Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Forbidden Friendship

Create a 1/1 red Dinosaur creature token with haste and a 1/1 white Human Soldier creature token.

Lagomos, Hand of Hatred

At the beginning of combat on your turn, create a 2/1 red Elemental creature token with trample and haste. Sacrifice it at the beginning of the next end step.
{T}: Search your library for a card, put it into your hand, then shuffle. Activate only if five or more creatures died this turn.

Tarrian's Soulcleaver

Equipped creature has vigilance.
Whenever another artifact or creature is put into a graveyard from the battlefield, put a +1/+1 counter on equipped creature.
Equip {2}

Elemental Mastery

Enchant creature
Enchanted creature has "{T}: Create X 1/1 red Elemental creature tokens with haste, where X is this creature's power. Exile them at the beginning of the next end step."

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Tevesh Szat, Doom of Fools

+2: Create two 0/1 black Thrull creature tokens.
+1: You may sacrifice another creature or planeswalker. If you do, draw two cards, then draw another card if the sacrificed permanent was a commander.
−10: Gain control of all commanders. Put all commanders from the command zone onto the battlefield under your control.
Tevesh Szat, Doom of Fools can be your commander.
Partner

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Tempt with Vengeance

Tempting offer — Create X 1/1 red Elemental creature tokens with haste. Each opponent may create X 1/1 red Elemental creature tokens with haste. For each opponent who does, create X 1/1 red Elemental creature tokens with haste.

Liliana, Dreadhorde General

Whenever a creature you control dies, draw a card.
+1: Create a 2/2 black Zombie creature token.
−4: Each player sacrifices two creatures of their choice.
−9: Each opponent chooses a permanent they control of each permanent type and sacrifices the rest.

Impulsive Pilferer

When Impulsive Pilferer dies, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
Encore {3}{R} ({3}{R}, Exile this card from your graveyard: For each opponent, create a token copy that attacks that opponent this turn if able. They gain haste. Sacrifice them at the beginning of the next end step. Activate only as a sorcery.)

Sol Ring

Dreadhorde Invasion

At the beginning of your upkeep, you lose 1 life and amass Zombies 1. (Put a +1/+1 counter on an Army you control. It's also a Zombie. If you don't control an Army, create a 0/0 black Zombie Army creature token first.)
Whenever a Zombie token you control with power 6 or greater attacks, it gains lifelink until end of turn.

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent of their choice that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Ghirapur Aether Grid

Tap two untapped artifacts you control: Ghirapur Aether Grid deals 1 damage to any target.

Fling

As an additional cost to cast this spell, sacrifice a creature.
Fling deals damage equal to the sacrificed creature's power to any target.

Priest of Forgotten Gods

{T}, Sacrifice two other creatures: Any number of target players each lose 2 life and sacrifice a creature of their choice. You add {B}{B} and draw a card.

Feign Death

Until end of turn, target creature gains "When this creature dies, return it to the battlefield tapped under its owner's control with a +1/+1 counter on it."

Sadistic Glee

Enchant creature
Whenever a creature dies, put a +1/+1 counter on enchanted creature.

Traveler's Amulet

{1}, Sacrifice Traveler's Amulet: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.

Magus of the Wheel

{1}{R}, {T}, Sacrifice Magus of the Wheel: Each player discards their hand, then draws seven cards.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Orcish Bowmasters

Flash
When Orcish Bowmasters enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, Orcish Bowmasters deals 1 damage to any target. Then amass Orcs 1.

Burning Anger

Enchant creature
Enchanted creature has "{T}: This creature deals damage equal to its power to any target."

Shire Terrace

{T}: Add {C}.
{1}, {T}, Sacrifice Shire Terrace: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Shambling Ghast

When Shambling Ghast dies, choose one —
• Target creature an opponent controls gets -1/-1 until end of turn.
• Create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Animation Module

Whenever one or more +1/+1 counters are put on a permanent you control, you may pay {1}. If you do, create a 1/1 colorless Servo artifact creature token.
{3}, {T}: Choose a counter on target permanent or player. Give that permanent or player another counter of that kind.

