Laboratory Maniac

If you would draw a card while your library has no cards in it, you win the game instead.

Vessel of Volatility

{1}{R}, Sacrifice Vessel of Volatility: Add {R}{R}{R}{R}.

Negate

Pact of the Titan

Create a 4/4 red Giant creature token.
At the beginning of your next upkeep, pay {4}{R}. If you don't, you lose the game.

Underworld Breach

Each nonland card in your graveyard has escape. The escape cost is equal to the card's mana cost plus exile three other cards from your graveyard. (You may cast cards from your graveyard for their escape cost.)
At the beginning of the end step, sacrifice Underworld Breach.

Burning Inquiry

Each player draws three cards, then discards three cards at random.

Young Pyromancer

Whenever you cast an instant or sorcery spell, create a 1/1 red Elemental creature token.

Lightning Bolt

Lightning Bolt deals 3 damage to any target.

Thassa's Oracle

When Thassa's Oracle enters, look at the top X cards of your library, where X is your devotion to blue. Put up to one of them on top of your library and the rest on the bottom of your library in a random order. If X is greater than or equal to the number of cards in your library, you win the game. (Each {U} in the mana costs of permanents you control counts toward your devotion to blue.)

Altar of Dementia

Sacrifice a creature: Target player mills cards equal to the sacrificed creature's power.

Runaway Steam-Kin

Whenever you cast a red spell, if Runaway Steam-Kin has fewer than three +1/+1 counters on it, put a +1/+1 counter on Runaway Steam-Kin.
Remove three +1/+1 counters from Runaway Steam-Kin: Add {R}{R}{R}.