Shadowcloak Vampire

Pay 2 life: This creature gains flying until end of turn. (It can't be blocked except by creatures with flying or reach.)

Blood Price

Look at the top four cards of your library. Put two of them into your hand and the rest on the bottom of your library in any order. You lose 2 life.

Kuro, Pitlord

At the beginning of your upkeep, sacrifice Kuro unless you pay {B}{B}{B}{B}.
Pay 1 life: Target creature gets -1/-1 until end of turn.

Bellowing Saddlebrute

Raid — When this creature enters, you lose 4 life unless you attacked this turn.

Sign in Blood

Target player draws two cards and loses 2 life.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice this artifact: Draw a card.

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Dark Ritual

Strands of Night

{B}{B}, Pay 2 life, Sacrifice a Swamp: Return target creature card from your graveyard to the battlefield.

Necrologia

Cast this spell only during your end step.
As an additional cost to cast this spell, pay X life.
Draw X cards.

Songs of the Damned

Add {B} for each creature card in your graveyard.

Succumb to Temptation

Midnight Reaper

Whenever a nontoken creature you control dies, this creature deals 1 damage to you and you draw a card.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice this artifact: Draw a card.

Culling the Weak

As an additional cost to cast this spell, sacrifice a creature.
Add {B}{B}{B}{B}.

Dusk Legion Zealot

When this creature enters, you draw a card and you lose 1 life.

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Ancient Craving

You draw three cards and you lose 3 life.

Lurking Evil

Pay half your life, rounded up: This enchantment becomes a 4/4 Phyrexian Horror creature with flying.

Organ Harvest

Your team may sacrifice any number of creatures. For each creature sacrificed this way, you add {B}{B}.

Gallowbraid

Trample
Cumulative upkeep—Pay 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: This creature gets +1/+1 until end of turn.

Worn Powerstone

This artifact enters tapped.
{T}: Add {C}{C}.

Bane Alley Blackguard

Numai Outcast

Bushido 2 (Whenever this creature blocks or becomes blocked, it gets +2/+2 until end of turn.)
{B}, Pay 5 life: Regenerate this creature.

Hedron Archive

{T}: Add {C}{C}.
{2}, {T}, Sacrifice this artifact: Draw two cards.

Charcoal Diamond

This artifact enters tapped.
{T}: Add {B}.

Cabal Ritual

Add {B}{B}{B}.
Threshold — Add {B}{B}{B}{B}{B} instead if seven or more cards are in your graveyard.

Tavern Swindler

{T}, Pay 3 life: Flip a coin. If you win the flip, you gain 6 life.

Phyrexian Rager

Baleful Force

At the beginning of each upkeep, you draw a card and you lose 1 life.

Soul Channeling

Enchant creature
Pay 2 life: Regenerate enchanted creature.

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Funeral Rites

You draw two cards, lose 2 life, then mill two cards.

Phyrexian Lens

{T}, Pay 1 life: Add one mana of any color.

Bond of Agony

As an additional cost to cast this spell, pay X life.
Each other player loses X life.

Greed

Carrion Howler

Pay 1 life: This creature gets +2/-1 until end of turn.

Bile Urchin

Sacrifice this creature: Target player loses 1 life.

Grimclaw Bats

Flying
{B}, Pay 1 life: This creature gets +1/+1 until end of turn.

Banewasp Affliction

Enchant creature
When enchanted creature dies, that creature's controller loses life equal to its toughness.

Standing Stones

{1}, {T}, Pay 1 life: Add one mana of any color.

Minion of the Wastes

Trample
As this creature enters, pay any amount of life.
Minion of the Wastes's power and toughness are each equal to the life paid as it entered.

Vesper Ghoul

Damnable Pact

Target player draws X cards and loses X life.

Sinister Concoction

{B}, Pay 1 life, Mill a card, Discard a card, Sacrifice this enchantment: Destroy target creature.

Caustic Tar

Enchant land
Enchanted land has "{T}: Target player loses 3 life."

Live Fast

You draw two cards, lose 2 life, and get {E}{E} (two energy counters).

Audacious Thief

Whenever this creature attacks, you draw a card and you lose 1 life.

Swamp

Marshland Bloodcaster

Flying
{1}{B}, {T}: Rather than pay the mana cost of the next spell you cast this turn, you may pay life equal to that spell's mana value.

Hand of Vecna

At the beginning of combat on your turn, equipped creature or a creature you control named Vecna gets +X/+X until end of turn, where X is the number of cards in your hand.
Equip—Pay 1 life for each card in your hand.
Equip {2}

Book of Rass

Souldrinker

Pay 3 life: Put a +1/+1 counter on this creature.

Boon of Erebos

Target creature gets +2/+0 until end of turn. Regenerate it. You lose 2 life.

Blessing of Leeches

Flash
Enchant creature
At the beginning of your upkeep, you lose 1 life.
{0}: Regenerate enchanted creature.

Sisay's Ring

Bog Witch

Murderous Betrayal

{B}{B}, Pay half your life, rounded up: Destroy target nonblack creature. It can't be regenerated.