Titan Hunter

At the beginning of each player's end step, if no creatures died this turn, Titan Hunter deals 4 damage to that player.
{1}{B}, Sacrifice a creature: You gain 4 life.

Breath of Malfegor

Breath of Malfegor deals 5 damage to each opponent.

Banefire

Banefire deals X damage to any target.
If X is 5 or more, this spell can't be countered and the damage can't be prevented.

Sphinx-Bone Wand

Whenever you cast an instant or sorcery spell, you may put a charge counter on Sphinx-Bone Wand. If you do, Sphinx-Bone Wand deals damage equal to the number of charge counters on it to any target.

Rakdos's Return

Rakdos's Return deals X damage to target opponent or planeswalker. That player or that planeswalker's controller discards X cards.

Blightning

Blightning deals 3 damage to target player or planeswalker. That player or that planeswalker's controller discards two cards.

Worms of the Earth

Players can't play lands.
Lands can't enter the battlefield.
At the beginning of each upkeep, any player may sacrifice two lands of their choice or have Worms of the Earth deal 5 damage to that player. If a player does either, destroy Worms of the Earth.

Sulfuric Vortex

At the beginning of each player's upkeep, Sulfuric Vortex deals 2 damage to that player.
If a player would gain life, that player gains no life instead.