Organic Extinction

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Destroy all nonartifact creatures.

Mirrodin Besieged

As Mirrodin Besieged enters, choose Mirran or Phyrexian.
• Mirran — Whenever you cast an artifact spell, create a 1/1 colorless Myr artifact creature token.
• Phyrexian — At the beginning of your end step, draw a card, then discard a card. Then if there are fifteen or more artifact cards in your graveyard, target opponent loses the game.

Fabricate

Search your library for an artifact card, reveal it, put it into your hand, then shuffle.

Grand Architect

Other blue creatures you control get +1/+1.
{U}: Target artifact creature becomes blue until end of turn.
Tap an untapped blue creature you control: Add {C}{C}. Spend this mana only to cast artifact spells or activate abilities of artifacts.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Key to the City

{T}, Discard a card: Up to one target creature can't be blocked this turn.
Whenever Key to the City becomes untapped, you may pay {2}. If you do, draw a card.

Rex, Cyber-Hound

Whenever Rex, Cyber-Hound deals combat damage to a player, they mill two cards and you get {E}{E} (two energy counters).
Pay {E}{E}: Choose target creature card in a graveyard. Exile it with a brain counter on it. Activate only as a sorcery.
Rex has all activated abilities of all cards in exile with brain counters on them.

Alloy Myr

Urza, Lord High Artificer

When Urza, Lord High Artificer enters, create a 0/0 colorless Construct artifact creature token with "This creature gets +1/+1 for each artifact you control."
Tap an untapped artifact you control: Add {U}.
{5}: Shuffle your library, then exile the top card. Until end of turn, you may play that card without paying its mana cost.

Ethersworn Sphinx

Affinity for artifacts (This spell costs {1} less to cast for each artifact you control.)
Flying
Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card with lesser mana value. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

Unctus, Grand Metatect

Other blue creatures you control have "Whenever this creature becomes tapped, draw a card, then discard a card."
Other artifact creatures you control get +1/+1.
{U/P}: Until end of turn, target creature you control becomes a blue artifact in addition to its other colors and types. Activate only as a sorcery. ({U/P} can be paid with either {U} or 2 life.)

Thoughtcast

Affinity for artifacts (This spell costs {1} less to cast for each artifact you control.)
Draw two cards.

Patron of the Moon

Moonfolk offering (You may cast this spell any time you could cast an instant by sacrificing a Moonfolk and paying the difference in mana costs between this and the sacrificed Moonfolk. Mana cost includes color.)
Flying
{1}: Put up to two land cards from your hand onto the battlefield tapped.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Silver Myr

Pili-Pala

Flying
{2}, {Q}: Add one mana of any color. ({Q} is the untap symbol.)

Digsite Engineer

Whenever you cast an artifact spell, you may pay {2}. If you do, create a 0/0 colorless Construct artifact creature token with "This creature gets +1/+1 for each artifact you control."

Vedalken Archmage

Whenever you cast an artifact spell, draw a card.

Renowned Weaponsmith

{T}: Add {C}{C}. Spend this mana only to cast artifact spells or activate abilities of artifacts.
{U}, {T}: Search your library for a card named Heart-Piercer Bow or Vial of Dragonfire, reveal it, put it into your hand, then shuffle.

Thought Monitor

Affinity for artifacts (This spell costs {1} less to cast for each artifact you control.)
Flying
When Thought Monitor enters, draw two cards.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Soldevi Machinist

{T}: Add {C}{C}. Spend this mana only to activate abilities of artifacts.

Riddlesmith

Whenever you cast an artifact spell, you may draw a card. If you do, discard a card.

Counterspell

Manifold Key

{1}, {T}: Untap another target artifact.
{3}, {T}: Target creature can't be blocked this turn.

Palladium Myr

Bronze Walrus

When Bronze Walrus enters, scry 2. (Look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)
{T}: Add one mana of any color.

Vedalken Engineer

{T}: Add two mana of any one color. Spend this mana only to cast artifact spells or activate abilities of artifacts.