Sign in Blood

Target player draws two cards and loses 2 life.

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Mikokoro, Center of the Sea

{T}: Add {C}.
{2}, {T}: Each player draws a card.

Elder Brain

Menace
Whenever Elder Brain attacks a player, exile all cards from that player's hand, then they draw that many cards. You may play lands and cast spells from among the exiled cards for as long as they remain exiled. If you cast a spell this way, you may spend mana as though it were mana of any color to cast it.

Murder

Greed

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Victimize

Choose two target creature cards in your graveyard. Sacrifice a creature. If you do, return the chosen cards to the battlefield tapped.

Skullclamp

Equipped creature gets +1/-1.
Whenever equipped creature dies, draw two cards.
Equip {1}

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Pact Weapon

As long as Pact Weapon is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Swamp

Massacre Wurm

When this creature enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Call to the Void

Each player secretly chooses a creature they control and a creature they don't control. Then those choices are revealed. Destroy each creature chosen this way.

Mortuary Mire

Mortuary Mire enters tapped.
When Mortuary Mire enters, you may put target creature card from your graveyard on top of your library.
{T}: Add {B}.

Go for the Throat

Ancient Brass Dragon

Flying
Whenever Ancient Brass Dragon deals combat damage to a player, roll a d20. When you do, put any number of target creature cards with total mana value X or less from graveyards onto the battlefield under your control, where X is the result.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Vedalken Orrery

You may cast spells as though they had flash.

Deadly Dispute

As an additional cost to cast this spell, sacrifice an artifact or creature.
Draw two cards and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Gix's Command

Choose two —
• Put two +1/+1 counters on up to one creature. It gains lifelink until end of turn.
• Destroy each creature with power 2 or less.
• Return up to two creature cards from your graveyard to your hand.
• Each opponent sacrifices a creature with the highest power among creatures they control.

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Soul-Guide Lantern

When this artifact enters, exile target card from a graveyard.
{T}, Sacrifice this artifact: Exile each opponent's graveyard.
{1}, {T}, Sacrifice this artifact: Draw a card.

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Demolition Field

{T}: Add {C}.
{2}, {T}, Sacrifice this land: Destroy target nonbasic land an opponent controls. That land's controller may search their library for a basic land card, put it onto the battlefield, then shuffle. You may search your library for a basic land card, put it onto the battlefield, then shuffle.

Karn's Sylex

Karn's Sylex enters tapped.
Players can't pay life to cast spells or to activate abilities that aren't mana abilities.
{X}, {T}, Exile Karn's Sylex: Destroy each nonland permanent with mana value X or less. Activate only as a sorcery.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Gilded Lotus

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Pristine Talisman

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Dark Ritual

Damnable Pact

Target player draws X cards and loses X life.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Cast Down

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Ob Nixilis, Unshackled

Flying, trample
Whenever an opponent searches their library, that player sacrifices a creature of their choice and loses 10 life.
Whenever another creature dies, put a +1/+1 counter on Ob Nixilis, Unshackled.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Astarion's Thirst

Exile target creature. Put X +1/+1 counters on a commander creature you control, where X is the power of the creature exiled this way.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Portal to Phyrexia

When Portal to Phyrexia enters, each opponent sacrifices three creatures of their choice.
At the beginning of your upkeep, put target creature card from a graveyard onto the battlefield under your control. It's a Phyrexian in addition to its other types.

Sidisi, Undead Vizier

Deathtouch
Exploit (When this creature enters, you may sacrifice a creature.)
When Sidisi, Undead Vizier exploits a creature, you may search your library for a card, put it into your hand, then shuffle.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Dauthi Voidwalker

Shadow (This creature can block or be blocked by only creatures with shadow.)
If a card would be put into an opponent's graveyard from anywhere, instead exile it with a void counter on it.
{T}, Sacrifice Dauthi Voidwalker: Choose an exiled card an opponent owns with a void counter on it. You may play it this turn without paying its mana cost.

Kaya's Ghostform

Enchant creature or planeswalker you control
When enchanted permanent dies or is put into exile, return that card to the battlefield under your control.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Ob Nixilis Reignited

+1: You draw a card and you lose 1 life.
−3: Destroy target creature.
−8: Target opponent gets an emblem with "Whenever a player draws a card, you lose 2 life."

Field of Ruin

{T}: Add {C}.
{2}, {T}, Sacrifice Field of Ruin: Destroy target nonbasic land an opponent controls. Each player searches their library for a basic land card, puts it onto the battlefield, then shuffles.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Imperial Seal

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Sol Ring

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Professor Onyx

Magecraft — Whenever you cast or copy an instant or sorcery spell, each opponent loses 2 life and you gain 2 life.
+1: You lose 1 life. Look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
−3: Each opponent sacrifices a creature with the greatest power among creatures that player controls.
−8: Each opponent may discard a card. If they don't, they lose 3 life. Repeat this process six more times.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.