Court of Embereth

When Court of Embereth enters, you become the monarch.
At the beginning of your upkeep, create a 3/1 red Knight creature token. Then if you're the monarch, Court of Embereth deals X damage to each opponent, where X is the number of creatures you control.

Evolving Wilds

{T}, Sacrifice Evolving Wilds: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Rain of Gore

If a spell or ability would cause its controller to gain life, that player loses that much life instead.

Deadly Dispute

As an additional cost to cast this spell, sacrifice an artifact or creature.
Draw two cards and create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Juri, Master of the Revue

Whenever you sacrifice a permanent, put a +1/+1 counter on Juri, Master of the Revue.
When Juri dies, it deals damage equal to its power to any target.

Fatal Grudge

As an additional cost to cast this spell, sacrifice a nonland permanent.
Each opponent chooses a permanent they control that shares a card type with the sacrificed permanent and sacrifices it.
Draw a card.

Curse of Opulence

Enchant player
Whenever enchanted player is attacked, create a Gold token. Each opponent attacking that player does the same. (A Gold token is an artifact with "Sacrifice this artifact: Add one mana of any color.")

Loyal Apprentice

Haste
Lieutenant — At the beginning of combat on your turn, if you control your commander, create a 1/1 colorless Thopter artifact creature token with flying. That token gains haste until end of turn.

The Dross Pits

The Dross Pits enters tapped.
{T}: Add {B}.
{1}{B}, {T}, Sacrifice The Dross Pits: Draw a card.

Armillary Sphere

{2}, {T}, Sacrifice Armillary Sphere: Search your library for up to two basic land cards, reveal them, put them into your hand, then shuffle.

Swamp

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Kazuul's Cliffs

Kazuul's Cliffs enters tapped.
{T}: Add {R}.

Kazuul's Fury

As an additional cost to cast this spell, sacrifice a creature.
Kazuul's Fury deals damage equal to the sacrificed creature's power to any target.

Kazuul's Fury // Kazuul's Cliffs

Bitterblossom

At the beginning of your upkeep, you lose 1 life and create a 1/1 black Faerie Rogue creature token with flying.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Descent into Avernus

At the beginning of your upkeep, put two descent counters on Descent into Avernus. Then each player creates X Treasure tokens and Descent into Avernus deals X damage to each player, where X is the number of descent counters on Descent into Avernus.

Morbid Opportunist

Whenever one or more other creatures die, draw a card. This ability triggers only once each turn.

Inventors' Fair

At the beginning of your upkeep, if you control three or more artifacts, you gain 1 life.
{T}: Add {C}.
{4}, {T}, Sacrifice Inventors' Fair: Search your library for an artifact card, reveal it, put it into your hand, then shuffle. Activate only if you control three or more artifacts.

Phyrexian Altar

Sacrifice a creature: Add one mana of any color.

Bloodghast

Bloodghast can't block.
Bloodghast has haste as long as an opponent has 10 or less life.
Landfall — Whenever a land you control enters, you may return Bloodghast from your graveyard to the battlefield.

Diabolic Intent

As an additional cost to cast this spell, sacrifice a creature.
Search your library for a card, put that card into your hand, then shuffle.

Pain Distributor

Menace
Whenever a player casts their first spell each turn, they create a Treasure token.
Whenever an artifact an opponent controls is put into a graveyard from the battlefield, Pain Distributor deals 1 damage to that player.

Emrakul's Hatcher

When Emrakul's Hatcher enters, create three 0/1 colorless Eldrazi Spawn creature tokens. They have "Sacrifice this creature: Add {C}."

Ophiomancer

At the beginning of each upkeep, if you control no Snakes, create a 1/1 black Snake creature token with deathtouch.

Quicksmith Genius

Whenever an artifact you control enters, you may discard a card. If you do, draw a card.

Goblin Bombardment

Sacrifice a creature: Goblin Bombardment deals 1 damage to any target.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Lotus Field

Hexproof
Lotus Field enters tapped.
When Lotus Field enters, sacrifice two lands.
{T}: Add three mana of any one color.

