Mirror Universe

{T}, Sacrifice this artifact: Exchange life totals with target opponent. Activate only during your upkeep.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, this creature gets +5/+5 and has flying.

Cruel Bargain

Draw four cards. You lose half your life, rounded up.

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Infernal Contract

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia to its owner's hand.

Temple of Aclazotz

(Transforms from Arguel's Blood Fast.)
{T}: Add {B}.
{T}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Arguel's Blood Fast

{1}{B}, Pay 2 life: Draw a card.
At the beginning of your upkeep, if you have 5 or less life, you may transform Arguel's Blood Fast.

Arguel's Blood Fast // Temple of Aclazotz

Vampire Hexmage

First strike
Sacrifice this creature: Remove all counters from target permanent.

Necrologia

Cast this spell only during your end step.
As an additional cost to cast this spell, pay X life.
Draw X cards.

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Greater Auramancy

Other enchantments you control have shroud. (A permanent with shroud can't be the target of spells or abilities.)
Enchanted creatures you control have shroud.

Swamp

Pain's Reward

Each player may bid life. You start the bidding with a bid of any number. In turn order, each player may top the high bid. The bidding ends if the high bid stands. The high bidder loses life equal to the high bid and draws four cards.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Blitzwing, Adaptive Assailant

Living metal (During your turn, this Vehicle is also a creature.)
At the beginning of combat on your turn, choose flying or indestructible at random. Blitzwing gains that ability until end of turn.
Whenever Blitzwing deals combat damage to a player, convert it.

Blitzwing, Cruel Tormentor

More Than Meets the Eye {3}{B} (You may cast this card converted for {3}{B}.)
At the beginning of your end step, target opponent loses life equal to the life that player lost this turn. If no life is lost this way, convert Blitzwing.

Blitzwing, Cruel Tormentor // Blitzwing, Adaptive Assailant

Sanctum of the Sun

(Transforms from Azor's Gateway.)
{T}: Add X mana of any one color, where X is your life total.

Azor's Gateway

{1}, {T}: Draw a card, then exile a card from your hand. If cards with five or more different mana values are exiled with Azor's Gateway, you gain 5 life, untap Azor's Gateway, and transform it.

Azor's Gateway // Sanctum of the Sun

Doomsday

Search your library and graveyard for five cards and exile the rest. Put the chosen cards on top of your library in any order. You lose half your life, rounded up.

Murderous Betrayal

{B}{B}, Pay half your life, rounded up: Destroy target nonblack creature. It can't be regenerated.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with this creature's toughness.

Solemnity

Players can't get counters.
Counters can't be put on artifacts, creatures, enchantments, or lands.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Wall of Shards

Defender, flying
Cumulative upkeep—An opponent gains 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Celestine, the Living Saint

Flying, lifelink
Healing Tears — At the beginning of your end step, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: This creature gets +1/+1 until end of turn.

Celestial Convergence

This enchantment enters with seven omen counters on it.
At the beginning of your upkeep, remove an omen counter from this enchantment. If there are no omen counters on this enchantment, the player with the highest life total wins the game. If two or more players are tied for highest life total, the game is a draw.

Hex Parasite

{X}{B/P}: Remove up to X counters from target permanent. For each counter removed this way, this creature gets +1/+0 until end of turn. ({B/P} can be paid with either {B} or 2 life.)

Aether Snap

Remove all counters from all permanents and exile all tokens.

Angelic Enforcer

Flying
You have hexproof.
Angelic Enforcer's power and toughness are each equal to your life total.
Whenever this creature attacks, double your life total.

Enduring Angel

Flying, double strike
You have hexproof.
If your life total would be reduced to 0 or less, instead transform this creature and your life total becomes 3. Then if this creature didn't transform this way, you lose the game.

Enduring Angel // Angelic Enforcer

Oketra's Last Mercy

Your life total becomes equal to your starting life total. Lands you control don't untap during your next untap step.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.