Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Cut of the Profits

Casualty 3 (As you cast this spell, you may sacrifice a creature with power 3 or greater. When you do, copy this spell.)
You draw X cards and you lose X life.

Agent of Masks

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Ancient Craving

You draw three cards and you lose 3 life.

Abiding Grace

At the beginning of your end step, choose one —
• You gain 1 life.
• Return target creature card with mana value 1 from your graveyard to the battlefield.

Celebrate the Harvest

Search your library for up to X basic land cards, where X is the number of different powers among creatures you control. Put those cards onto the battlefield tapped, then shuffle.

Baldur's Gate

{T}: Add {C}.
{2}, {T}: Add X mana of any one color, where X is the number of other Gates you control.

Court of Bounty

When this enchantment enters, you become the monarch.
At the beginning of your upkeep, you may put a land card from your hand onto the battlefield. If you're the monarch, instead you may put a creature or land card from your hand onto the battlefield.

Filthy Cur

Whenever this creature is dealt damage, you lose that much life.

Bilbo, Birthday Celebrant

If you would gain life, you gain that much life plus 1 instead.
{2}{W}{B}{G}, {T}, Exile Bilbo: Search your library for any number of creature cards, put them onto the battlefield, then shuffle. Activate only if you have 111 or more life.

Plea for Guidance

Search your library for up to two enchantment cards, reveal them, put them into your hand, then shuffle.

Bellowing Saddlebrute

Raid — When this creature enters, you lose 4 life unless you attacked this turn.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Manor Gate

This land enters tapped.
As this land enters, choose a color other than green.
{T}: Add {G} or one mana of the chosen color.

Ajani's Mantra

At the beginning of your upkeep, you may gain 1 life.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Cruel Bargain

Draw four cards. You lose half your life, rounded up.

Swamp

Exquisite Archangel

Flying
If you would lose the game, instead exile this creature and your life total becomes equal to your starting life total.

Circuitous Route

Search your library for up to two basic land cards and/or Gate cards, put them onto the battlefield tapped, then shuffle.

Corpse Augur

When this creature dies, you draw X cards and you lose X life, where X is the number of creature cards in target player's graveyard.

Baleful Force

At the beginning of each upkeep, you draw a card and you lose 1 life.

Unholy Fiend

At the beginning of your end step, you lose 1 life.

Cloistered Youth

At the beginning of your upkeep, you may transform this creature.

Cloistered Youth // Unholy Fiend

Castle Locthwain

This land enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Angel of Grace

Flash
Flying
When this creature enters, until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.
{4}{W}{W}, Exile this card from your graveyard: Your life total becomes 10.

Black Dragon Gate

This land enters tapped.
As this land enters, choose a color other than black.
{T}: Add {B} or one mana of the chosen color.

Frontier Guide

{3}{G}, {T}: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Planar Bridge

{8}, {T}: Search your library for a permanent card, put it onto the battlefield, then shuffle.

Bad Deal

You draw two cards and each opponent discards two cards. Each player loses 2 life.

Night Dealings

Whenever a source you control deals damage to another player, put that many theft counters on this enchantment.
{2}{B}{B}, Remove X theft counters from this enchantment: Search your library for a nonland card with mana value X, reveal it, put it into your hand, then shuffle.

Citadel Gate

This land enters tapped.
As this land enters, choose a color other than white.
{T}: Add {W} or one mana of the chosen color.

Asmodeus the Archfiend

Binding Contract — If you would draw a card, exile the top card of your library face down instead.
{B}{B}{B}: Draw seven cards.
{B}: Return all cards exiled with Asmodeus to their owner's hand and you lose that much life.

Glass-Cast Heart

Whenever one or more Vampires you control attack, create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this token: Draw a card.")
{B}, {T}, Pay 1 life: Create a 1/1 white and black Vampire creature token with lifelink.
{B}{B}, {T}, Sacrifice this artifact and thirteen Blood tokens: Each opponent loses 13 life and you gain 13 life.

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra's power.

Golgari Guildgate

This land enters tapped.
{T}: Add {B} or {G}.

Henrika, Infernal Seer

Flying, deathtouch, lifelink
{1}{B}{B}: Each creature you control with flying, deathtouch, and/or lifelink gets +1/+0 until end of turn.

Henrika Domnathi

Flying
At the beginning of combat on your turn, choose one that hasn't been chosen —
• Each player sacrifices a creature of their choice.
• You draw a card and you lose 1 life.
• Transform Henrika.

Henrika Domnathi // Henrika, Infernal Seer

Long Rest

Return X target cards with different mana values from your graveyard to your hand. If eight or more cards were returned to your hand this way, your life total becomes equal to your starting life total. Exile Long Rest.

Blightspeaker

{T}: Target player loses 1 life.
{4}, {T}: Search your library for a Rebel permanent card with mana value 3 or less, put it onto the battlefield, then shuffle.

Orzhov Guildgate

This land enters tapped.
{T}: Add {W} or {B}.

Myrkul, Lord of Bones

As long as your life total is less than or equal to half your starting life total, Myrkul has indestructible.
Whenever another nontoken creature you control dies, you may exile it. If you do, create a token that's a copy of that card, except it's an enchantment and loses all other card types.

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Accomplished Alchemist

{T}: Add one mana of any color.
{T}: Add X mana of any one color, where X is the amount of life you gained this turn.