Bucknard's Everfull Purse

{1}, {T}: Roll a d4 and create a number of Treasure tokens equal to the result. The player to your right gains control of Bucknard's Everfull Purse.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Corrupted Conviction

As an additional cost to cast this spell, sacrifice a creature.
Draw two cards.

The Ozolith

Whenever a creature you control leaves the battlefield, if it had counters on it, put those counters on The Ozolith.
At the beginning of combat on your turn, if The Ozolith has counters on it, you may move all counters from The Ozolith onto target creature.

Pitiless Plunderer

Whenever another creature you control dies, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Command Beacon

{T}: Add {C}.
{T}, Sacrifice Command Beacon: Put your commander into your hand from the command zone.

Village Rites

Urabrask's Forge

At the beginning of combat on your turn, put an oil counter on Urabrask's Forge, then create an X/1 red Phyrexian Horror creature token with trample and haste, where X is the number of oil counters on Urabrask's Forge. Sacrifice that token at the beginning of the next end step.

Viscera Seer

Sacrifice a creature: Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Lim-Dûl's Hex

At the beginning of your upkeep, for each player, Lim-Dûl's Hex deals 1 damage to that player unless they pay {B} or {3}.

Ingot Chewer

When Ingot Chewer enters, destroy target artifact.
Evoke {R} (You may cast this spell for its evoke cost. If you do, it's sacrificed when it enters.)

High Market

{T}: Add {C}.
{T}, Sacrifice a creature: You gain 1 life.

Taurean Mauler

Changeling (This card is every creature type.)
Whenever an opponent casts a spell, you may put a +1/+1 counter on Taurean Mauler.

Roiling Vortex

At the beginning of each player's upkeep, Roiling Vortex deals 1 damage to them.
Whenever a player casts a spell, if no mana was spent to cast that spell, Roiling Vortex deals 5 damage to that player.
{R}: Your opponents can't gain life this turn.

Dockside Extortionist

When Dockside Extortionist enters, create X Treasure tokens, where X is the number of artifacts and enchantments your opponents control. (Treasure tokens are artifacts with "{T}, Sacrifice this artifact: Add one mana of any color.")

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Act of Aggression

({R/P} can be paid with either {R} or 2 life.)
Gain control of target creature an opponent controls until end of turn. Untap that creature. It gains haste until end of turn.

Dark Prophecy

Whenever a creature you control dies, you draw a card and you lose 1 life.

Damnation

Destroy all creatures. They can't be regenerated.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Mogg War Marshal

Echo {1}{R} (At the beginning of your upkeep, if this came under your control since the beginning of your last upkeep, sacrifice it unless you pay its echo cost.)
When Mogg War Marshal enters or dies, create a 1/1 red Goblin creature token.

Mountain

Kederekt Parasite

Whenever an opponent draws a card, if you control a red permanent, you may have Kederekt Parasite deal 1 damage to that player.

Soot Imp

Flying
Whenever a player casts a nonblack spell, that player loses 1 life.

Chandra's Ignition

Target creature you control deals damage equal to its power to each other creature and each opponent.

Phyrexian Tower

{T}: Add {C}.
{T}, Sacrifice a creature: Add {B}{B}.

Eaten Alive

As an additional cost to cast this spell, sacrifice a creature or pay {3}{B}.
Exile target creature or planeswalker.

Expedition Map

{2}, {T}, Sacrifice Expedition Map: Search your library for a land card, reveal it, put it into your hand, then shuffle.

Mahadi, Emporium Master

At the beginning of your end step, create a Treasure token for each creature that died this turn. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Command Tower

Goblin Sharpshooter

Goblin Sharpshooter doesn't untap during your untap step.
Whenever a creature dies, untap Goblin Sharpshooter.
{T}: Goblin Sharpshooter deals 1 damage to any target.

Barad-dûr

Barad-dûr enters tapped unless you control a legendary creature.
{T}: Add {B}.
{X}{X}{B}, {T}: Amass Orcs X. Activate only if a creature died this turn.