Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Hydroid Krasis

When you cast this spell, you gain half X life and draw half X cards. Round down each time.
Flying, trample
This creature enters with X +1/+1 counters on it.

Consuming Sepulcher

At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Tithing Blade

When this artifact enters, each opponent sacrifices a creature of their choice.
Craft with creature {4}{B} ({4}{B}, Exile this artifact, Exile a creature you control or a creature card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Tithing Blade // Consuming Sepulcher

Restart Sequence

Freerunning {1}{B} (You may cast this spell for its freerunning cost if you dealt combat damage to a player this turn with an Assassin or commander.)
Return target creature card from your graveyard to the battlefield.

Agadeem, the Undercrypt

As this land enters, you may pay 3 life. If you don't, it enters tapped.
{T}: Add {B}.

Agadeem's Awakening

Return from your graveyard to the battlefield any number of target creature cards that each have a different mana value X or less.

Agadeem's Awakening // Agadeem, the Undercrypt

Teval, Arbiter of Virtue

Flying, lifelink
Spells you cast have delve. (Each card you exile from your graveyard while casting those spells pays for {1}.)
Whenever you cast a spell, you lose life equal to its mana value.

Will of the Abzan

Choose one. If you control a commander as you cast this spell, you may choose both instead.
• Any number of target opponents each sacrifice a creature with the greatest power among creatures that player controls and lose 3 life.
• Return target creature card from your graveyard to the battlefield.

Deep Analysis

Target player draws two cards.
Flashback—{1}{U}, Pay 3 life. (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Underrealm Lich

If you would draw a card, instead look at the top three cards of your library, then put one into your hand and the rest into your graveyard.
Pay 4 life: This creature gains indestructible until end of turn. Tap it.

Phyrexian Delver

When this creature enters, return target creature card from your graveyard to the battlefield. You lose life equal to that card's mana value.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Hunter's Bow

When this Equipment enters, attach it to target creature you control. That creature deals damage equal to its power to up to one target creature you don't control.
Equipped creature has reach and ward {2}.
Equip {1}

Bloodthirsty Conqueror

Flying, deathtouch
Whenever an opponent loses life, you gain that much life. (Damage causes loss of life.)

Qarsi Revenant

Flying, deathtouch, lifelink
Renew — {2}{B}, Exile this card from your graveyard: Put a flying counter, a deathtouch counter, and a lifelink counter on target creature. Activate only as a sorcery.

Uro, Titan of Nature's Wrath

When Uro enters, sacrifice it unless it escaped.
Whenever Uro enters or attacks, you gain 3 life and draw a card, then you may put a land card from your hand onto the battlefield.
Escape—{G}{G}{U}{U}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Haywire Mite

When this creature dies, you gain 2 life.
{G}, Sacrifice this creature: Exile target noncreature artifact or noncreature enchantment.

Metamorphosis Fanatic

Lifelink
When this creature enters, return up to one target creature card from your graveyard to the battlefield with a lifelink counter on it.
Miracle {1}{B} (You may cast this card for its miracle cost when you draw it if it's the first card you drew this turn.)

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Tamiyo's Safekeeping

Target permanent you control gains hexproof and indestructible until end of turn. You gain 2 life. (A permanent with hexproof and indestructible can't be the target of spells or abilities your opponents control. Damage and effects that say "destroy" don't destroy it.)

Nullpriest of Oblivion

Kicker {3}{B} (You may pay an additional {3}{B} as you cast this spell.)
Lifelink
Menace (This creature can't be blocked except by two or more creatures.)
When this creature enters, if it was kicked, return target creature card from your graveyard to the battlefield.

Eldrazi Ravager

Annihilator 1 (Whenever this creature attacks, defending player sacrifices a permanent of their choice.)
Sacrifice two Eldrazi: Return this card from your graveyard to your hand.
Cycling {2} ({2}, Discard this card: Draw a card.)

Jarad, Golgari Lich Lord

Jarad gets +1/+1 for each creature card in your graveyard.
{1}{B}{G}, Sacrifice another creature: Each opponent loses life equal to the sacrificed creature's power.
Sacrifice a Swamp and a Forest: Return this card from your graveyard to your hand.

Whip of Erebos

Creatures you control have lifelink.
{2}{B}{B}, {T}: Return target creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step. If it would leave the battlefield, exile it instead of putting it anywhere else. Activate only as a sorcery.

Creeping Bloodsucker

At the beginning of your upkeep, this creature deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik.

Junji, the Midnight Sky

Flying, menace
When Junji dies, choose one —
• Each opponent discards two cards and loses 2 life.
• Put target non-Dragon creature card from a graveyard onto the battlefield under your control. You lose 2 life.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Locthwain Scorn

Target creature gets -3/-3 until end of turn. You gain 2 life.

Virtue of Persistence

At the beginning of your upkeep, put target creature card from a graveyard onto the battlefield under your control.

Virtue of Persistence // Locthwain Scorn

Nature's Claim

Destroy target artifact or enchantment. Its controller gains 4 life.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to that card's mana value.

Druid Class

(Gain the next level as a sorcery to add its ability.)
Landfall — Whenever a land you control enters, you gain 1 life.
{2}{G}: Level 2
You may play an additional land on each of your turns.
{4}{G}: Level 3
When this Class becomes level 3, target land you control becomes a creature with haste and "This creature's power and toughness are each equal to the number of lands you control." It's still a land.

Wurmcoil Engine

Deathtouch, lifelink
When this creature dies, create a 3/3 colorless Phyrexian Wurm artifact creature token with deathtouch and a 3/3 colorless Phyrexian Wurm artifact creature token with lifelink.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature of their choice and you return up to one target creature card from your graveyard to your hand.

The Cruelty of Gix

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.
II — Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.
III — Put target creature card from a graveyard onto the battlefield under your control.

Ripples of Undeath

At the beginning of your first main phase, mill three cards. Then you may pay {1} and 3 life. If you do, put a card from among those cards into your hand.

Diresight

Surveil 2, then draw two cards. You lose 2 life. (To surveil 2, look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Gravebreaker Lamia

Lifelink
When this creature enters, search your library for a card, put it into your graveyard, then shuffle.
Spells you cast from your graveyard cost {1} less to cast.

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.