Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on this enchantment.
At the beginning of each opponent's upkeep, if that player has no cards in hand and this enchantment has two or more quest counters on it, you may have that player lose 5 life.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Raven's Crime

Target player discards a card.
Retrace (You may cast this card from your graveyard by discarding a land card in addition to paying its other costs.)

Swamp

Underground Sea

Drowned Catacomb

This land enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Watery Grave

({T}: Add {U} or {B}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Hymn to Tourach

Target player discards two cards at random.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Lore Broker

{T}: Each player draws a card, then discards a card.

Sign in Blood

Target player draws two cards and loses 2 life.

Polluted Delta

{T}, Pay 1 life, Sacrifice this land: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Augur of Skulls

{1}{B}: Regenerate this creature.
Sacrifice this creature: Target player discards two cards. Activate only during your upkeep.