Defiler of Dreams

Flying
As an additional cost to cast blue permanent spells, you may pay 2 life. Those spells cost {U} less to cast if you paid life this way. This effect reduces only the amount of blue mana you pay.
Whenever you cast a blue permanent spell, draw a card.

Sapphire Medallion

Blue spells you cast cost {1} less to cast.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Fuel for the Cause

Counter target spell, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Ichormoon Gauntlet

Planeswalkers you control have "[0]: Proliferate" and "[−12]: Take an extra turn after this one."
Whenever you cast a noncreature spell, choose a counter on target permanent. Put an additional counter of that kind on that permanent.

Sol Ring

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Viral Drake

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{3}{U}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Mystic Sanctuary

({T}: Add {U}.)
Mystic Sanctuary enters tapped unless you control three or more other Islands.
When Mystic Sanctuary enters untapped, you may put target instant or sorcery card from your graveyard on top of your library.

Corrupted Conscience

Enchant creature
You control enchanted creature.
Enchanted creature has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Magistrate's Scepter

{4}, {T}: Put a charge counter on Magistrate's Scepter.
{T}, Remove three charge counters from Magistrate's Scepter: Take an extra turn after this one.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Throne of Eldraine

As Throne of Eldraine enters, choose a color.
{T}: Add four mana of the chosen color. Spend this mana only to cast monocolored spells of that color.
{3}, {T}: Draw two cards. Spend only mana of the chosen color to activate this ability.

Mercurial Spelldancer

Mercurial Spelldancer can't be blocked.
Whenever you cast a noncreature spell, put an oil counter on Mercurial Spelldancer.
Whenever Mercurial Spelldancer deals combat damage to a player, you may remove two oil counters from it. If you do, when you next cast an instant or sorcery spell this turn, copy that spell. You may choose new targets for the copy.

Serum Sovereign

Flying
Whenever you cast a noncreature spell, put an oil counter on Serum Sovereign.
{U}, Remove an oil counter from Serum Sovereign: Draw a card, then scry 2.

Mage-Ring Network

{T}: Add {C}.
{1}, {T}: Put a storage counter on Mage-Ring Network.
{T}, Remove any number of storage counters from Mage-Ring Network: Add {C} for each storage counter removed this way.

Replicating Ring

{T}: Add one mana of any color.
At the beginning of your upkeep, put a night counter on Replicating Ring. Then if it has eight or more night counters on it, remove all of them and create eight colorless snow artifact tokens named Replicated Ring with "{T}: Add one mana of any color."

Mindsplice Apparatus

Flash
At the beginning of your upkeep, put an oil counter on Mindsplice Apparatus.
Instant and sorcery spells you cast cost {1} less to cast for each oil counter on Mindsplice Apparatus.

Glistening Sphere

Glistening Sphere enters tapped.
When Glistening Sphere enters, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Wicked Slumber

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Tap up to two target creatures. Put a stun counter on either of them. Then put a stun counter on either of them. (If a permanent with a stun counter would become untapped, remove one from it instead.)

Misleading Signpost

Flash
When Misleading Signpost enters during the declare attackers step, you may reselect which player or permanent target attacking creature is attacking. (It can't attack its controller or their permanents.)
{T}: Add {U}.

Archmage Ascension

At the beginning of each end step, if you drew two or more cards this turn, you may put a quest counter on Archmage Ascension.
As long as Archmage Ascension has six or more quest counters on it, if you would draw a card, you may instead search your library for a card, put that card into your hand, then shuffle.

Ominous Seas

Whenever you draw a card, put a foreshadow counter on Ominous Seas.
Remove eight foreshadow counters from Ominous Seas: Create an 8/8 blue Kraken creature token.
Cycling {2} ({2}, Discard this card: Draw a card.)

Mesmerizing Dose

Enchant creature
When Mesmerizing Dose enters, tap enchanted creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Enchanted creature doesn't untap during its controller's untap step.

Darksteel Reactor

Indestructible (Effects that say "destroy" don't destroy this artifact.)
At the beginning of your upkeep, you may put a charge counter on Darksteel Reactor.
When Darksteel Reactor has twenty or more charge counters on it, you win the game.

Academy Ruins

{T}: Add {C}.
{1}{U}, {T}: Put target artifact card from your graveyard on top of your library.

Inkmoth Nexus

{T}: Add {C}.
{1}: Inkmoth Nexus becomes a 1/1 Phyrexian Blinkmoth artifact creature with flying and infect until end of turn. It's still a land. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Everflowing Chalice

Multikicker {2} (You may pay an additional {2} any number of times as you cast this spell.)
Everflowing Chalice enters with a charge counter on it for each time it was kicked.
{T}: Add {C} for each charge counter on Everflowing Chalice.

Empowered Autogenerator

Empowered Autogenerator enters tapped.
{T}: Put a charge counter on Empowered Autogenerator. Add X mana of any one color, where X is the number of charge counters on Empowered Autogenerator.

Steady Progress

Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Draw a card.

Chasm Skulker

Whenever you draw a card, put a +1/+1 counter on Chasm Skulker.
When Chasm Skulker dies, create X 1/1 blue Squid creature tokens with islandwalk, where X is the number of +1/+1 counters on Chasm Skulker. (They can't be blocked as long as defending player controls an Island.)

