Rune of Protection: Black

{W}: The next time a black source of your choice would deal damage to you this turn, prevent that damage.
Cycling {2} ({2}, Discard this card: Draw a card.)

Magister Sphinx

Flying
When Magister Sphinx enters, target player's life total becomes 10.

Auramancer

When Auramancer enters, you may return target enchantment card from your graveyard to your hand.

Stonehorn Dignitary

When Stonehorn Dignitary enters, target opponent skips their next combat phase.

Estrid's Invocation

You may have Estrid's Invocation enter as a copy of an enchantment you control, except it has "At the beginning of your upkeep, you may exile this enchantment. If you do, return it to the battlefield under its owner's control."

Rune of Protection: White

{W}: The next time a white source of your choice would deal damage to you this turn, prevent that damage.
Cycling {2} ({2}, Discard this card: Draw a card.)

Hostage Taker

When Hostage Taker enters, exile another target creature or artifact until Hostage Taker leaves the battlefield. You may cast that card for as long as it remains exiled, and mana of any type can be spent to cast that spell.

Nevermaker

Flying
When Nevermaker leaves the battlefield, put target nonland permanent on top of its owner's library.
Evoke {3}{U} (You may cast this spell for its evoke cost. If you do, it's sacrificed when it enters.)

Rune of Protection: Blue

{W}: The next time a blue source of your choice would deal damage to you this turn, prevent that damage.
Cycling {2} ({2}, Discard this card: Draw a card.)

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Phyrexian Metamorph

({U/P} can be paid with either {U} or 2 life.)
You may have Phyrexian Metamorph enter as a copy of any artifact or creature on the battlefield, except it's an artifact in addition to its other types.

Imprisoned in the Moon

Enchant creature, land, or planeswalker
Enchanted permanent is a colorless land with "{T}: Add {C}" and loses all other card types and abilities.

Nimble Obstructionist

Flash
Flying
Cycling {2}{U} ({2}{U}, Discard this card: Draw a card.)
When you cycle Nimble Obstructionist, counter target activated or triggered ability you don't control.

Reflector Mage

When Reflector Mage enters, return target creature an opponent controls to its owner's hand. That creature's owner can't cast spells with the same name as that creature until your next turn.

Radiant's Judgment

Destroy target creature with power 4 or greater.
Cycling {2} ({2}, Discard this card: Draw a card.)

Astral Slide

Whenever a player cycles a card, you may exile target creature. If you do, return that card to the battlefield under its owner's control at the beginning of the next end step.

Decree of Justice

Create X 4/4 white Angel creature tokens with flying.
Cycling {2}{W} ({2}{W}, Discard this card: Draw a card.)
When you cycle Decree of Justice, you may pay {X}. If you do, create X 1/1 white Soldier creature tokens.

Razaketh's Rite

Search your library for a card, put that card into your hand, then shuffle.
Cycling {B} ({B}, Discard this card: Draw a card.)

Unearth

Return target creature card with mana value 3 or less from your graveyard to the battlefield.
Cycling {2} ({2}, Discard this card: Draw a card.)

Astral Drift

Whenever you cycle Astral Drift or cycle another card while Astral Drift is on the battlefield, you may exile target creature. If you do, return that card to the battlefield under its owner's control at the beginning of the next end step.
Cycling {2}{W} ({2}{W}, Discard this card: Draw a card.)

Horror of the Broken Lands

Whenever you cycle or discard another card, Horror of the Broken Lands gets +2/+1 until end of turn.
Cycling {B} ({B}, Discard this card: Draw a card.)

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Brago, King Eternal

Flying
Whenever Brago, King Eternal deals combat damage to a player, exile any number of target nonland permanents you control, then return those cards to the battlefield under their owner's control.

Eldrazi Displacer

Devoid (This card has no color.)
{2}{C}: Exile another target creature, then return it to the battlefield tapped under its owner's control. ({C} represents colorless mana.)

Sidisi, Undead Vizier

Deathtouch
Exploit (When this creature enters, you may sacrifice a creature.)
When Sidisi, Undead Vizier exploits a creature, you may search your library for a card, put it into your hand, then shuffle.

