Darksteel Juggernaut

Indestructible
Darksteel Juggernaut's power and toughness are each equal to the number of artifacts you control.
Darksteel Juggernaut attacks each combat if able.

Purphoros, God of the Forge

Indestructible
As long as your devotion to red is less than five, Purphoros isn't a creature.
Whenever another creature you control enters, Purphoros deals 2 damage to each opponent.
{2}{R}: Creatures you control get +1/+0 until end of turn.

Kaldra Compleat

Living weapon
Indestructible
Equipped creature gets +5/+5 and has first strike, trample, indestructible, haste, and "Whenever this creature deals combat damage to a creature, exile that creature."
Equip {7}

Oketra the True

Double strike, indestructible
Oketra the True can't attack or block unless you control at least three other creatures.
{3}{W}: Create a 1/1 white Warrior creature token with vigilance.

Boros Guildgate

This land enters tapped.
{T}: Add {R} or {W}.

Risona, Asari Commander

Haste
Whenever Risona, Asari Commander deals combat damage to a player, if it doesn't have an indestructible counter on it, put an indestructible counter on it.
Whenever combat damage is dealt to you, remove an indestructible counter from Risona.

Heliod, God of the Sun

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature. (Each {W} in the mana costs of permanents you control counts toward your devotion to white.)
Other creatures you control have vigilance.
{2}{W}{W}: Create a 2/1 white Cleric enchantment creature token.

Darksteel Garrison

Fortified land has indestructible.
Whenever fortified land becomes tapped, target creature gets +1/+1 until end of turn.
Fortify {3} ({3}: Attach to target land you control. Fortify only as a sorcery. This card enters unattached and stays on the battlefield if the land leaves.)

Ali from Cairo

Damage that would reduce your life total to less than 1 reduces it to 1 instead.

Boros Garrison

Boros Garrison enters tapped.
When Boros Garrison enters, return a land you control to its owner's hand.
{T}: Add {R}{W}.

Serra the Benevolent

+2: Creatures you control with flying get +1/+1 until end of turn.
−3: Create a 4/4 white Angel creature token with flying and vigilance.
−6: You get an emblem with "If you control a creature, damage that would reduce your life total to less than 1 reduces it to 1 instead."

Darksteel Axe

Indestructible (Effects that say "destroy" don't destroy this artifact.)
Equipped creature gets +2/+0.
Equip {2}

Darksteel Pendant

Indestructible (Effects that say "destroy" don't destroy this artifact.)
{1}, {T}: Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Darksteel Reactor

Indestructible (Effects that say "destroy" don't destroy this artifact.)
At the beginning of your upkeep, you may put a charge counter on Darksteel Reactor.
When Darksteel Reactor has twenty or more charge counters on it, you win the game.

Anya, Merciless Angel

Flying
Anya, Merciless Angel gets +3/+3 for each opponent whose life total is less than half their starting life total.
As long as an opponent's life total is less than half their starting life total, Anya has indestructible.

Hazoret the Fervent

Indestructible, haste
Hazoret the Fervent can't attack or block unless you have one or fewer cards in hand.
{2}{R}, Discard a card: Hazoret deals 2 damage to each opponent.

Hammer of Nazahn

Whenever Hammer of Nazahn or another Equipment you control enters, you may attach that Equipment to target creature you control.
Equipped creature gets +2/+0 and has indestructible.
Equip {4}

Slobad, Goblin Tinkerer

Sacrifice an artifact: Target artifact gains indestructible until end of turn.

Worship

If you control a creature, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Ulamog, the Infinite Gyre

When you cast this spell, destroy target permanent.
Indestructible
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents of their choice.)
When Ulamog, the Infinite Gyre is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

Darksteel Myr

Indestructible (Damage and effects that say "destroy" don't destroy this creature. If its toughness is 0 or less, it's still put into its owner's graveyard.)

