Extinguish All Hope

Despotic Scepter

{T}: Destroy target permanent you own. It can't be regenerated.

Trinket Mage

When Trinket Mage enters, you may search your library for an artifact card with mana value 1 or less, reveal that card, put it into your hand, then shuffle.

Curse of Bloodletting

Enchant player
If a source would deal damage to enchanted player, it deals double that damage to that player instead.

Curse of the Bloody Tome

Enchant player
At the beginning of enchanted player's upkeep, that player mills two cards.

Blightcaster

Whenever you cast an enchantment spell, you may have target creature get -2/-2 until end of turn.

Curse of Disturbance

Enchant player
Whenever enchanted player is attacked, create a 2/2 black Zombie creature token. Each opponent attacking that player does the same.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Maddening Hex

Enchant player
Whenever enchanted player casts a noncreature spell, roll a d6. Maddening Hex deals damage to that player equal to the result. Then attach Maddening Hex to another one of your opponents chosen at random.

Swamp

Extravagant Replication

At the beginning of your upkeep, create a token that's a copy of another target nonland permanent you control.

Maestros Theater

When Maestros Theater enters, sacrifice it. When you do, search your library for a basic Island, Swamp, or Mountain card, put it onto the battlefield tapped, then shuffle and you gain 1 life.

Paradox Haze

Enchant player
At the beginning of enchanted player's first upkeep each turn, that player gets an additional upkeep step after this step.

Temple of Epiphany

Temple of Epiphany enters tapped.
When Temple of Epiphany enters, scry 1.
{T}: Add {U} or {R}.

Curse of Opulence

Enchant player
Whenever enchanted player is attacked, create a Gold token. Each opponent attacking that player does the same. (A Gold token is an artifact with "Sacrifice this artifact: Add one mana of any color.")

Temple of Deceit

Temple of Deceit enters tapped.
When Temple of Deceit enters, scry 1.
{T}: Add {U} or {B}.

Counterspell

Grixis Panorama

{T}: Add {C}.
{1}, {T}, Sacrifice Grixis Panorama: Search your library for a basic Island, Swamp, or Mountain card, put it onto the battlefield tapped, then shuffle.

Grim Guardian

Constellation — Whenever Grim Guardian or another enchantment you control enters, each opponent loses 1 life.

Curse of Inertia

Enchant player
Whenever a player attacks enchanted player with one or more creatures, that attacking player may tap or untap target permanent of their choice.

Curse of Shallow Graves

Enchant player
Whenever a player attacks enchanted player with one or more creatures, that attacking player may create a tapped 2/2 black Zombie creature token.

Sign in Blood

Target player draws two cards and loses 2 life.

Curse of Surveillance

Enchant player
At the beginning of enchanted player's upkeep, any number of target players other than that player each draw cards equal to the number of Curses attached to that player.

Crystal Chimes

{3}, {T}, Sacrifice Crystal Chimes: Return all enchantment cards from your graveyard to your hand.

Rakdos Carnarium

Rakdos Carnarium enters tapped.
When Rakdos Carnarium enters, return a land you control to its owner's hand.
{T}: Add {B}{R}.

Perilous Research

Draw two cards, then sacrifice a permanent.

Crumbling Necropolis

Crumbling Necropolis enters tapped.
{T}: Add {U}, {B}, or {R}.

Cruel Reality

Enchant player
At the beginning of enchanted player's upkeep, that player sacrifices a creature or planeswalker. If the player can't, they lose 5 life.

Read the Runes

Draw X cards. For each card drawn this way, discard a card unless you sacrifice a permanent.

Silent Arbiter

No more than one creature can attack each combat.
No more than one creature can block each combat.

Sphinx of the Second Sun

Flying
At the beginning of each of your postcombat main phases, there is an additional beginning phase after this phase. (The beginning phase includes the untap, upkeep, and draw steps.)

Doomwake Giant

Constellation — Whenever Doomwake Giant or another enchantment you control enters, creatures your opponents control get -1/-1 until end of turn.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Mountain

Strionic Resonator

{2}, {T}: Copy target triggered ability you control. You may choose new targets for the copy. (A triggered ability uses the words "when," "whenever," or "at.")

Izzet Signet

Rakdos Signet

Curse of the Pierced Heart

Enchant player
At the beginning of enchanted player's upkeep, Curse of the Pierced Heart deals 1 damage to that player or a planeswalker that player controls.

Terminate

Destroy target creature. It can't be regenerated.

Temple of Malice

Temple of Malice enters tapped.
When Temple of Malice enters, scry 1.
{T}: Add {B} or {R}.

Dimir Aqueduct

Dimir Aqueduct enters tapped.
When Dimir Aqueduct enters, return a land you control to its owner's hand.
{T}: Add {U}{B}.

Darkwater Catacombs

Curse of Chaos

Enchant player
Whenever a player attacks enchanted player with one or more creatures, that attacking player may discard a card. If the player does, they draw a card.

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters tapped unless you control two or more basic lands.

Clever Impersonator

You may have Clever Impersonator enter as a copy of any nonland permanent on the battlefield.

