Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Curse of Bloodletting

Enchant player
If a source would deal damage to enchanted player, it deals double that damage to that player instead.

Zo-Zu the Punisher

Whenever a land enters, Zo-Zu the Punisher deals 2 damage to that land's controller.

Citadel of Pain

At the beginning of each player's end step, Citadel of Pain deals X damage to that player, where X is the number of untapped lands they control.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature of their choice.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Plaguecrafter

When Plaguecrafter enters, each player sacrifices a creature or planeswalker of their choice. Each player who can't discards a card.

Descent into Avernus

At the beginning of your upkeep, put two descent counters on Descent into Avernus. Then each player creates X Treasure tokens and Descent into Avernus deals X damage to each player, where X is the number of descent counters on Descent into Avernus.

Harsh Mentor

Whenever an opponent activates an ability of an artifact, creature, or land on the battlefield, if it isn't a mana ability, Harsh Mentor deals 2 damage to that player.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Fanatic of Mogis

When Fanatic of Mogis enters, it deals damage to each opponent equal to your devotion to red. (Each {R} in the mana costs of permanents you control counts toward your devotion to red.)

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Fiery Emancipation

If a source you control would deal damage to a permanent or player, it deals triple that damage to that permanent or player instead.

Solphim, Mayhem Dominus

If a source you control would deal noncombat damage to an opponent or a permanent an opponent controls, it deals double that damage to that player or permanent instead.
{1}{R/P}{R/P}, Discard two cards: Put an indestructible counter on Solphim, Mayhem Dominus. ({R/P} can be paid with either {R} or 2 life.)

Bedevil

Destroy target artifact, creature, or planeswalker.

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Dictate of the Twin Gods

Flash
If a source would deal damage to a permanent or player, it deals double that damage to that permanent or player instead.

Terminate

Destroy target creature. It can't be regenerated.

Sulfuric Vortex

At the beginning of each player's upkeep, Sulfuric Vortex deals 2 damage to that player.
If a player would gain life, that player gains no life instead.

Gamble

Search your library for a card, put that card into your hand, discard a card at random, then shuffle.

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Arcbond

Choose target creature. Whenever that creature is dealt damage this turn, it deals that much damage to each other creature and each player.

Price of Progress

Price of Progress deals damage to each player equal to twice the number of nonbasic lands that player controls.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Roiling Vortex

At the beginning of each player's upkeep, Roiling Vortex deals 1 damage to them.
Whenever a player casts a spell, if no mana was spent to cast that spell, Roiling Vortex deals 5 damage to that player.
{R}: Your opponents can't gain life this turn.

Infernal Grasp

Destroy target creature. You lose 2 life.

Torbran, Thane of Red Fell

If a red source you control would deal damage to an opponent or a permanent an opponent controls, it deals that much damage plus 2 instead.

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.

Dire Fleet Ravager

Menace, deathtouch
When Dire Fleet Ravager enters, each player loses a third of their life, rounded up.

Rakdos Charm

Choose one —
• Exile target player's graveyard.
• Destroy target artifact.
• Each creature deals 1 damage to its controller.

Spellshock

Whenever a player casts a spell, Spellshock deals 2 damage to that player.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Captive Audience

Captive Audience enters under the control of an opponent of your choice.
At the beginning of your upkeep, choose one that hasn't been chosen —
• Your life total becomes 4.
• Discard your hand.
• Each opponent creates five 2/2 black Zombie creature tokens.

Havoc Festival

Players can't gain life.
At the beginning of each player's upkeep, that player loses half their life, rounded up.

City on Fire

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
If a source you control would deal damage to a permanent or player, it deals triple that damage instead.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Manabarbs

Whenever a player taps a land for mana, Manabarbs deals 1 damage to that player.

Sire of Insanity

At the beginning of each end step, each player discards their hand.

Furnace of Rath

If a source would deal damage to a permanent or player, it deals double that damage to that permanent or player instead.

Fraying Omnipotence

Each player loses half their life, then discards half the cards in their hand, then sacrifices half the creatures they control of their choice. Round up each time.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Rampaging Ferocidon

Menace
Players can't gain life.
Whenever another creature enters, Rampaging Ferocidon deals 1 damage to that creature's controller.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Mount Doom

{T}, Pay 1 life: Add {B} or {R}.
{1}{B}{R}, {T}: Mount Doom deals 1 damage to each opponent.
{5}{B}{R}, {T}, Sacrifice Mount Doom and a legendary artifact: Choose up to two creatures, then destroy the rest. Activate only as a sorcery.

Night's Whisper

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Heartless Hidetsugu

{T}: Heartless Hidetsugu deals damage to each player equal to half that player's life total, rounded down.

Indulgent Tormentor

Flying
At the beginning of your upkeep, draw a card unless target opponent sacrifices a creature of their choice or pays 3 life.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Sign in Blood

Target player draws two cards and loses 2 life.

Dark Ritual

Ankh of Mishra

Whenever a land enters, Ankh of Mishra deals 2 damage to that land's controller.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Diabolic Tutor

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Great Unclean One

Reverberating Summons — At the beginning of your end step, each opponent loses 2 life. Then for each opponent who has less life than you, create a 1/3 black Demon creature token named Plaguebearer of Nurgle.