Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Urza's Rage

Kicker {8}{R} (You may pay an additional {8}{R} as you cast this spell.)
This spell can't be countered.
Urza's Rage deals 3 damage to any target. If this spell was kicked, instead it deals 10 damage to that permanent or player and the damage can't be prevented.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Strategic Planning

Look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.

Inquisition of Kozilek

Target player reveals their hand. You choose a nonland card from it with mana value 3 or less. That player discards that card.

Stone Rain

Claim the Firstborn

Gain control of target creature with mana value 3 or less until end of turn. Untap that creature. It gains haste until end of turn.

Lightning Helix

Lightning Helix deals 3 damage to any target and you gain 3 life.

Putrefy

Destroy target artifact or creature. It can't be regenerated.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Infuriate

Target creature gets +3/+2 until end of turn.

Gods Willing

Target creature you control gains protection from the color of your choice until end of turn. (It can't be blocked, targeted, dealt damage, enchanted, or equipped by anything of that color.)
Scry 1.

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Snakeskin Veil

Put a +1/+1 counter on target creature you control. It gains hexproof until end of turn. (It can't be the target of spells or abilities your opponents control.)

Village Rites

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

Memory Lapse

Counter target spell. If that spell is countered this way, put it on top of its owner's library instead of into that player's graveyard.

Divine Gambit

Exile target artifact, creature, or enchantment an opponent controls. That player may put a permanent card from their hand onto the battlefield.

Counterspell

Eliminate

Destroy target creature or planeswalker with mana value 3 or less.

Agonizing Remorse

Target opponent reveals their hand. You choose a nonland card from it or a card from their graveyard. Exile that card. You lose 1 life.

Despark

Exile target permanent with mana value 4 or greater.

Natural Order

As an additional cost to cast this spell, sacrifice a green creature.
Search your library for a green creature card, put it onto the battlefield, then shuffle.

Tendrils of Agony

Target player loses 2 life and you gain 2 life.
Storm (When you cast this spell, copy it for each spell cast before it this turn. You may choose new targets for the copies.)

Tainted Pact

Exile the top card of your library. You may put that card into your hand unless it has the same name as another card exiled this way. Repeat this process until you put a card into your hand or you exile two cards with the same name, whichever comes first.

Shock

Weather the Storm

You gain 3 life.
Storm (When you cast this spell, copy it for each spell cast before it this turn.)

Gift of Estates

If an opponent controls more lands than you, search your library for up to three Plains cards, reveal them, put them into your hand, then shuffle.

Harmonize

Scry 1. (Look at the top card of your library. You may put that card on the bottom.)
Draw a card.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Whirlwind Denial

For each spell and ability your opponents control, counter it unless its controller pays {4}.

Sign in Blood

Target player draws two cards and loses 2 life.

Crux of Fate

Choose one —
• Destroy all Dragon creatures.
• Destroy all non-Dragon creatures.

Regrowth

Return target card from your graveyard to your hand.

Mind's Desire

Shuffle your library. Then exile the top card of your library. Until end of turn, you may play that card without paying its mana cost.
Storm (When you cast this spell, copy it for each spell cast before it this turn.)

Time Warp

Target player takes an extra turn after this one.

Blue Sun's Zenith

Target player draws X cards. Shuffle Blue Sun's Zenith into its owner's library.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Lightning Bolt

Lightning Bolt deals 3 damage to any target.

Channel

Until end of turn, any time you could activate a mana ability, you may pay 1 life. If you do, add {C}.

Adventurous Impulse

Look at the top three cards of your library. You may reveal a creature or land card from among them and put it into your hand. Put the rest on the bottom of your library in any order.

Revitalize

Compulsive Research

Target player draws three cards. Then that player discards two cards unless they discard a land card.

Grapeshot

Grapeshot deals 1 damage to any target.
Storm (When you cast this spell, copy it for each spell cast before it this turn. You may choose new targets for the copies.)

Electrolyze

Electrolyze deals 2 damage divided as you choose among one or two targets.
Draw a card.

Ephemerate

Exile target creature you control, then return it to the battlefield under its owner's control.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Faithless Looting

Draw two cards, then discard two cards.
Flashback {2}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Primal Command

Choose two —
• Target player gains 7 life.
• Put target noncreature permanent on top of its owner's library.
• Target player shuffles their graveyard into their library.
• Search your library for a creature card, reveal it, put it into your hand, then shuffle.

Defiant Strike

Target creature gets +1/+0 until end of turn.
Draw a card.

Mizzix's Mastery

Exile target card that's an instant or sorcery from your graveyard. For each card exiled this way, copy it, and you may cast the copy without paying its mana cost. Exile Mizzix's Mastery.
Overload {5}{R}{R}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Dark Ritual

Negate

Thrill of Possibility

As an additional cost to cast this spell, discard a card.
Draw two cards.

Increasing Vengeance

Copy target instant or sorcery spell you control. If this spell was cast from a graveyard, copy that spell twice instead. You may choose new targets for the copies.
Flashback {3}{R}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Doom Blade

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Mana Tithe

Counter target spell unless its controller pays {1}.

Krosan Grip

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Destroy target artifact or enchantment.

Abundant Harvest

Choose land or nonland. Reveal cards from the top of your library until you reveal a card of the chosen kind. Put that card into your hand and the rest on the bottom of your library in a random order.