Nowhere to Run

Flash
When this enchantment enters, target creature an opponent controls gets -3/-3 until end of turn.
Creatures your opponents control can be the targets of spells and abilities as though they didn't have hexproof. Ward abilities of those creatures don't trigger.

Diresight

Surveil 2, then draw two cards. You lose 2 life. (To surveil 2, look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Spectral Searchlight

{T}: Choose a player. That player adds one mana of any color they choose.

Heartless Summoning

Creature spells you cast cost {2} less to cast.
Creatures you control get -1/-1.

Vindictive Vampire

Whenever another creature you control dies, this creature deals 1 damage to each opponent and you gain 1 life.

Teysa, Envoy of Ghosts

Vigilance, protection from creatures
Whenever a creature deals combat damage to you, destroy that creature. Create a 1/1 white and black Spirit creature token with flying.

Flesh Allergy

As an additional cost to cast this spell, sacrifice a creature.
Destroy target creature. Its controller loses life equal to the number of creatures that died this turn.

Ulamog, the Infinite Gyre

When you cast this spell, destroy target permanent.
Indestructible
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents of their choice.)
When Ulamog is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Undying Evil

Target creature gains undying until end of turn. (When it dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice this artifact: Draw a card.

Moonsilver Key

{1}, {T}, Sacrifice this artifact: Search your library for an artifact card with a mana ability or a basic land card, reveal it, put it into your hand, then shuffle.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Relic Vial

{2}, {T}, Sacrifice a creature: Draw a card.
As long as you control a Cleric, this artifact has "Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life."

Vampire Warlord

Sacrifice another creature: Regenerate this creature. (The next time this creature would be destroyed this turn, instead tap it, remove it from combat, and heal all damage on it.)

Nadier, Agent of the Duskenel

Whenever a token you control leaves the battlefield, put a +1/+1 counter on Nadier.
When Nadier leaves the battlefield, create a number of 1/1 green Elf Warrior creature tokens equal to its power.
Partner (You can have two commanders if both have partner.)

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent of their choice that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Priest of Gix

When this creature enters, add {B}{B}{B}.

Forever Young

Put any number of target creature cards from your graveyard on top of your library.
Draw a card.

Blood Bairn

Sacrifice another creature: This creature gets +2/+2 until end of turn.

Doom Blade

Pact Weapon

As long as this Equipment is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Champion's Helm

Equipped creature gets +2/+2.
As long as equipped creature is legendary, it has hexproof. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Manalith

Black Sun's Zenith

Put X -1/-1 counters on each creature. Shuffle Black Sun's Zenith into its owner's library.

Curse of the Cabal

Target player sacrifices half the permanents they control of their choice, rounded down.
Suspend 2—{2}{B}{B} (Rather than cast this card from your hand, you may pay {2}{B}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
At the beginning of each player's upkeep, if this card is suspended, that player may sacrifice a permanent of their choice. If the player does, put two time counters on this card.

Killing Wave

For each creature, its controller sacrifices it unless they pay X life.

Oubliette

When this enchantment enters, target creature phases out until this enchantment leaves the battlefield. Tap that creature as it phases in this way. (Auras and Equipment phase out with it. While permanents are phased out, they're treated as though they don't exist.)

Baleful Ammit

Lifelink
When this creature enters, put a -1/-1 counter on target creature you control.

Indulgent Tormentor

Flying
At the beginning of your upkeep, draw a card unless target opponent sacrifices a creature of their choice or pays 3 life.

Unhallowed Pact

Enchant creature
When enchanted creature dies, return that card to the battlefield under your control.

Pharika's Libation

Choose one —
• Target opponent sacrifices a creature of their choice.
• Target opponent sacrifices an enchantment of their choice.

Dead of Winter

All nonsnow creatures get -X/-X until end of turn, where X is the number of snow permanents you control.

Skyclave Shadowcat

{1}{B}, Sacrifice another creature: Put a +1/+1 counter on this creature.
Whenever a creature you control with a +1/+1 counter on it dies, draw a card.

Feral Ghoul

Menace
Whenever another creature you control dies, put a +1/+1 counter on this creature.
When this creature dies, each opponent gets a number of rad counters equal to its power.

Strionic Resonator

{2}, {T}: Copy target triggered ability you control. You may choose new targets for the copy. (A triggered ability uses the words "when," "whenever," or "at.")

Innocent Blood

Each player sacrifices a creature of their choice.

Nirkana Revenant

Whenever you tap a Swamp for mana, add an additional {B}.
{B}: This creature gets +1/+1 until end of turn.

Skulltap

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Animate Dead

Enchant creature card in a graveyard
When this Aura enters, if it's on the battlefield, it loses "enchant creature card in a graveyard" and gains "enchant creature put onto the battlefield with this Aura." Return enchanted creature card to the battlefield under your control and attach this Aura to it. When this Aura leaves the battlefield, that creature's controller sacrifices it.
Enchanted creature gets -1/-0.

Dross Hopper

Sacrifice a creature: This creature gains flying until end of turn.

Falkenrath Noble

Flying
Whenever this creature or another creature dies, target player loses 1 life and you gain 1 life.

Defiant Salvager

Sacrifice an artifact or creature: Put a +1/+1 counter on this creature. Activate only as a sorcery.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Kaervek, the Spiteful

Open the Graves

Whenever a nontoken creature you control dies, create a 2/2 black Zombie creature token.

Athreos, God of Passage

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
Whenever another creature you own dies, return it to your hand unless target opponent pays 3 life.

