Faith's Shield

Target permanent you control gains protection from the color of your choice until end of turn.
Fateful hour — If you have 5 or less life, instead you and each permanent you control gain protection from the color of your choice until end of turn.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Immolating Souleater

{R/P}: Immolating Souleater gets +1/+0 until end of turn. ({R/P} can be paid with either {R} or 2 life.)

Death's Shadow

Death's Shadow gets -X/-X, where X is your life total.

Fling

As an additional cost to cast this spell, sacrifice a creature.
Fling deals damage equal to the sacrificed creature's power to any target.

Thraben Doomsayer

{T}: Create a 1/1 white Human creature token.
Fateful hour — As long as you have 5 or less life, other creatures you control get +2/+2.