Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Mother of Runes

{T}: Target creature you control gains protection from the color of your choice until end of turn.

Monologue Tax

Whenever an opponent casts their second spell each turn, you create a Treasure token.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Imperial Seal

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Ad Nauseam

Reveal the top card of your library and put that card into your hand. You lose life equal to its mana value. You may repeat this process any number of times.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Mondrak, Glory Dominus

If one or more tokens would be created under your control, twice that many of those tokens are created instead.
{1}{W/P}{W/P}, Sacrifice two other artifacts and/or creatures: Put an indestructible counter on Mondrak, Glory Dominus. ({W/P} can be paid with either {W} or 2 life.)

Dockside Chef

{1}{B}, Sacrifice an artifact or creature: Draw a card.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Phyrexian Tower

{T}: Add {C}.
{T}, Sacrifice a creature: Add {B}{B}.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Sign in Blood

Target player draws two cards and loses 2 life.

Chrome Mox

Imprint — When Chrome Mox enters, you may exile a nonartifact, nonland card from your hand.
{T}: Add one mana of any of the exiled card's colors.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Revel in Riches

Whenever a creature an opponent controls dies, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
At the beginning of your upkeep, if you control ten or more Treasures, you win the game.

Reprieve

Return target spell to its owner's hand.
Draw a card.

Disciple of the Vault

Whenever an artifact is put into a graveyard from the battlefield, you may have target opponent lose 1 life.

Nadier's Nightblade

Whenever a token you control leaves the battlefield, each opponent loses 1 life and you gain 1 life.

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Lurrus of the Dream-Den

Companion — Each permanent card in your starting deck has mana value 2 or less. (If this card is your chosen companion, you may put it into your hand from outside the game for {3} as a sorcery.)
Lifelink
Once during each of your turns, you may cast a permanent spell with mana value 2 or less from your graveyard.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Altar of the Brood

Whenever another permanent you control enters, each opponent mills a card.

Lotus Petal

{T}, Sacrifice Lotus Petal: Add one mana of any color.

Urza's Saga

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Urza's Saga gains "{T}: Add {C}."
II — Urza's Saga gains "{2}, {T}: Create a 0/0 colorless Construct artifact creature token with 'This creature gets +1/+1 for each artifact you control.'"
III — Search your library for an artifact card with mana cost {0} or {1}, put it onto the battlefield, then shuffle.

Mana Crypt

At the beginning of your upkeep, flip a coin. If you lose the flip, Mana Crypt deals 3 damage to you.
{T}: Add {C}{C}.

Opposition Agent

Flash
You control your opponents while they're searching their libraries.
While an opponent is searching their library, they exile each card they find. You may play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast them.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Auriok Champion

Protection from black and from red
Whenever another creature enters, you may gain 1 life.

Sol Ring

Mox Diamond

If Mox Diamond would enter, you may discard a land card instead. If you do, put Mox Diamond onto the battlefield. If you don't, put it into its owner's graveyard.
{T}: Add one mana of any color.

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Mirkwood Bats

Flying
Whenever you create or sacrifice a token, each opponent loses 1 life.

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Boromir, Warden of the Tower

Vigilance
Whenever an opponent casts a spell, if no mana was spent to cast it, counter that spell.
Sacrifice Boromir, Warden of the Tower: Creatures you control gain indestructible until end of turn. The Ring tempts you.

Inspiring Statuary

Nonartifact spells you cast have improvise. (Your artifacts can help cast those spells. Each artifact you tap after you're done activating mana abilities pays for {1}.)

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Arcane Signet

Giver of Runes

{T}: Another target creature you control gains protection from colorless or from the color of your choice until end of turn.

Abolish

You may discard a Plains card rather than pay this spell's mana cost.
Destroy target artifact or enchantment.

Mox Amber

{T}: Add one mana of any color among legendary creatures and planeswalkers you control.

Academy Manufactor

If you would create a Clue, Food, or Treasure token, instead create one of each.

Bennie Bracks, Zoologist

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
At the beginning of each end step, if you created a token this turn, draw a card.

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Cathar Commando

Flash (You may cast this spell any time you could cast an instant.)
{1}, Sacrifice this creature: Destroy target artifact or enchantment.

Shattered Sanctum

Shattered Sanctum enters tapped unless you control two or more other lands.
{T}: Add {W} or {B}.

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Agent of the Iron Throne

Commander creatures you own have "Whenever an artifact or creature you control is put into a graveyard from the battlefield, each opponent loses 1 life."

Anointed Procession

If an effect would create one or more tokens under your control, it creates twice that many of those tokens instead.

Swamp

Jeweled Lotus

{T}, Sacrifice Jeweled Lotus: Add three mana of any one color. Spend this mana only to cast your commander.

Ranger-Captain of Eos

When Ranger-Captain of Eos enters, you may search your library for a creature card with mana value 1 or less, reveal it, put it into your hand, then shuffle.
Sacrifice Ranger-Captain of Eos: Your opponents can't cast noncreature spells this turn.

Archivist of Oghma

Flash
Whenever an opponent searches their library, you gain 1 life and draw a card.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Plains

Mox Opal

Metalcraft — {T}: Add one mana of any color. Activate only if you control three or more artifacts.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Grand Abolisher

During your turn, your opponents can't cast spells or activate abilities of artifacts, creatures, or enchantments.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Vampiric Tutor

Drannith Magistrate

Your opponents can't cast spells from anywhere other than their hands.

Cruel Celebrant

Whenever Cruel Celebrant or another creature or planeswalker you control dies, each opponent loses 1 life and you gain 1 life.

Silence

Your opponents can't cast spells this turn.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Vat of Rebirth

Whenever another artifact or creature you control is put into a graveyard from the battlefield, put an oil counter on Vat of Rebirth.
{2}{B}, {T}, Remove four oil counters from Vat of Rebirth: Return target creature card from your graveyard to the battlefield. Activate only as a sorcery.

Fetid Heath

{T}: Add {C}.
{W/B}, {T}: Add {W}{W}, {W}{B}, or {B}{B}.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is Esper Sentinel's power.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Orcish Bowmasters

Flash
When Orcish Bowmasters enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, Orcish Bowmasters deals 1 damage to any target. Then amass Orcs 1.

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Concealed Courtyard

Concealed Courtyard enters tapped unless you control two or fewer other lands.
{T}: Add {W} or {B}.

Soul Warden

Whenever another creature enters, you gain 1 life.

Ophiomancer

At the beginning of each upkeep, if you control no Snakes, create a 1/1 black Snake creature token with deathtouch.

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.