Demogorgon's Clutches

Target opponent discards two cards, mills two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Megrim

Whenever an opponent discards a card, this enchantment deals 2 damage to that player.

Painful Lesson

Target player draws two cards and loses 2 life.

Liliana's Steward

{T}, Sacrifice this creature: Target opponent discards a card. Activate only as a sorcery.

Burglar Rat

When this creature enters, each opponent discards a card.

Drainpipe Vermin

When this creature dies, you may pay {B}. If you do, target player discards a card.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Bump in the Night

Target opponent loses 3 life.
Flashback {5}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Augur of Skulls

{1}{B}: Regenerate this creature.
Sacrifice this creature: Target player discards two cards. Activate only during your upkeep.