Go for the Throat

Infectious Curse

Enchant player
Spells you cast that target enchanted player cost {1} less to cast.
At the beginning of enchanted player's upkeep, that player loses 1 life and you gain 1 life.

Accursed Witch

Spells your opponents cast that target Accursed Witch cost {1} less to cast.
When Accursed Witch dies, return it to the battlefield transformed under your control attached to target opponent.

Accursed Witch // Infectious Curse

Chain Reaction

Chain Reaction deals X damage to each creature, where X is the number of creatures on the battlefield.

Curse of Fool's Wisdom

Enchant player
Whenever enchanted player draws a card, they lose 2 life and you gain 2 life.
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Curse of Oblivion

Enchant player
At the beginning of enchanted player's upkeep, that player exiles two cards from their graveyard.

Curse of Thirst

Enchant player
At the beginning of enchanted player's upkeep, Curse of Thirst deals damage to that player equal to the number of Curses attached to them.

Curse of Misfortunes

Enchant player
At the beginning of your upkeep, you may search your library for a Curse card that doesn't have the same name as a Curse attached to enchanted player, put it onto the battlefield attached to that player, then shuffle.

Curse of Shallow Graves

Enchant player
Whenever a player attacks enchanted player with one or more creatures, that attacking player may create a tapped 2/2 black Zombie creature token.

Profane Insight

You draw a card and you lose 1 life. (Then exile this card. You may cast the creature later from exile.)

Foulmire Knight

Foulmire Knight // Profane Insight

Curse of the Pierced Heart

Enchant player
At the beginning of enchanted player's upkeep, Curse of the Pierced Heart deals 1 damage to that player or a planeswalker that player controls.

Kazuul, Tyrant of the Cliffs

Whenever a creature an opponent controls attacks, if you're the defending player, create a 3/3 red Ogre creature token unless that creature's controller pays {3}.

Terminate

Destroy target creature. It can't be regenerated.

Curse of Death's Hold

Enchant player
Creatures enchanted player controls get -1/-1.

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Bedevil

Destroy target artifact, creature, or planeswalker.

Ruin Rat

Deathtouch
When Ruin Rat dies, exile target card from an opponent's graveyard.

Vengeful Pharaoh

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Whenever combat damage is dealt to you or a planeswalker you control, if Vengeful Pharaoh is in your graveyard, destroy target attacking creature, then put Vengeful Pharaoh on top of your library.

Baleful Eidolon

Bestow {4}{B} (If you cast this card for its bestow cost, it's an Aura spell with enchant creature. It becomes a creature again if it's not attached to a creature.)
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Enchanted creature gets +1/+1 and has deathtouch.

Vow of Lightning

Enchant creature
Enchanted creature gets +2/+2, has first strike, and can't attack you or planeswalkers you control.

Ruthless Ripper

Deathtouch
Morph—Reveal a black card in your hand. (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)
When Ruthless Ripper is turned face up, target player loses 2 life.

Torment of Scarabs

Enchant player
At the beginning of enchanted player's upkeep, that player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Humble Defector

{T}: Draw two cards. Target opponent gains control of Humble Defector. Activate only during your turn.

Sleeper Agent

When Sleeper Agent enters, target opponent gains control of it.
At the beginning of your upkeep, Sleeper Agent deals 2 damage to you.

Aether Poisoner

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
When Aether Poisoner enters, you get {E}{E} (two energy counters).
Whenever Aether Poisoner attacks, you may pay {E}{E}. If you do, create a 1/1 colorless Servo artifact creature token.

Fumiko the Lowblood

Fumiko the Lowblood has bushido X, where X is the number of attacking creatures. (Whenever this creature blocks or becomes blocked, it gets +X/+X until end of turn.)
Creatures your opponents control attack each combat if able.

Curse of Bloodletting

Enchant player
If a source would deal damage to enchanted player, it deals double that damage to that player instead.

Pharika's Chosen

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)

Bitter Feud

As Bitter Feud enters, choose two players.
If a source controlled by one of the chosen players would deal damage to the other chosen player or a permanent that player controls, that source deals double that damage to that player or permanent instead.

Mire Triton

Deathtouch
When Mire Triton enters, mill two cards and you gain 2 life. (To mill a card, put the top card of your library into your graveyard.)

Curse of Chaos

Enchant player
Whenever a player attacks enchanted player with one or more creatures, that attacking player may discard a card. If the player does, they draw a card.

Royal Assassin

Vow of Malice

Enchant creature
Enchanted creature gets +2/+2, has intimidate, and can't attack you or planeswalkers you control. (A creature with intimidate can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Curse of Opulence

Enchant player
Whenever enchanted player is attacked, create a Gold token. Each opponent attacking that player does the same. (A Gold token is an artifact with "Sacrifice this artifact: Add one mana of any color.")