Thassa, Deep-Dwelling

Indestructible
As long as your devotion to blue is less than five, Thassa isn't a creature.
At the beginning of your end step, exile up to one other target creature you control, then return that card to the battlefield under your control.
{3}{U}: Tap another target creature.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Azorius Signet

Deputy of Detention

When Deputy of Detention enters, exile target nonland permanent an opponent controls and all other nonland permanents that player controls with the same name as that permanent until Deputy of Detention leaves the battlefield.

Sower of Temptation

Flying
When Sower of Temptation enters, gain control of target creature for as long as Sower of Temptation remains on the battlefield.

Duplicant

Imprint — When Duplicant enters, you may exile target nontoken creature.
As long as a card exiled with Duplicant is a creature card, Duplicant has the power, toughness, and creature types of the last creature card exiled with Duplicant. It's still a Shapeshifter.

Spellseeker

When Spellseeker enters, you may search your library for an instant or sorcery card with mana value 2 or less, reveal it, put it into your hand, then shuffle.

Rune of Protection: Red

{W}: The next time a red source of your choice would deal damage to you this turn, prevent that damage.
Cycling {2} ({2}, Discard this card: Draw a card.)

Orzhov Signet

Undead Gladiator

{1}{B}, Discard a card: Return Undead Gladiator from your graveyard to your hand. Activate only during your upkeep.
Cycling {1}{B} ({1}{B}, Discard this card: Draw a card.)

Archaeomancer

When Archaeomancer enters, return target instant or sorcery card from your graveyard to your hand.

Ruthless Sniper

Whenever you cycle or discard a card, you may pay {1}. If you do, put a -1/-1 counter on target creature.

Monk Idealist

When Monk Idealist enters, return target enchantment card from your graveyard to your hand.

Escape Protocol

Whenever you cycle a card, you may pay {1}. When you do, exile target artifact or creature you control, then return it to the battlefield under its owner's control.

Hanna, Ship's Navigator

{1}{W}{U}, {T}: Return target artifact or enchantment card from your graveyard to your hand.

Rune-Scarred Demon

Flying
When this creature enters, search your library for a card, put it into your hand, then shuffle.

Oblivion Ring

When Oblivion Ring enters, exile another target nonland permanent.
When Oblivion Ring leaves the battlefield, return the exiled card to the battlefield under its owner's control.

Neutralize

Counter target spell.
Cycling {2} ({2}, Discard this card: Draw a card.)

Akroma's Blessing

Choose a color. Creatures you control gain protection from the chosen color until end of turn.
Cycling {W} ({W}, Discard this card: Draw a card.)

Ephara, God of the Polis

Indestructible
As long as your devotion to white and blue is less than seven, Ephara isn't a creature.
At the beginning of each upkeep, if you had another creature enter the battlefield under your control last turn, draw a card.

Island Sanctuary

If you would draw a card during your draw step, instead you may skip that draw. If you do, until your next turn, you can't be attacked except by creatures with flying and/or islandwalk.

Cloud of Faeries

Flying
When Cloud of Faeries enters, untap up to two lands.
Cycling {2} ({2}, Discard this card: Draw a card.)

Venser, Shaper Savant

Flash (You may cast this spell any time you could cast an instant.)
When Venser, Shaper Savant enters, return target spell or permanent to its owner's hand.

Puppeteer Clique

Flying
When Puppeteer Clique enters, put target creature card from an opponent's graveyard onto the battlefield under your control. It gains haste. At the beginning of your next end step, exile it.
Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Grasp of Fate

When Grasp of Fate enters, for each opponent, exile up to one target nonland permanent that player controls until Grasp of Fate leaves the battlefield. (Those permanents return under their owners' control.)

Clever Impersonator

You may have Clever Impersonator enter as a copy of any nonland permanent on the battlefield.

Rune of Protection: Green

{W}: The next time a green source of your choice would deal damage to you this turn, prevent that damage.
Cycling {2} ({2}, Discard this card: Draw a card.)

Dimir Signet

Clone

You may have Clone enter as a copy of any creature on the battlefield.

Mulldrifter

Flying
When Mulldrifter enters, draw two cards.
Evoke {2}{U} (You may cast this spell for its evoke cost. If you do, it's sacrificed when it enters.)

Gonti, Lord of Luxury

Deathtouch
When Gonti, Lord of Luxury enters, look at the top four cards of target opponent's library, exile one of them face down, then put the rest on the bottom of that library in a random order. You may cast that card for as long as it remains exiled, and mana of any type can be spent to cast that spell.