Gideon Blackblade

During your turn, Gideon Blackblade is a 4/4 Human Soldier creature with indestructible that's still a planeswalker.
Prevent all damage that would be dealt to Gideon Blackblade during your turn.
+1: Up to one other target creature you control gains your choice of vigilance, lifelink, or indestructible until end of turn.
−6: Exile target nonland permanent.

Darksteel Relic

Indestructible (Effects that say "destroy" don't destroy this artifact.)

Darksteel Gargoyle

Flying
Indestructible (Damage and effects that say "destroy" don't destroy this creature.)

Boros Locket

{T}: Add {R} or {W}.
{R/W}{R/W}{R/W}{R/W}, {T}, Sacrifice Boros Locket: Draw two cards.

Darksteel Sentinel

Flash (You may cast this spell any time you could cast an instant.)
Vigilance
Indestructible (Damage and effects that say "destroy" don't destroy this creature. If its toughness is 0 or less, it's still put into its owner's graveyard.)

Angelic Enforcer

Flying
You have hexproof.
Angelic Enforcer's power and toughness are each equal to your life total.
Whenever Angelic Enforcer attacks, double your life total.

Enduring Angel

Flying, double strike
You have hexproof.
If your life total would be reduced to 0 or less, instead transform Enduring Angel and your life total becomes 3. Then if Enduring Angel didn't transform this way, you lose the game.

Enduring Angel // Angelic Enforcer

Blacksmith's Skill

Target permanent gains hexproof and indestructible until end of turn. If it's an artifact creature, it gets +2/+2 until end of turn.

Zetalpa, Primal Dawn

Flying, double strike, vigilance, trample, indestructible

Purphoros, Bronze-Blooded

Indestructible
As long as your devotion to red is less than five, Purphoros isn't a creature.
Other creatures you control have haste.
{2}{R}: You may put a red creature card or an artifact creature card from your hand onto the battlefield. Sacrifice it at the beginning of the next end step.

Myojin of Cleansing Fire

Myojin of Cleansing Fire enters with a divinity counter on it if you cast it from your hand.
Myojin of Cleansing Fire has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Cleansing Fire: Destroy all other creatures.

Avacyn, the Purifier

Flying
When this creature transforms into Avacyn, the Purifier, it deals 3 damage to each other creature and each opponent.

Archangel Avacyn

Flash
Flying, vigilance
When Archangel Avacyn enters, creatures you control gain indestructible until end of turn.
When a non-Angel creature you control dies, transform Archangel Avacyn at the beginning of the next upkeep.

Archangel Avacyn // Avacyn, the Purifier

Myojin of Roaring Blades

Myojin of Roaring Blades enters with an indestructible counter on it if you cast it from your hand.
Remove an indestructible counter from Myojin of Roaring Blades: It deals 7 damage to each of up to three targets.

Akroma, Vision of Ixidor

Flying, first strike, vigilance, trample
At the beginning of each combat, until end of turn, each other creature you control gets +1/+1 if it has flying, +1/+1 if it has first strike, and so on for double strike, deathtouch, haste, hexproof, indestructible, lifelink, menace, protection, reach, trample, vigilance, and partner.
Partner

Worldslayer

Whenever equipped creature deals combat damage to a player, destroy all permanents other than Worldslayer.
Equip {5} ({5}: Attach to target creature you control. Equip only as a sorcery.)

Rustvale Bridge

Rustvale Bridge enters tapped.
Indestructible
{T}: Add {R} or {W}.

Ulamog, the Ceaseless Hunger

When you cast this spell, exile two target permanents.
Indestructible
Whenever Ulamog, the Ceaseless Hunger attacks, defending player exiles the top twenty cards of their library.

Myojin of Infinite Rage

Myojin of Infinite Rage enters with a divinity counter on it if you cast it from your hand.
Myojin of Infinite Rage has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Infinite Rage: Destroy all lands.

Boros Reckoner

Whenever Boros Reckoner is dealt damage, it deals that much damage to any target.
{R/W}: Boros Reckoner gains first strike until end of turn.

