him.
{1}{G}: Regenerate Wolverine. (The next time he would be destroyed this turn, instead tap him, remove him from combat, and heal all damage on him.)