Sign in Blood

Target player draws two cards and loses 2 life.

Needle Specter

Flying
Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever Needle Specter deals combat damage to a player, that player discards that many cards.

Dark Ritual

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Boon of Erebos

Target creature gets +2/+0 until end of turn. Regenerate it. You lose 2 life.

Liliana's Reaver

Deathtouch
Whenever Liliana's Reaver deals combat damage to a player, that player discards a card and you create a tapped 2/2 black Zombie creature token.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

The Rack

As The Rack enters, choose an opponent.
At the beginning of the chosen player's upkeep, The Rack deals X damage to that player, where X is 3 minus the number of cards in their hand.

Ravenous Rats

When Ravenous Rats enters, target opponent discards a card.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Hymn to Tourach

Target player discards two cards at random.

Swamp

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Suffer the Past

Exile X target cards from target player's graveyard. For each card exiled this way, that player loses 1 life and you gain 1 life.

Hypnotic Specter

Flying
Whenever Hypnotic Specter deals damage to an opponent, that player discards a card at random.