Tajic, Blade of the Legion

Indestructible
Battalion — Whenever Tajic, Blade of the Legion and at least two other creatures attack, Tajic gets +5/+5 until end of turn.

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

Darksteel Forge

Artifacts you control have indestructible. (Effects that say "destroy" don't destroy them. Artifact creatures with indestructible can't be destroyed by damage.)

Foundry Inspector

Artifact spells you cast cost {1} less to cast.

Boros Signet

Elspeth, Knight-Errant

+1: Create a 1/1 white Soldier creature token.
+1: Target creature gets +3/+3 and gains flying until end of turn.
−8: You get an emblem with "Artifacts, creatures, enchantments, and lands you control have indestructible."

Plains

Tyrite Sanctum

{T}: Add {C}.
{2}, {T}: Target legendary creature becomes a God in addition to its other types. Put a +1/+1 counter on it.
{4}, {T}, Sacrifice Tyrite Sanctum: Put an indestructible counter on target God.

Cascading Cataracts

Indestructible
{T}: Add {C}.
{5}, {T}: Add five mana in any combination of colors.

Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Defiler of Faith

Vigilance
As an additional cost to cast white permanent spells, you may pay 2 life. Those spells cost {W} less to cast if you paid life this way. This effect reduces only the amount of white mana you pay.
Whenever you cast a white permanent spell, create a 1/1 white Soldier creature token.

Akiri, Fearless Voyager

Whenever you attack a player with one or more equipped creatures, draw a card.
{W}: You may unattach an Equipment from a creature you control. If you do, tap that creature and it gains indestructible until end of turn.

Darksteel Colossus

Trample (This creature can deal excess combat damage to the player or planeswalker it's attacking.)
Indestructible (Damage and effects that say "destroy" don't destroy this creature.)
If Darksteel Colossus would be put into a graveyard from anywhere, reveal Darksteel Colossus and shuffle it into its owner's library instead.

Konda, Lord of Eiganjo

Vigilance, indestructible
Bushido 5 (Whenever this creature blocks or becomes blocked, it gets +5/+5 until end of turn.)

Loran's Escape

Target artifact or creature gains hexproof and indestructible until end of turn. Scry 1.

Darksteel Ingot

Indestructible (Effects that say "destroy" don't destroy this artifact.)
{T}: Add one mana of any color.

Mountain

Zamriel, Seraph of Steel

Flying
During your turn, equipped creatures you control have indestructible.

Myojin of Blooming Dawn

Myojin of Blooming Dawn enters with an indestructible counter on it if you cast it from your hand.
Remove an indestructible counter from Myojin of Blooming Dawn: Create a 1/1 colorless Spirit creature token for each permanent you control.

Darksteel Citadel

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Darksteel Plate

Indestructible
Equipped creature has indestructible.
Equip {2}

Boros Cluestone

{T}: Add {R} or {W}.
{R}{W}, {T}, Sacrifice Boros Cluestone: Draw a card.

Boros Keyrune

{T}: Add {R} or {W}.
{R}{W}: Boros Keyrune becomes a 1/1 red and white Soldier artifact creature with double strike until end of turn. (It deals both first-strike and regular combat damage.)

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Iroas, God of Victory

Indestructible
As long as your devotion to red and white is less than seven, Iroas isn't a creature.
Creatures you control have menace.
Prevent all damage that would be dealt to attacking creatures you control.

Survive the Night

Target creature gets +1/+0 and gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)
Investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Fortune Thief

Damage that would reduce your life total to less than 1 reduces it to 1 instead.
Morph {R}{R} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Angel of Grace

Flash
Flying
When Angel of Grace enters, until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.
{4}{W}{W}, Exile Angel of Grace from your graveyard: Your life total becomes 10.

Defiler of Instinct

First strike
As an additional cost to cast red permanent spells, you may pay 2 life. Those spells cost {R} less to cast if you paid life this way. This effect reduces only the amount of red mana you pay.
Whenever you cast a red permanent spell, Defiler of Instinct deals 1 damage to any target.