Selesnya Guildmage

{3}{G}: Create a 1/1 green Saproling creature token.
{3}{W}: Creatures you control get +1/+1 until end of turn.

Moon-Blessed Cleric

Divine Intervention — When this creature enters, you may search your library for an enchantment card, reveal it, then shuffle and put that card on top.

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Tree of Redemption

Defender
{T}: Exchange your life total with this creature's toughness.

Harvest Season

Search your library for up to X basic land cards, where X is the number of tapped creatures you control, put those cards onto the battlefield tapped, then shuffle.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with this creature's toughness.

Hoarding Broodlord

Convoke
Flying
When this creature enters, search your library for a card, exile it face down, then shuffle. For as long as that card remains exiled, you may play it.
Spells you cast from exile have convoke.

Plains

Doomsday

Search your library and graveyard for five cards and exile the rest. Put the chosen cards on top of your library in any order. You lose half your life, rounded up.

Angelic Enforcer

Flying
You have hexproof.
Angelic Enforcer's power and toughness are each equal to your life total.
Whenever this creature attacks, double your life total.

Enduring Angel

Flying, double strike
You have hexproof.
If your life total would be reduced to 0 or less, instead transform this creature and your life total becomes 3. Then if this creature didn't transform this way, you lose the game.

Enduring Angel // Angelic Enforcer

Genesis Hydra

When you cast this spell, reveal the top X cards of your library. You may put a nonland permanent card with mana value X or less from among them onto the battlefield. Then shuffle the rest into your library.
This creature enters with X +1/+1 counters on it.

Clawing Torment

Enchant artifact or creature
As long as enchanted permanent is a creature, it gets -1/-1 and can't block.
Enchanted permanent has "At the beginning of your upkeep, you lose 1 life."

Demonic Lore

When this enchantment enters, draw three cards.
At the beginning of your end step, you lose 2 life for each card in your hand.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Death Wish

You may put a card you own from outside the game into your hand. You lose half your life, rounded up. Exile Death Wish.

Archon of Coronation

Flying
When this creature enters, you become the monarch.
As long as you're the monarch, damage doesn't cause you to lose life. (When a creature deals combat damage to you, its controller still becomes the monarch.)

Magus of the Mirror

{T}, Sacrifice this creature: Exchange life totals with target opponent. Activate only during your upkeep.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Chalice of Death

Chalice of Life

{T}: You gain 1 life. Then if you have at least 10 life more than your starting life total, transform this artifact.

Chalice of Life // Chalice of Death

Audacious Thief

Whenever this creature attacks, you draw a card and you lose 1 life.

Green Sun's Twilight

Reveal the top X plus one cards of your library. Choose a creature card and/or a land card from among them. Put those cards into your hand and the rest on the bottom of your library in a random order. If X is 5 or more, instead put the chosen cards onto the battlefield or into your hand and the rest on the bottom of your library in a random order.

Blessing of Leeches

Flash
Enchant creature
At the beginning of your upkeep, you lose 1 life.
{0}: Regenerate enchanted creature.

Torgaar, Famine Incarnate

As an additional cost to cast this spell, you may sacrifice any number of creatures. This spell costs {2} less to cast for each creature sacrificed this way.
When Torgaar enters, up to one target player's life total becomes half their starting life total, rounded down.

Aurora of Emrakul

Flying, deathtouch
Whenever this creature attacks, each opponent loses 3 life.

Cryptolith Fragment

This artifact enters tapped.
{T}: Add one mana of any color. Each player loses 1 life.
At the beginning of your upkeep, if each player has 10 or less life, transform this artifact.

Cryptolith Fragment // Aurora of Emrakul

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Mastermind's Acquisition

Choose one —
• Search your library for a card, put it into your hand, then shuffle.
• Put a card you own from outside the game into your hand.

Ambition's Cost

Far Wanderings

Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
Threshold — If seven or more cards are in your graveyard, instead search your library for up to three basic land cards, put them onto the battlefield tapped, then shuffle.

Forest

Search for Blex

Look at the top five cards of your library. You may put any number of them into your hand and the rest into your graveyard. You lose 3 life for each card you put into your hand this way.

Blex, Vexing Pest

Other Pests, Bats, Insects, Snakes, and Spiders you control get +1/+1.
When Blex dies, you gain 4 life.

Blex, Vexing Pest // Search for Blex

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Abzan Charm

Choose one —
• Exile target creature with power 3 or greater.
• You draw two cards and you lose 2 life.
• Distribute two +1/+1 counters among one or two target creatures.

Illicit Shipment

Casualty 3 (As you cast this spell, you may sacrifice a creature with power 3 or greater. When you do, copy this spell.)
Search your library for a card, put it into your hand, then shuffle.

Ajani, Strength of the Pride

+1: You gain life equal to the number of creatures you control plus the number of planeswalkers you control.
−2: Create a 2/2 white Cat Soldier creature token named Ajani's Pridemate with "Whenever you gain life, put a +1/+1 counter on this token."
0: If you have at least 15 life more than your starting life total, exile Ajani and each artifact and creature your opponents control.

Gond Gate

Gates you control enter untapped.
{T}: Add {C}.
{T}: Add one mana of any color that a Gate you control could produce.

Grinning Demon

At the beginning of your upkeep, you lose 2 life.
Morph {2}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)