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Unlicensed Disintegration

Destroy target creature. If you control an artifact, Unlicensed Disintegration deals 3 damage to that creature's controller.

Bitterheart Witch

Deathtouch
When Bitterheart Witch dies, you may search your library for a Curse card, put it onto the battlefield attached to target player, then shuffle.

Thrill-Kill Assassin

Deathtouch
Unleash (You may have this creature enter with a +1/+1 counter on it. It can't block as long as it has a +1/+1 counter on it.)

Dire Fleet Poisoner

Flash
Deathtouch
When Dire Fleet Poisoner enters, target attacking Pirate you control gets +1/+1 and gains deathtouch until end of turn.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Captive Audience

Captive Audience enters under the control of an opponent of your choice.
At the beginning of your upkeep, choose one that hasn't been chosen —
• Your life total becomes 4.
• Discard your hand.
• Each opponent creates five 2/2 black Zombie creature tokens.

Curse of the Cabal

Target player sacrifices half the permanents they control of their choice, rounded down.
Suspend 2—{2}{B}{B} (Rather than cast this card from your hand, you may pay {2}{B}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
At the beginning of each player's upkeep, if Curse of the Cabal is suspended, that player may sacrifice a permanent of their choice. If the player does, put two time counters on Curse of the Cabal.

Mountain

Xantcha, Sleeper Agent

Xantcha, Sleeper Agent enters under the control of an opponent of your choice.
Xantcha attacks each combat if able and can't attack its owner or planeswalkers its owner controls.
{3}: Xantcha's controller loses 2 life and you draw a card. Any player may activate this ability.

Curse of Vengeance

Enchant player
Whenever enchanted player casts a spell, put a spite counter on Curse of Vengeance.
When enchanted player loses the game, you gain X life and draw X cards, where X is the number of spite counters on Curse of Vengeance.

Orzhov Enforcer

Deathtouch
Afterlife 1 (When this creature dies, create a 1/1 white and black Spirit creature token with flying.)

Murder

Curse of the Nightly Hunt

Enchant player
Creatures enchanted player controls attack each combat if able.

Aether Membrane

Defender; reach (This creature can block creatures with flying.)
Whenever Aether Membrane blocks a creature, return that creature to its owner's hand at end of combat.

Vampire of the Dire Moon

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Gifted Aetherborn

Hand of Silumgar

Banshee of the Dread Choir

Myriad (Whenever this creature attacks, for each opponent other than defending player, you may create a token copy that's tapped and attacking that player or a planeswalker they control. Exile the tokens at end of combat.)
Whenever Banshee of the Dread Choir deals combat damage to a player, that player discards a card.

Cruel Reality

Enchant player
At the beginning of enchanted player's upkeep, that player sacrifices a creature or planeswalker of their choice. If the player can't, they lose 5 life.

Rite of the Raging Storm

Creatures named Lightning Rager can't attack you or planeswalkers you control.
At the beginning of each player's upkeep, that player creates a 5/1 red Elemental creature token named Lightning Rager. It has trample, haste, and "At the beginning of the end step, sacrifice this creature."

Varchild, Betrayer of Kjeldor

Whenever Varchild, Betrayer of Kjeldor deals combat damage to a player, that player creates that many 1/1 red Survivor creature tokens.
Survivors your opponents control can't block, and they can't attack you or planeswalkers you control.
When Varchild leaves the battlefield, gain control of all Survivors.

Boot Nipper

Boot Nipper enters with your choice of a deathtouch counter or a lifelink counter on it.

Mindclaw Shaman

When Mindclaw Shaman enters, target opponent reveals their hand. You may cast an instant or sorcery spell from among those cards without paying its mana cost.

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Blood Reckoning

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Typhoid Rats

Rakdos Charm

Choose one —
• Exile target player's graveyard.
• Destroy target artifact.
• Each creature deals 1 damage to its controller.

Hired Poisoner

Curse of Stalked Prey

Enchant player
Whenever a creature deals combat damage to enchanted player, put a +1/+1 counter on that creature.

Crown of Doom

Whenever a creature attacks you or a planeswalker you control, it gets +2/+0 until end of turn.
{2}: Target player other than Crown of Doom's owner gains control of it. Activate only during your turn.

Swamp

Sudden Spoiling

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Until end of turn, creatures target player controls lose all abilities and have base power and toughness 0/2.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Rancid Rats

Skulk (This creature can't be blocked by creatures with greater power.)
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)