Bastion of Remembrance

When this enchantment enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Ob Nixilis, Unshackled

Flying, trample
Whenever an opponent searches their library, that player sacrifices a creature of their choice and loses 10 life.
Whenever another creature dies, put a +1/+1 counter on Ob Nixilis.

Witch's Cauldron

{1}{B}, {T}, Sacrifice a creature: You gain 1 life and draw a card.

Throne of Eldraine

As Throne of Eldraine enters, choose a color.
{T}: Add four mana of the chosen color. Spend this mana only to cast monocolored spells of that color.
{3}, {T}: Draw two cards. Spend only mana of the chosen color to activate this ability.

Nest of Scarabs

Whenever you put one or more -1/-1 counters on a creature, create that many 1/1 black Insect creature tokens.

Go for the Throat

Blood Artist

Whenever this creature or another creature dies, target player loses 1 life and you gain 1 life.

Marchesa, the Black Rose

Dethrone (Whenever this creature attacks the player with the most life or tied for most life, put a +1/+1 counter on it.)
Other creatures you control have dethrone.
Whenever a creature you control with a +1/+1 counter on it dies, return that card to the battlefield under your control at the beginning of the next end step.

Koskun Falls

At the beginning of your upkeep, sacrifice this enchantment unless you tap an untapped creature you control.
Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Supernatural Stamina

Until end of turn, target creature gets +2/+0 and gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Command Beacon

{T}: Add {C}.
{T}, Sacrifice this land: Put your commander into your hand from the command zone.

Cabal Conditioning

Any number of target players each discard a number of cards equal to the greatest mana value among permanents you control.

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Transmogrant's Crown

Equipped creature gets +2/+0.
Whenever equipped creature dies, draw a card.
Equip {2} or {B}

Fake Your Own Death

Until end of turn, target creature gets +2/+0 and gains "When this creature dies, return it to the battlefield tapped under its owner's control and you create a Treasure token." (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Flesh-Eater Imp

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Sacrifice a creature: This creature gets +1/+1 until end of turn.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Nevinyrral's Disk

This artifact enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Viscera Seer

Sacrifice a creature: Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Armor of Shadows

Until end of turn, target creature gets +1/+0 and gains indestructible. (Damage and effects that say "destroy" don't destroy it.)

Susurian Voidborn

Whenever this creature or another creature or artifact you control dies, target opponent loses 1 life and you gain 1 life.
Warp {B} (You may cast this card from your hand for its warp cost. Exile this creature at the beginning of the next end step, then you may cast it from exile on a later turn.)

Detection Tower

{T}: Add {C}.
{1}, {T}: Until end of turn, your opponents and creatures your opponents control with hexproof can be the targets of spells and abilities you control as though they didn't have hexproof.

Mastermind's Acquisition

Choose one —
• Search your library for a card, put it into your hand, then shuffle.
• Put a card you own from outside the game into your hand.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Skeletal Grimace

Enchant creature
Enchanted creature gets +1/+1 and has "{B}: Regenerate this creature."

Tragic Slip

Target creature gets -1/-1 until end of turn.
Morbid — That creature gets -13/-13 until end of turn instead if a creature died this turn.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Spark Reaper

{3}, Sacrifice a creature or planeswalker: You gain 1 life and draw a card.

Illuminor Szeras

Secrets of the Soul — {T}, Sacrifice another creature: Add an amount of {B} equal to the sacrificed creature's mana value.

Fallen Angel

Flying
Sacrifice a creature: This creature gets +2/+1 until end of turn.

Ancient Craving

You draw three cards and you lose 3 life.

The Core

(Transforms from Matzalantli.)
Fathomless descent — {T}: Add X mana of any one color, where X is the number of permanent cards in your graveyard.

Matzalantli, the Great Door

{T}: Draw a card, then discard a card.
{4}, {T}: Transform Matzalantli. Activate only if there are four or more permanent types among cards in your graveyard. (Artifact, battle, creature, enchantment, land, and planeswalker are permanent types.)

Matzalantli, the Great Door // The Core

Mutilate

All creatures get -1/-1 until end of turn for each Swamp you control.

Vindictive Lich

When this creature dies, choose one or more. Each mode must target a different player.
• Target opponent sacrifices a creature of their choice.
• Target opponent discards two cards.
• Target opponent loses 5 life.

Beseech the Queen

({2/B} can be paid with any two mana or with {B}. This card's mana value is 6.)
Search your library for a card with mana value less than or equal to the number of lands you control, reveal it, put it into your hand, then shuffle.

Infernal Tribute

{2}, Sacrifice a nontoken permanent: Draw a card.

Pact of the Serpent

Choose a creature type. Target player draws X cards and loses X life, where X is the number of creatures they control of the chosen type.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Mox Amber

{T}: Add one mana of any color among legendary creatures and planeswalkers you control.

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Kaya's Ghostform

Enchant creature or planeswalker you control
When enchanted permanent dies or is put into exile, return that card to the battlefield under your control.

Malakir Mire

Malakir Rebirth

Choose target creature. You lose 2 life. Until end of turn, that creature gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Malakir Rebirth // Malakir Mire

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik.

Grim Harvest

Return target creature card from your graveyard to your hand.
Recover {2}{B} (When a creature is put into your graveyard from the battlefield, you may pay {2}{B}. If you do, return this card from your graveyard to your hand. Otherwise, exile this card.)

Gate to Phyrexia

Sacrifice a creature: Destroy target artifact. Activate only during your upkeep and only once each turn.