Heartless Act

Choose one —
• Destroy target creature with no counters on it.
• Remove up to three counters from target creature.

Greater Gargadon

Suspend 10—{R}
Sacrifice an artifact, creature, or land: Remove a time counter from Greater Gargadon. Activate only if Greater Gargadon is suspended.

Glissa Sunslayer

First strike, deathtouch
Whenever Glissa Sunslayer deals combat damage to a player, choose one —
• You draw a card and you lose 1 life.
• Destroy target enchantment.
• Remove up to three counters from target permanent.

Zilortha, Apex of Ikoria

Reach
For each non-Human creature you control, you may have that creature assign its combat damage as though it weren't blocked.

Invasion of Ikoria

(As a Siege enters, choose an opponent to protect it. You and others can attack it. When it's defeated, exile it, then cast it transformed.)
When Invasion of Ikoria enters, search your library and/or graveyard for a non-Human creature card with mana value X or less and put it onto the battlefield. If you search your library this way, shuffle.

Invasion of Ikoria // Zilortha, Apex of Ikoria

Crashing Footfalls

Suspend 4—{G} (Rather than cast this card from your hand, pay {G} and exile it with four time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Create two 4/4 green Rhino creature tokens with trample.

Render Inert

Remove up to five counters from target permanent.
Draw a card.

Vampire Hexmage

First strike
Sacrifice Vampire Hexmage: Remove all counters from target permanent.