Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Oblivion Stone

{4}, {T}: Put a fate counter on target permanent.
{5}, {T}, Sacrifice this artifact: Destroy each nonland permanent without a fate counter on it, then remove all fate counters from all permanents.

White Sun's Twilight

You gain X life. Create X 1/1 colorless Phyrexian Mite artifact creature tokens with toxic 1 and "This token can't block." If X is 5 or more, destroy all other creatures. (Players dealt combat damage by a creature with toxic 1 also get a poison counter.)

Sol Ring

Nevinyrral's Disk

This artifact enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

End Hostilities

Destroy all creatures and all permanents attached to creatures.

Serenity

At the beginning of your upkeep, destroy all artifacts and enchantments. They can't be regenerated.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Depopulate

Each player who controls a multicolored creature draws a card. Then destroy all creatures.

Nykthos, Shrine to Nyx

{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Planar Cleansing

Hour of Reckoning

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy all nontoken creatures.

Worldslayer

Whenever equipped creature deals combat damage to a player, destroy all permanents other than this Equipment.
Equip {5} ({5}: Attach to target creature you control. Equip only as a sorcery.)

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

Vanquish the Horde

This spell costs {1} less to cast for each creature on the battlefield.
Destroy all creatures.

Day of Judgment

Caged Sun

As this artifact enters, choose a color.
Creatures you control of the chosen color get +1/+1.
Whenever a land's ability causes you to add one or more mana of the chosen color, add one additional mana of that color.

Shatter the Sky

Each player who controls a creature with power 4 or greater draws a card. Then destroy all creatures.

Sublime Exhalation

Undaunted (This spell costs {1} less to cast for each opponent.)
Destroy all creatures.

Winds of Rath

Destroy all creatures that aren't enchanted. They can't be regenerated.

Sunscour

You may exile two white cards from your hand rather than pay this spell's mana cost.
Destroy all creatures.

Minas Tirith

Minas Tirith enters tapped unless you control a legendary creature.
{T}: Add {W}.
{1}{W}, {T}: Draw a card. Activate only if you attacked with two or more creatures this turn.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, this creature gets +5/+5 and has flying.

Whispersilk Cloak

Equipped creature can't be blocked and has shroud. (It can't be the target of spells or abilities.)
Equip {2}

Rest in Peace

When this enchantment enters, exile all graveyards.
If a card or token would be put into a graveyard from anywhere, exile it instead.

Ravnica at War

Boompile

{T}: Flip a coin. If you win the flip, destroy all nonland permanents.

Steelshaper's Gift

Search your library for an Equipment card, reveal that card, put it into your hand, then shuffle.

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

Magus of the Disk

This creature enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Ondu Skyruins

Ondu Inversion

Ondu Inversion // Ondu Skyruins

Fall of the Thran

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Destroy all lands.
II, III — Each player returns two land cards from their graveyard to the battlefield.

Catastrophe

Destroy all lands or all creatures. Creatures destroyed this way can't be regenerated.

Urza's Sylex

{2}{W}{W}, {T}, Exile Urza's Sylex: Each player chooses six lands they control. Destroy all other permanents. Activate only as a sorcery.
When Urza's Sylex is put into exile from the battlefield, you may pay {2}. If you do, search your library for a planeswalker card, reveal it, put it into your hand, then shuffle.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Mind's Eye

Whenever an opponent draws a card, you may pay {1}. If you do, draw a card.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Homeward Path

{T}: Add {C}.
{T}: Each player gains control of all creatures they own.

Purify

Ravages of War

Mass Calcify

Scourglass

{T}, Sacrifice this artifact: Destroy all permanents except for artifacts and lands. Activate only during your upkeep.

Devastating Mastery

You may pay {2}{W}{W} rather than pay this spell's mana cost.
If the {2}{W}{W} cost was paid, an opponent chooses up to two nonland permanents they control and returns them to their owner's hand.
Destroy all nonland permanents.

Fell the Mighty

Destroy all creatures with power greater than target creature's power.

Sword of the Animist

Equipped creature gets +1/+1.
Whenever equipped creature attacks, you may search your library for a basic land card, put it onto the battlefield tapped, then shuffle.
Equip {2}

Elspeth Tirel

+2: You gain 1 life for each creature you control.
−2: Create three 1/1 white Soldier creature tokens.
−5: Destroy all other permanents except for lands and tokens.

Planar Outburst

Destroy all nonland creatures.
Awaken 4—{5}{W}{W}{W} (If you cast this spell for {5}{W}{W}{W}, also put four +1/+1 counters on target land you control and it becomes a 0/0 Elemental creature with haste. It's still a land.)

Fated Retribution

Destroy all creatures and planeswalkers. If it's your turn, scry 2.

Open the Armory

Search your library for an Aura or Equipment card, reveal it, put it into your hand, then shuffle.

Ancient Tomb

{T}: Add {C}{C}. This land deals 2 damage to you.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Plains

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Commander's Plate

Equipped creature gets +3/+3 and has protection from each color that's not in your commander's color identity.
Equip commander {3}
Equip {5}

Slash the Ranks

Destroy all creatures and planeswalkers except for commanders.

Soulscour

Gilded Lotus

Elspeth, Sun's Champion

+1: Create three 1/1 white Soldier creature tokens.
−3: Destroy all creatures with power 4 or greater.
−7: You get an emblem with "Creatures you control get +2/+2 and have flying."

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Eiganjo, Seat of the Empire

{T}: Add {W}.
Channel — {2}{W}, Discard this card: It deals 4 damage to target attacking or blocking creature. This ability costs {1} less to activate for each legendary creature you control.

Wrath of God

Destroy all creatures. They can't be regenerated.

Martial Coup

Create X 1/1 white Soldier creature tokens. If X is 5 or more, destroy all other creatures.

Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)

Expel the Interlopers

Choose a number between 0 and 10. Destroy all creatures with power greater than or equal to the chosen number.

Citywide Bust

Destroy all creatures with toughness 4 or greater.

Rout

You may cast this spell as though it had flash if you pay {2} more to cast it. (You may cast it any time you could cast an instant.)
Destroy all creatures. They can't be regenerated.

Armageddon

Pearl Medallion

White spells you cast cost {1} less to cast.

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Kirtar's Wrath

Destroy all creatures. They can't be regenerated.
Threshold — If seven or more cards are in your graveyard, instead destroy all creatures, then create two 1/1 white Spirit creature tokens with flying. Creatures destroyed this way can't be regenerated.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.