Torment of Scarabs

Enchant player
At the beginning of enchanted player's upkeep, that player loses 3 life unless they sacrifice a nonland permanent or discard a card.

God-Eternal Bontu

Menace
When God-Eternal Bontu enters, sacrifice any number of other permanents, then draw that many cards.
When God-Eternal Bontu dies or is put into exile from the battlefield, you may put it into its owner's library third from the top.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Curse of Fool's Wisdom

Enchant player
Whenever enchanted player draws a card, they lose 2 life and you gain 2 life.
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Curse of Unbinding

Enchant player
At the beginning of enchanted player's upkeep, that player reveals cards from the top of their library until they reveal a creature card. Put that card onto the battlefield under your control. That player puts the rest of the revealed cards into their graveyard.

Foreboding Ruins

As Foreboding Ruins enters, you may reveal a Swamp or Mountain card from your hand. If you don't, Foreboding Ruins enters tapped.
{T}: Add {B} or {R}.

Terramorphic Expanse

{T}, Sacrifice Terramorphic Expanse: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Sol Ring

Island

Bitterheart Witch

Deathtouch
When Bitterheart Witch dies, you may search your library for a Curse card, put it onto the battlefield attached to target player, then shuffle.

Thoughtrender Lamia

Constellation — Whenever Thoughtrender Lamia or another enchantment you control enters, each opponent discards a card.

Mirrormade

You may have Mirrormade enter as a copy of any artifact or enchantment on the battlefield.

Curse of Thirst

Enchant player
At the beginning of enchanted player's upkeep, Curse of Thirst deals damage to that player equal to the number of Curses attached to them.

Infectious Curse

Enchant player
Spells you cast that target enchanted player cost {1} less to cast.
At the beginning of enchanted player's upkeep, that player loses 1 life and you gain 1 life.

Accursed Witch

Spells your opponents cast that target Accursed Witch cost {1} less to cast.
When Accursed Witch dies, return it to the battlefield transformed under your control attached to target opponent.

Accursed Witch // Infectious Curse

Choked Estuary

As Choked Estuary enters, you may reveal an Island or Swamp card from your hand. If you don't, Choked Estuary enters tapped.
{T}: Add {U} or {B}.

Command Tower

Lynde, Cheerful Tormentor

Deathtouch
Whenever a Curse is put into your graveyard from the battlefield, return it to the battlefield attached to you at the beginning of the next end step.
At the beginning of your upkeep, you may attach a Curse attached to you to one of your opponents. If you do, draw two cards.

Scheming Symmetry

Choose two target players. Each of them searches their library for a card, then shuffles and puts that card on top.

Claws of Gix

{1}, Sacrifice a permanent: You gain 1 life.

Evolving Wilds

{T}, Sacrifice Evolving Wilds: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Infernal Tribute

{2}, Sacrifice a nontoken permanent: Draw a card.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Leeching Lurker

Lifelink
Nightbound (If a player casts at least two spells during their own turn, it becomes day next turn.)

Curse of Leeches

Enchant player
As this permanent transforms into Curse of Leeches, attach it to a player.
At the beginning of enchanted player's upkeep, they lose 1 life and you gain 1 life.
Daybound (If a player casts no spells during their own turn, it becomes night next turn.)

Curse of Leeches // Leeching Lurker

Dimir Signet

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Reality Shift

Exile target creature. Its controller manifests the top card of their library. (That player puts the top card of their library onto the battlefield face down as a 2/2 creature. If it's a creature card, it can be turned face up any time for its mana cost.)

Nightscape Familiar

Blue spells and red spells you cast cost {1} less to cast.
{1}{B}: Regenerate Nightscape Familiar.

Protean Thaumaturge

Constellation — Whenever an enchantment you control enters, you may have Protean Thaumaturge become a copy of another target creature, except it has this ability.

Thirst for Meaning

Draw three cards. Then discard two cards unless you discard an enchantment card.

Curse of Death's Hold

Enchant player
Creatures enchanted player controls get -1/-1.

Curse of Verbosity

Enchant player
Whenever enchanted player is attacked, you draw a card. Each opponent attacking that player does the same.

Xander's Lounge

({T}: Add {U}, {B}, or {R}.)
Xander's Lounge enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Izzet Boilerworks

Izzet Boilerworks enters tapped.
When Izzet Boilerworks enters, return a land you control to its owner's hand.
{T}: Add {U}{R}.

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Curse of the Restless Dead

Enchant player
Whenever a land enchanted player controls enters, you create a 2/2 black Zombie creature token with decayed. (It can't block. When it attacks, sacrifice it at end of combat.)

Curse of Shaken Faith

Enchant player
Whenever enchanted player casts a spell other than the first spell they cast each turn or copies a spell, Curse of Shaken Faith deals 2 damage to them.

Forgeborn Oreads

Constellation — Whenever Forgeborn Oreads or another enchantment you control enters, Forgeborn Oreads deals 1 damage to any target.

Negate

Curse of Misfortunes

Enchant player
At the beginning of your upkeep, you may search your library for a Curse card that doesn't have the same name as a Curse attached to enchanted player, put it onto the battlefield attached to that player, then shuffle.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.