Soul Channeling

Enchant creature
Pay 2 life: Regenerate enchanted creature.

Greed

Defiler of Faith

Vigilance
As an additional cost to cast white permanent spells, you may pay 2 life. Those spells cost {W} less to cast if you paid life this way. This effect reduces only the amount of white mana you pay.
Whenever you cast a white permanent spell, create a 1/1 white Soldier creature token.

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Damnable Pact

Target player draws X cards and loses X life.

Phyrexian Lens

{T}, Pay 1 life: Add one mana of any color.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Final Payment

As an additional cost to cast this spell, pay 5 life or sacrifice a creature or enchantment.
Destroy target creature.

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Mischievous Poltergeist

Flying
Pay 1 life: Regenerate Mischievous Poltergeist.

Grollub

Whenever Grollub is dealt damage, each opponent gains that much life.

Snuff Out

If you control a Swamp, you may pay 4 life rather than pay this spell's mana cost.
Destroy target nonblack creature. It can't be regenerated.

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Wall of Shards

Defender, flying
Cumulative upkeep—An opponent gains 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Mirror Universe

{T}, Sacrifice Mirror Universe: Exchange life totals with target opponent. Activate only during your upkeep.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Pay No Heed

Prevent all damage a source of your choice would deal this turn.

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra, Halcyon Witness's power.

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia, Dark Angel to its owner's hand.

Devour Flesh

Target player sacrifices a creature of their choice, then gains life equal to that creature's toughness.

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)