Spider-Slayer, Hatred Honed

Whenever Spider-Slayer deals damage to a Spider, destroy that creature.
{6}, Exile this card from your graveyard: Create two tapped 1/1 colorless Robot artifact creature tokens with flying.

Doc Ock, Sinister Scientist

As long as there are eight or more cards in your graveyard, Doc Ock has base power and toughness 8/8.
As long as you control another Villain, Doc Ock has hexproof. (He can't be the target of spells or abilities your opponents control.)

Sinister Hideout

This land enters tapped.
{T}: Add {U} or {B}.
{4}, {T}: Surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Venom, Evil Unleashed

Deathtouch
{2}{B}, Exile this card from your graveyard: Put two +1/+1 counters on target creature. It gains deathtouch until end of turn. Activate only as a sorcery.

Daily Bugle Building

{T}: Add {C}.
{1}, {T}: Add one mana of any color.
Smear Campaign — {1}, {T}: Target legendary creature gains menace until end of turn. Activate only as a sorcery.

Spider-Man No More

Enchant creature
Enchanted creature is a Citizen with base power and toughness 1/1. It has defender and loses all other abilities. (It also loses all other creature types.)

Have

Island

Risky Research

Surveil 2, then draw two cards. You lose 2 life. (To surveil 2, look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Swamp

Whoosh!

Kicker {1}{U} (You may pay an additional {1}{U} as you cast this spell.)
Return target nonland permanent to its owner's hand. If this spell was kicked, draw a card.

Venom's Hunger

This spell costs {2} less to cast if you control a Villain.
Destroy target creature. You gain 2 life.

Beetle, Legacy Criminal

Flying
{1}{U}, Exile this card from your graveyard: Put a +1/+1 counter on target creature. It gains flying until end of turn. Activate only as a sorcery.

Mysterio's Phantasm

Flying, vigilance
Whenever this creature attacks, mill a card. (Put the top card of your library into your graveyard.)

Unstable Experiment

Target player draws a card, then up to one target creature you control connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on that creature.)

Flying Octobot

Flying
Whenever another Villain you control enters, put a +1/+1 counter on this creature. This ability triggers only once each turn.

Morbius the Living Vampire

Flying, vigilance, lifelink
{U}{B}, Exile this card from your graveyard: Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order.

Scorpion's Sting

Target creature gets -3/-3 until end of turn.

Mob Lookout

When this creature enters, target creature you control connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on that creature.)

Venomized Cat

Deathtouch
When this creature enters, mill two cards. (Put the top two cards of your library into your graveyard.)