Astral Cornucopia

Astral Cornucopia enters with X charge counters on it.
{T}: Choose a color. Add one mana of that color for each charge counter on Astral Cornucopia.

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

War Room

{T}: Add {C}.
{3}, {T}, Pay life equal to the number of colors in your commanders' color identity: Draw a card.

Myojin of Cryptic Dreams

Myojin of Cryptic Dreams enters with an indestructible counter on it if you cast it from your hand.
Remove an indestructible counter from Myojin of Cryptic Dreams: Copy target permanent spell you control three times. (The copies become tokens.)

The Millennium Calendar

Whenever you untap one or more permanents during your untap step, put that many time counters on The Millennium Calendar.
{2}, {T}: Double the number of time counters on The Millennium Calendar.
When there are 1,000 or more time counters on The Millennium Calendar, sacrifice it and each opponent loses 1,000 life.

Saprazzan Skerry

Saprazzan Skerry enters tapped with two depletion counters on it.
{T}, Remove a depletion counter from Saprazzan Skerry: Add {U}{U}. If there are no depletion counters on Saprazzan Skerry, sacrifice it.

Serum Snare

Return target nonland permanent to its owner's hand. If that permanent had mana value 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Staff of Compleation

{T}, Pay 1 life: Destroy target permanent you own.
{T}, Pay 2 life: Add one mana of any color.
{T}, Pay 3 life: Proliferate.
{T}, Pay 4 life: Draw a card.
{5}: Untap Staff of Compleation.

Ingenious Prodigy

Skulk (This creature can't be blocked by creatures with greater power.)
Ingenious Prodigy enters with X +1/+1 counters on it.
At the beginning of your upkeep, if Ingenious Prodigy has one or more +1/+1 counters on it, you may remove a +1/+1 counter from it. If you do, draw a card.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Simic Manipulator

Evolve (Whenever a creature you control enters, if that creature has greater power or toughness than this creature, put a +1/+1 counter on this creature.)
{T}, Remove one or more +1/+1 counters from Simic Manipulator: Gain control of target creature with power less than or equal to the number of +1/+1 counters removed this way.

Goldberry, River-Daughter

{T}: Move a counter of each kind not on Goldberry, River-Daughter from another target permanent you control onto Goldberry.
{U}, {T}: Move one or more counters from Goldberry onto another target permanent you control. If you do, draw a card.

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

As Foretold

At the beginning of your upkeep, put a time counter on As Foretold.
Once each turn, you may pay {0} rather than pay the mana cost for a spell you cast with mana value X or less, where X is the number of time counters on As Foretold.

Reject Imperfection

Counter target spell. If that spell's mana value was 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Tekuthal, Inquiry Dominus

Flying
If you would proliferate, proliferate twice instead.
{1}{U/P}{U/P}, Remove three counters from among other artifacts, creatures, and planeswalkers you control: Put an indestructible counter on Tekuthal, Inquiry Dominus. ({U/P} can be paid with either {U} or 2 life.)

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Midnight Clock

{T}: Add {U}.
{2}{U}: Put an hour counter on Midnight Clock.
At the beginning of each upkeep, put an hour counter on Midnight Clock.
When the twelfth hour counter is put on Midnight Clock, shuffle your hand and graveyard into your library, then draw seven cards. Exile Midnight Clock.

Flux Channeler

Whenever you cast a noncreature spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Gitaxian Anatomist

When Gitaxian Anatomist enters, you may tap it. If you do, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Guildpact Informant

Flying
Whenever Guildpact Informant deals combat damage to a player or planeswalker, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Reliquary Tower

Contentious Plan

Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Transmogrifying Wand

Transmogrifying Wand enters with three charge counters on it.
{1}, {T}, Remove a charge counter from Transmogrifying Wand: Destroy target creature. Its controller creates a 2/4 white Ox creature token. Activate only as a sorcery.

Ripples of Potential

Proliferate, then choose any number of permanents you control that had a counter put on them this way. Those permanents phase out. (To proliferate, choose any number of permanents and/or players, then give each another counter of each kind already there. Treat phased-out permanents and anything attached to them as though they don't exist until their controller's next turn.)

Snow-Covered Island

Vivisurgeon's Insight

Draw three cards. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Lux Cannon

{T}: Put a charge counter on Lux Cannon.
{T}, Remove three charge counters from Lux Cannon: Destroy target permanent.

Nesting Grounds

{T}: Add {C}.
{1}, {T}: Move a counter from target permanent you control onto another target permanent. Activate only as a sorcery.

Nykthos, Shrine to Nyx

{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Blast Zone

Blast Zone enters with a charge counter on it.
{T}: Add {C}.
{X}{X}, {T}: Put X charge counters on Blast Zone.
{3}, {T}, Sacrifice Blast Zone: Destroy each nonland permanent with mana value equal to the number of charge counters on Blast Zone.

Sword of Truth and Justice

Equipped creature gets +2/+2 and has protection from white and from blue.
Whenever equipped creature deals combat damage to a player, put a +1/+1 counter on a creature you control, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Equip {2}

Radstorm

Storm (When you cast this spell, copy it for each spell cast before it this turn.)
Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)