Leonin Relic-Warder

When Leonin Relic-Warder enters, you may exile target artifact or enchantment.
When Leonin Relic-Warder leaves the battlefield, return the exiled card to the battlefield under its owner's control.

Noxious Gearhulk

Menace
When Noxious Gearhulk enters, you may destroy another target creature. If a creature is destroyed this way, you gain life equal to its toughness.

Scarab Feast

Exile up to three target cards from a single graveyard.
Cycling {B} ({B}, Discard this card: Draw a card.)

Mesa Enchantress

Whenever you cast an enchantment spell, you may draw a card.

Fiend Hunter

When Fiend Hunter enters, you may exile another target creature.
When Fiend Hunter leaves the battlefield, return the exiled card to the battlefield under its owner's control.

Diluvian Primordial

Flying
When Diluvian Primordial enters, for each opponent, you may cast up to one target instant or sorcery card from that player's graveyard without paying its mana cost. If a spell cast this way would be put into a graveyard, exile it instead.

Soulherder

Whenever a creature is exiled from the battlefield, put a +1/+1 counter on Soulherder.
At the beginning of your end step, you may exile another target creature you control, then return that card to the battlefield under its owner's control.

Crystalline Resonance

Whenever you cycle a card, you may have Crystalline Resonance become a copy of another target permanent until your next turn, except it has this ability.

Zur the Enchanter

Flying
Whenever Zur the Enchanter attacks, you may search your library for an enchantment card with mana value 3 or less, put it onto the battlefield, then shuffle.

Bone Miser

Whenever you discard a creature card, create a 2/2 black Zombie creature token.
Whenever you discard a land card, add {B}{B}.
Whenever you discard a noncreature, nonland card, draw a card.

Archfiend of Ifnir

Flying
Whenever you cycle or discard another card, put a -1/-1 counter on each creature your opponents control.
Cycling {2} ({2}, Discard this card: Draw a card.)

Restoration Specialist

{W}, Sacrifice Restoration Specialist: Return up to one target artifact card and up to one target enchantment card from your graveyard to your hand.

Cloudblazer

Flying
When this creature enters, you gain 2 life and draw two cards.

Sun Titan

Vigilance
Whenever Sun Titan enters or attacks, you may return target permanent card with mana value 3 or less from your graveyard to the battlefield.

Resolute Archangel

Flying
When Resolute Archangel enters, if your life total is less than your starting life total, it becomes equal to your starting life total.

Reconnaissance Mission

Whenever a creature you control deals combat damage to a player, you may draw a card.
Cycling {2} ({2}, Discard this card: Draw a card.)

Sol Ring

Ravenous Chupacabra

When Ravenous Chupacabra enters, destroy target creature an opponent controls.

Vizier of Tumbling Sands

{T}: Untap another target permanent.
Cycling {1}{U} ({1}{U}, Discard this card: Draw a card.)
When you cycle Vizier of Tumbling Sands, untap target permanent.

Agent of Treachery

When Agent of Treachery enters, gain control of target permanent.
At the beginning of your end step, if you control three or more permanents you don't own, draw three cards.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

Angel of Despair

Flying
When Angel of Despair enters, destroy target permanent.

Tribute Mage

When Tribute Mage enters, you may search your library for an artifact card with mana value 2, reveal that card, put it into your hand, then shuffle.

Lavinia of the Tenth

Protection from red
When Lavinia of the Tenth enters, detain each nonland permanent your opponents control with mana value 4 or less. (Until your next turn, those permanents can't attack or block and their activated abilities can't be activated.)

Aven Mindcensor

Flash
Flying
If an opponent would search a library, that player searches the top four cards of that library instead.

Land Tax

At the beginning of your upkeep, if an opponent controls more lands than you, you may search your library for up to three basic land cards, reveal them, put them into your hand, then shuffle.

Cast Out

Flash
When Cast Out enters, exile target nonland permanent an opponent controls until Cast Out leaves the battlefield.
Cycling {W} ({W}, Discard this card: Draw a card.)

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Angelsong

Prevent all combat damage that would be dealt this turn.
Cycling {2} ({2}, Discard this card: Draw a card.)