Terminate

Destroy target creature. It can't be regenerated.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Shadowgrange Archfiend

When this creature enters, each opponent sacrifices a creature with the greatest power among creatures they control. You gain life equal to the greatest power among creatures sacrificed this way.
Madness—{2}{B}, Pay 8 life. (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Insidious Dreams

As an additional cost to cast this spell, discard X cards.
Search your library for X cards, then shuffle and put those cards on top in any order.

Horror of the Broken Lands

Whenever you cycle or discard another card, this creature gets +2/+1 until end of turn.
Cycling {B} ({B}, Discard this card: Draw a card.)

Demonic Collusion

Buyback—Discard two cards. (You may discard two cards in addition to any other costs as you cast this spell. If you do, put this card into your hand as it resolves.)
Search your library for a card, put that card into your hand, then shuffle.

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. This artifact deals 1 damage to you.

Monument to Endurance

Whenever you discard a card, choose one that hasn't been chosen this turn —
• Draw a card.
• Create a Treasure token.
• Each opponent loses 3 life.

Bladewing, Deathless Tyrant

Flying, haste
Whenever Bladewing deals combat damage to a player or planeswalker, for each creature card in your graveyard, create a 2/2 black Zombie Knight creature token with menace.

Getting

The Deck of Many Things

{2}, {T}: Roll a d20 and subtract the number of cards in your hand. If the result is 0 or less, discard your hand.
1—9 | Return a card at random from your graveyard to your hand.
10—19 | Draw two cards.
20 | Put a creature card from any graveyard onto the battlefield under your control. When that creature dies, its owner loses the game.

Sol Ring

Nihilistic Glee

{2}{B}, Discard a card: Target opponent loses 1 life and you gain 1 life.
Hellbent — {1}, Pay 2 life: Draw a card. Activate only if you have no cards in hand.

Gibbering Descent

At the beginning of each player's upkeep, that player loses 1 life and discards a card.
Hellbent — Skip your upkeep step if you have no cards in hand.
Madness {2}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Malfegor

Flying
When Malfegor enters, discard your hand. Each opponent sacrifices a creature of their choice for each card discarded this way.

Bloodhall Priest

Whenever this creature enters or attacks, if you have no cards in hand, this creature deals 2 damage to any target.
Madness {1}{B}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Infernal Tutor

Reveal a card from your hand. Search your library for a card with the same name as that card, reveal it, put it into your hand, then shuffle.
Hellbent — If you have no cards in hand, instead search your library for a card, put it into your hand, then shuffle.

Rakdos Signet

Anje Falkenrath

Haste
{T}, Discard a card: Draw a card.
Whenever you discard a card, if it has madness, untap Anje Falkenrath.

Dark Withering

Destroy target nonblack creature.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Shadow of the Grave

Return to your hand all cards in your graveyard that you cycled or discarded this turn.